Appl Clin Inform 2025; 16(05): 1917-1924
DOI: 10.1055/a-2771-6216
Brief Scientific Communication

AI-TransLATE: Validation of a Speech-Based Multilingual Interpretation Tool in Critical Care

Authors

  • Ibrahim S. Karakus

    1   Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, United States
  • Shashank Gupta

    2   Department of Anesthesiology and Perioperative Medicine, Rochester, Minnesota, United States
  • Rana Gur

    1   Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, United States
  • Marco A. Bracamonte Aranibar

    3   Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota, United States
  • Abdelhamed Elgazar

    2   Department of Anesthesiology and Perioperative Medicine, Rochester, Minnesota, United States
  • Hossam Gad

    2   Department of Anesthesiology and Perioperative Medicine, Rochester, Minnesota, United States
  • Xuechao Hao

    2   Department of Anesthesiology and Perioperative Medicine, Rochester, Minnesota, United States
  • Fabio Morales Salas

    3   Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota, United States
  • Sude Kilickaya

    4   Department of Biomedical Engineering, University of Minnesota, Twin Cities, Minnesota, United States
  • Alexander Niven

    1   Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, United States
  • Oguz Kilickaya

    2   Department of Anesthesiology and Perioperative Medicine, Rochester, Minnesota, United States
  • Amelia Barwise

    1   Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, United States
    5   Division of Biomedical Ethics, Rochester, Department of Quantitative Health Science, Minnesota, United States

Funding This study was supported by the Critical Care Research Committee Mayo Clinic (grant no.: CCR96BARWI); the National Center for Advancing Translational Sciences (NCATS; grant no.: UL1 TR002377).

Abstract

Background

Effective communication in the intensive care unit (ICU) is essential, particularly for patients with non-English language preference, yet timely access to professional interpreters remains limited. While artificial intelligence (AI)-based translation tools have been explored in outpatient and nonacute care settings, studies evaluating their use in acute care, environments such as the ICU remain limited. To address this gap, we developed AI-TransLATE (AI-enhanced Transition to Language-Agnostic Transcultural Engagement), a speech-based translation tool designed for multilingual communication in critical care settings.

Objectives

This study aimed to assess the interpretation quality of AI-TransLATE across four languages—Spanish, Chinese, Arabic, and Turkish—using scripted ICU scenarios.

Methods

We created ICU communication scripts and recorded bilingual research team members simulating clinical interactions. Two independent bilingual evaluators assessed interpretation quality using a 5-point Likert scale across fluency, adequacy, meaning preservation, and severity of errors. Clarity and cultural appropriateness were also rated. Percentage agreement was used to assess interrater agreement.

Results

AI-TransLATE achieved acceptable composite scores (≥16/20) across all languages. Spanish and Turkish performed consistently well; Chinese and Arabic showed variability due to omissions and terminology errors.

Conclusion

AI-TransLATE shows promise as a clinical communication tool, but further evaluation in real-world, unscripted ICU settings is needed.

Protection of Human and Animal Subjects

The study was performed in compliance with the World Medical Association Declaration of Helsinki on Ethical Principles for Medical Research Involving Human Subjects, and was reviewed by Mayo Clinic Institutional Review Board (identifier: 25-001569).


Note

AI-TransLATE, the tool evaluated in this study, was developed by members of the study team. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the National Institutes of Health. Artificial intelligence tools were used for language refinement and scenario generation; all conceptualization, study design, and data analysis were conducted independently by the authors.




Publication History

Received: 10 July 2024

Accepted: 12 December 2025

Accepted Manuscript online:
16 December 2025

Article published online:
24 December 2025

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