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Endoscopy 1995; 27(8): 593-596
DOI: 10.1055/s-2007-1005764
Original Article

© Georg Thieme Verlag KG Stuttgart · New York

Endoscopic Features of Helicobacter pylori-Related Gastritis

A. Bah1 , E. Saraga2 , D. Armstrong1 , D. Vouillamoz1 , G. Dorta1 , P. Duroux1 , B. Weber1 , F. Froehlich1 , A. L. Blum1 , J. F. Schnegg1
  • 1Department of Internal Medicine, Division of Gastroenterology, CHUV/PMU, Lausanne, Switzerland
  • 2Institute of Pathology, CHUV/PMU, Lausanne, Switzerland
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Publication History

Publication Date:
17 March 2008 (online)

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Abstract

Background and Study Aims: It is still controversial whether certain endoscopic features can be used to diagnose Helicobacter pylori (Hp)-related gastritis. To clarify this issue, we performed two consecutive prospective studies.

Patients and Methods: In the first study, we tried to identify endoscopic criteria associated with Hp-related gastritis from a total of 66 predefined gastric features on endoscopy. These features were selected by a stepwise logistic regression analysis in 101 patients. The validity of these features gained from this first study was then evaluated in a second study in 86 patients (40 with Hp gastritis, 8 with Hp-unrelated gastritis and 38 with normal gastric mucosa).

Results: Three features, namely an abnormal antral surface texture, a mammillated corpus surface, and white antral erosions, were identified in the first study as independent predictors of Hp-related gastritis. However, the sensitivity and specificity of these three criteria, as assessed in the second study, were only 75 % and 63 % respectively.

Conclusions: We conclude that it is not possible to diagnose Hp-related gastritis on the basis of the endoscopic appearance alone. The diagnosis should be based on other criteria, such as a rapid urease test, or a histological examination of gastric biopsies, or both.

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