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Am J Perinatol 1997; 14(5): 263-265
DOI: 10.1055/s-2007-994140
ORIGINAL ARTICLE

© 1997 by Thieme Medical Publishers, Inc.

The Rate of Severe Preeclampsia is Increased in Triplet as Compared to Twin Gestations

Joan M. Mastrobattista1 , Daniel W. Skupski2 , Manju Monga1 , Jorge D. Blanco1 , Phyllis August2
  • 1Departments of Obstetrics, Gynecology, and Reproductive Sciences, The University of Texas Medical School at Houston, Houston, Texas
  • 2The New York Hospital Cornell Medical Center, New York, New York
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Publication History

Publication Date:
04 March 2008 (online)

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ABSTRACT

The objective of this study was to determine if the rate of preeclampsia is increased in triplet as compared to twin gestations. Fifty-three triplet pregnancies between 1986 and 1993 at The New York Hospital-Cornell Medical Center were reviewed. These were matched for maternal age, parity, and race to twin gestations (N = 53) from the same population. Severe preeclampsia was defined by standard criteria. Student's t-test, Fisher exact test, and Chi-square were used for statistical analysis. The rate of severe preeclampsia was increased significantly in the triplet group 12 of 53 (22.6%) as compared with the twin group 3 of 53 (5.7%) (OR = 4.9, 95% Cl 1.2-23.5, p = 0.02). The rate of overall preeclampsia was not significantly different in the triplet 18 of 53 (33.96%) or twin 12 of 53 (22.6%) groups. In this retrospective, case-controlled study, the rate of severe preeclampsia was significantly increased in triplet gestations as compared to twins although the overall rate of preeclampsia was not. This information may be useful in counseling patients with high order multifetal gestations.

Keywords

Triplets, multiple gestations - preeclampsia

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