Concept Paper on the Technique of Cryopreservation, Removal and Transplantation of Ovarian Tissue for Fertility Preservation

Matthias W. Beckmann; Laura Lotz; Bettina Toth; Dunja Maria Baston-Büst; Tanja Fehm; Torsten Frambach; Ariane Germeyer; Maren Goeckenjan; Felix Häberlin; Melanie Henes; Jens Hirchenhain; Stephanie Hübner; Matthias Korell; Jan-Steffen Krüssel; Andreas Müller; Jochen Reinsberg; Roxana Schwab; Stephan Seitz; Marc Sütterlin; Hans van der Ven; Katrin van der Ven; Katharina Winkler-Crepaz; Pauline Wimberger; Michael von Wolff; Jana Liebenthron; Ralf Dittrich

doi:10.1055/a-0664-8619

Geburtshilfe und Frauenheilkunde, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Geburtshilfe Frauenheilkd 2019; 79(01): 53-62
DOI: 10.1055/a-0664-8619

GebFra Science

Review/Übersicht

Georg Thieme Verlag KG Stuttgart · New York

Concept Paper on the Technique of Cryopreservation, Removal and Transplantation of Ovarian Tissue for Fertility Preservation

Artikel in mehreren Sprachen: English | deutsch

Matthias W. Beckmann

¹Frauenklinik, Universitätsklinikum Erlangen, Erlangen, Germany

,

Laura Lotz

¹Frauenklinik, Universitätsklinikum Erlangen, Erlangen, Germany

,

Bettina Toth

²Gynäkologische Endokrinologie und Reproduktionsmedizin, Universitätsklinikum Innsbruck, Innsbruck, Austria

,

Dunja Maria Baston-Büst

³Frauenklinik, Universitätsklinikum Düsseldorf, Düsseldorf, Germany

,

Tanja Fehm

³Frauenklinik, Universitätsklinikum Düsseldorf, Düsseldorf, Germany

,

Torsten Frambach

⁴Frauenklinik, Krankenhaus St. Joseph Stift Bremen, Bremen, Germany

,

Ariane Germeyer

⁵Frauenklinik, Universitätsklinikum Heidelberg, Heidelberg, Germany

,

Maren Goeckenjan

⁶Frauenklinik, Universitätsklinikum Dresden, Dresden, Germany

,

Felix Häberlin

⁷Frauenklinik, Kantonspital St. Gallen, St. Gallen, Switzerland

,

Melanie Henes

⁸Frauenklinik, Universitätsklinikum Tübingen, Tübingen, Germany

,

Jens Hirchenhain

³Frauenklinik, Universitätsklinikum Düsseldorf, Düsseldorf, Germany

,

Stephanie Hübner

⁸Frauenklinik, Universitätsklinikum Tübingen, Tübingen, Germany

,

Matthias Korell

⁹Frauenklinik, Johanna Etienne Klinikum Neuss, Neuss, Germany

,

Jan-Steffen Krüssel

³Frauenklinik, Universitätsklinikum Düsseldorf, Düsseldorf, Germany

,

Andreas Müller

¹⁰Frauenklinik, Klinikum Karlsruhe, Karlsruhe, Germany

,

Jochen Reinsberg

¹¹Frauenklinik, Universitätsklinikum Bonn, Bonn, Germany (currently at Zentrum für Gynäkologische Endokrinologie und Reproduktionsmedizin Bonn)

,

Roxana Schwab

¹²Frauenklinik, Universitätsklinikum Mainz, Mainz, Germany

,

Stephan Seitz

¹³Frauenklinik, Krankenhaus St. Josef, Universität Regensburg, Regensburg, Germany

,

Marc Sütterlin

¹⁴Frauenklinik, Universitätsklinikum Mannheim, Mannheim, Germany

,

Hans van der Ven

¹¹Frauenklinik, Universitätsklinikum Bonn, Bonn, Germany (currently at Zentrum für Gynäkologische Endokrinologie und Reproduktionsmedizin Bonn)

,

Katrin van der Ven

¹¹Frauenklinik, Universitätsklinikum Bonn, Bonn, Germany (currently at Zentrum für Gynäkologische Endokrinologie und Reproduktionsmedizin Bonn)

,

Katharina Winkler-Crepaz

²Gynäkologische Endokrinologie und Reproduktionsmedizin, Universitätsklinikum Innsbruck, Innsbruck, Austria

,

Pauline Wimberger

⁶Frauenklinik, Universitätsklinikum Dresden, Dresden, Germany

,

Michael von Wolff

¹⁵Frauenklinik, Universitätsspital Bern, Bern, Switzerland

,

Jana Liebenthron^*

³Frauenklinik, Universitätsklinikum Düsseldorf, Düsseldorf, Germany

,

Ralf Dittrich^*

¹Frauenklinik, Universitätsklinikum Erlangen, Erlangen, Germany

› Institutsangaben

Abstract

The cryopreservation of ovarian tissue with subsequent transplantation of the tissue represents an established method of fertility protection for female patients who have to undergo gonadotoxic therapy. The procedure can be performed at any point in the cycle and thus generally does not lead to any delay in oncological therapy. With the aid of this procedure, more than 130 births to date worldwide have been able to be recorded. The birth rate is currently approximately 30% and it can be assumed that this will increase through the further optimisation of the cryopreservation and surgical technique. The concept paper presented here is intended to provide guidance for managing cryopreservation and transplantation of ovarian tissue to German-speaking reproductive medicine centres.

Key words

FertiPROTEKT - fertility protection - ovarian tissue - cryopreservation - transplantation

Volltext

Referenzen

References/Literatur
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