A Novel Diels-Alder Approach To Heavily Substituted Azasugars

Kamyar Afarinkia; Akmal Bahar; Judi Neuss

doi:10.1055/s-2003-43336

LETTER

A Novel Diels-Alder Approach To Heavily Substituted Azasugars

Kamyar Afarinkia*^a, Akmal Bahar^a, Judi Neuss^b
^a Department of Chemistry, King’s College London, Strand, London, WC2R 2LS, UK
^b Celltech R&D Ltd., 208 Bath Road, Slough, Berkshire, SL1 3WE, UK
e-Mail: kamyar.afarinkia@kcl.ac.uk;

Abstract

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Abstract

Diels-Alder cycloaddition of an appropriately substituted 1,4-oxazin-2-one with vinylene carbonate followed by the chemical manipulation of the bridged bicyclic lactone cycloadduct affords a heavily functionalised azasugar ring.

Key words

Diels-Alder - cycloaddition - 2H-1,4-oxazin-2-one - azasugar

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Referenzen

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