CC BY-NC-ND 4.0 · Endosc Int Open 2018; 06(08): E984-E988
DOI: 10.1055/a-0591-2740
Original article
Owner and Copyright © Georg Thieme Verlag KG 2018

Novel triple lumen catheter for ERCP tissue diagnosis

Martin Goetz
Innere Medizin I, Universitätsklinikum Tübingen, Tübingen, Germany
,
Nisar P. Malek
Innere Medizin I, Universitätsklinikum Tübingen, Tübingen, Germany
› Author Affiliations
Further Information

Publication History

submitted 19 September 2017

accepted after revision 19 January 2018

Publication Date:
03 August 2018 (online)

Abstract

Introduction The ideal endoscopic retrograde cholangiopancreatography (ERCP) tissue sampling technique should be simple, inexpensive, and yield sufficient tissue for histology while permitting contrast-guided targeting under fluorescence and multiple passes into the bile duct. Current techniques do not fulfill these requirements comprehensively. We designed a catheter for optimized targeting of large intrabiliary biopsies.

Methods A 3.5-mm sterile, single-use prototype catheter was developed, with three independent lumina extending continuously to the distal tip for three distinct functions to be available simultaneously: passage of large volume biopsy forceps (1.8 mm), wire guidance (0.035″), and contrast injection.

Results First clinical use in five patients (four transpapillary, one percutaneous access) allowed good intrabiliary manipulation in 4/5 patients. Contrast-guided sampling provided adequate specimens. No adverse events were noted.

Discussion Technical aspects and preliminary clinical data for the novel triple lumen biopsy catheter are encouraging. The catheter allowed wire guidance and contrast application to guide sampling of larger pieces of tissue. In perspective, the working channel could host any accessory for targeted intrabiliary diagnosis and therapy, and catheter use is not limited to bile ducts.