Abstract
Background and study aims For early esophageal adenocarcinoma, endoscopic resection is an accepted curative
treatment with an excellent long-term prognosis. Case series from Japan have reported
endoscopic resection of residual esophageal squamous cell carcinoma after chemoradiotherapy.
This is the first report describing endoscopic resection of residual esophageal adenocarcinoma
after chemoradiotherapy. Two patients with advanced esophageal adenocarcinoma had
been treated with chemoradiotherapy because comorbidity precluded esophageal resection.
When residual tumor was observed endoscopically, complete remission was achieved by
salvage endoscopic therapy alone or in combination with argon plasma coagulation (APC).
Both patients achieved long-term sustained remission and died of non-tumor-related
causes.