Endoscopy 2019; 51(04): 360-364
DOI: 10.1055/a-0856-6845
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

Detachable string magnetically controlled capsule endoscopy for complete viewing of the esophagus and stomach

Yi-Zhi Chen*
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Jun Pan*
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Yuan-Yuan Luo
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Xi Jiang
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Wen-Bin Zou
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Yang-Yang Qian
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Wei Zhou
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Xiao Liu
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Zhao-Shen Li
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
,
Zhuan Liao
National Clinical Research Center for Digestive Diseases; Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China
› Author Affiliations
Further Information

Publication History

submitted 07 September 2018

accepted after revision 28 January 2019

Publication Date:
01 March 2019 (eFirst)

Abstract

Background Esophageal capsule endoscopy is reported to be insufficiently accurate to replace esophagogastroduodenoscopy (EGD) because the passage of the capsule through the esophagus is passive and precludes a thorough investigation. We developed a modified capsule endoscopy technique, called detachable string magnetically controlled capsule endoscopy (DS-MCE), and performed a pilot study to assess the feasibility and safety of this novel technique.

Methods 4 healthy volunteers and 21 patients with suspected esophageal disease first underwent DS-MCE followed by EGD within 1 week. Outcomes included technical success of DS-MCE, adverse events, discomfort, and diagnostic accuracy.

Results DS-MCE was successfully carried out in all 25 participants. No adverse events were observed. Mean overall discomfort score during DS-MCE was 0.96 (range 0 – 3). DS-MCE diagnoses were in accordance with EGD in all 25 participants. The per-patient sensitivity of DS-MCE for esophageal disease detection was 100 %. The accuracy of DS-MCE for grading esophageal varices and reflux esophagitis were 66.7 % and 100 %, respectively.

Conclusions DS-MCE was a feasible, safe, and well-tolerated method for viewing the esophagus and proceeding with gastric examination after string detachment.

* These authors contributed equally to this work.


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