Endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) using electrocautery-enhanced lumen-apposing metal stent: the easiest way to perform EUS-CDS?
30 April 2019 (eFirst)
Endoscopic ultrasound (EUS)-guided biliary drainage is an alternative to percutaneous transhepatic biliary drainage (PTBD) in patients with malignant biliary obstructions and those for whom endoscopic retrograde cholangiopancreatography (ERCP) fails or is impossible. Duodenal stenosis attributable to tumor overgrowth is a classic example of the latter situation. Although increasing evidence indicates that EUS-guided biliary drainage is superior to PTBD , only a few expert centers routinely perform the former procedure, which is technically challenging.
Recently, new lumen-apposing metal stents (LAMS) placed via electrocautery have become available; these can be used to aid EUS-guided choledochoduodenostomy (EUS-CDS). These all-in-one devices facilitate fast, safe EUS-CDS without the need for device exchange . Here, we report the case of a 60-year-old man with duodenal and biliary obstructions secondary to pancreatic head cancer ([Fig. 1 a]).
The dilated bile duct was easily visualized close to the duodenal bulb using an endoscope placed via the conventional long route ([Fig. 1 b]). After direct puncture of the bile duct using the electrocautery device (AXIOS System; Boston Scientific, Marlborough, Massachusetts, USA), the sheath was pushed toward the opposite wall of the bile duct for correct positioning of the LAMS (6 mm diameter) ([Fig. 1 c]). After locking the sheath, the distal flange was opened under EUS guidance using the dedicated stent deployment hub. The distal flange was deployed, then the sheath was gently removed until the distal flange became retracted and took a cone shape. Next, the proximal flange was deployed and the sheath was pushed to allow final stent deployment ([Fig. 1 d, e], [Video 1]). A classical duodenal stent was then deployed through the tumoral obstruction ([Fig. 1 f]).
Video 1 Endoscopic ultrasound-guided choledochoduodenstomy with electrocautery-assisted placement of a lumen-apposing metal stent (AXIOS) and duodenal stent.
Four studies on EUS-CDS using the new device have already been published    . The technical and clinical success rates are very high. Morbidity seems to be much less than that associated with classical EUS-guided biliary drainage, probably because the absence of opacification and device exchange considerably reduces the risks of biliary leakage and cholangitis. This procedure may become the standard form of EUS-guided biliary drainage in patients with distal tumoral biliary obstructions in whom ERCP fails. The procedure is simple and safe, requiring only EUS guidance. No device exchange is required. The safety features incorporated into the device will render its use very popular.
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