Potential Unconventional Medicines for the Treatment of SARS-CoV-2

Key words

antiviral drugs - pharmacology - drug research

Publikationsverlauf

Artikel online veröffentlicht:
19. Mai 2020

• References

• 1 Adem S, Eyupoglu V, Sarfraz I. et al. Identification of potent COVID-19 main protease (Mpro) inhibitors from natural polyphenols: An in silico strategy unveils a hope against corona. Preprints. 2020
• 2 Wu C, Liu Y, Yang Y. et al. Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods. Acta Pharmaceutica Sinica B. 2020
• 3 Liu S, Adewole D, Yu L. et al. Rutin attenuates inflammatory responses induced by lipopolysaccharide in an in vitro mouse muscle cell (C2C12) model. Poult Sci 2019; 98: 2756-2764
• 4 Imam F, Al-Harbi NO, Al-Harbi MM. et al. Diosmin downregulates the expression of T cell receptors, pro-inflammatory cytokines and NF-κB activation against LPS-induced acute lung injury in mice. Pharmacol Res 2015; 102: 1-11
• 5 Caly L, Druce JD, Catton MG. et al. The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro. Antiviral Research. 2020
• 6 Hoffmann M, Kleine-Weber H, Schroeder S. et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 2020; 181: 271-280
• 7 JM Lucas, Heinlein C, Kim T. et al. The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis. Cancer Discov 2014; 4: 1310-1325