Diabetische Polyneuropathie

Die Auswirkungen der distal-symmetrischen sensomotorischen Polyneuropathie (DSPN) werden noch häufig unterschätzt. Die Ergebnisse der PROTECT Follow-up Studie [1] weisen auf eine mangelnde Versorgung, Adhärenz oder Wirksamkeit hinsichtlich der DSPN-Therapie hin.

• Literatur

• 1 Ziegler D, Landgraf R, Lobmann R. et al Polyneu ropathy is inadequately treated despite increasing symptom intensity in individuals with and without diabetes (PROTECT follow-up study). J Diabetes Investig 2020 published online ahead of print, 2020 Apr 8. doi:10.1111/jdi.13267
• 2 Pop-Busui R, Boulton AJ, Feldman EL. et al Diabetic neuropathy: A position statement by the American Diabetes Association. Diabetes Care 2017; 40: 136-154 doi:10.2337/dc16-2042
• 3 Ziegler D, Papanas N, Vinik AI. et al Epidemiolo gy of polyneuropathy in diabetes and prediabetes. Handb Clin Neurol 2014; 126: 3-22 doi:10.1016/B978-0-444-53480-4.00001-1
• 4 Bongaerts BWC, Rathmann W, Heier M. et al Older subjects with diabetes and prediabetes are frequently unaware of having distal sensorimotor polyneuropathy: the KORA F4 study. Diabetes Care 2013; 36: 1141-1146 doi:10.2337/dc12-0744
• 5 Ziegler D, Landgraf R, Lobmann R. et al Painful and painless neuropathies are distinct and largely undiagnosed entities in subjects participating in an educational initiative (PROTECT study). Diabetes Res Clin Pract 2018; 139: 147-154 doi:10.1016/j.diabres.2018.02.043
• 6 Meisinger C, Bongaerts BWC, Heier M. et al Neuro pathic pain is not adequately treated in the older general population: Results from the KORA F4 survey. Pharmacoepidemiol Drug Saf 2018; 27: 806-814 doi:10.1002/pds.4559
• 7 Daousi C, Benbow SJ, Woodward A. et al The natur al history of chronic painful peripheral neuropathy in a community diabetes population. Diabet Med 2006; 23: 1021-1024 doi:10.1111/j.1464-5491.2006.01904.x