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Modified endoscopic vacuum therapy in the management of a duodenal transmural defect
Gastrointestinal (GI) transmural defects are associated with high rates of morbidity and mortality  . Endoscopic vacuum therapy (EVT) has become a safe and effective tool for intraluminal treatment of these conditions, as it promotes changes in perfusion, microdeformation and macrodeformation of the tissue, and decreases bacterial contamination and local edema to facilitate healing. However, the high cost of the sponge system may limit widespread use of this technique . In this video, we describe a cost-effective modified EVT for the treatment of transmural GI defects ([Fig. 1 a]).
The procedure is performed with the use of an antimicrobial incise drape, gauze, a nasogastric tube (NGT), and nylon sutures. First, the antimicrobial drape is cut to match the size of the fenestrated portion of the NGT. Several holes are then made in the drape using a needle. Next, the gauze is wrapped around the fenestrated portion of the NGT and this is covered in the antimicrobial drape. Finally, the suture is used to fix the gauze and drape to the NGT ([Fig. 1 b]).
We report the use of this modified device in a 64-year-old man with cholangiocarcinoma who had undergone right hepatectomy and presented on post-operative day 30 with sepsis and melena. Esophagogastroduodenoscopy (EGD) and computed tomography (CT) scanning showed a transmural duodenal wall defect associated with a fluid collection ([Fig. 2]). Given the patient’s clinical instability, it was decided that surgical therapy should be deferred owing to the high risk of mortality. Therefore, EVT was considered the best option for this patient. The patient was successfully treated with the modified EVT system ([Fig. 3]; [Video 1]), with the first procedure being followed by four EVT system exchanges, and he was discharged from the hospital 24 days after his initial procedure.
Video 1 Video showing how to make the modified endoscopic vacuum therapy device and its use, with subsequent exchanges performed, in the management of a patient with a duodenal transmural defect.
This novel cost-effective modified endoscopic vacuum therapy is feasible and appears to be as safe and effective as the traditional sponge EVT system in the right clinical scenario.
Endoscopy E-Videos is a free access online section, reporting on interesting cases and new techniques in gastroenterological endoscopy. All papers include a high
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29 May 2020 (online)
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- 3 de Moura DTH, de Moura BFBH, Manfredi MA. et al. Role of endoscopic vacuum therapy in the management of gastrointestinal transmural defects. World J Gastrointest Endosc 2019; 11: 329-344