Endoscopy 2021; 53(05): 517-521
DOI: 10.1055/a-1189-9550
Innovations and brief communications

Double-balloon endoscopy facilitates efficient endoscopic resection of duodenal and jejunal polyps in patients with familial adenomatous polyposis

Mariko Sekiya
1  Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan
,
Hirotsugu Sakamoto
1  Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan
,
Tomonori Yano
1  Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan
,
Shoko Miyahara
1  Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan
,
Manabu Nagayama
1  Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan
,
Yasutoshi Kobayashi
1  Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan
,
Satoshi Shinozaki
1  Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan
2  Shinozaki Medical Clinic, Utsunomiya, Japan
,
Keijiro Sunada
1  Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan
,
Alan Kawarai Lefor
3  Department of Surgery, Jichi Medical University, Shimotsuke, Japan
,
Hironori Yamamoto
1  Department of Medicine, Division of Gastroenterology, Jichi Medical University, Shimotsuke, Japan
› Author Affiliations

Abstract

Background Many patients with familial adenomatous polyposis (FAP) have adenomatous polyps of the duodenum and the jejunum. We aimed to elucidate the long-term outcomes after double-balloon endoscopy (DBE)-assisted endoscopic resection of duodenal and jejunal polyps in patients with FAP.

Methods We retrospectively reviewed patients who underwent more than two sessions of endoscopic resection using DBE from August 2004 to July 2018.

Results A total of 72 DBEs were performed in eight patients (median age 30 years, range 12–53; 1.4 DBE procedures/patient-year) during the study period, and 1237 polyps were resected. The median observation period was 77.5 months (range 8–167). There were 11 adverse events, including seven delayed bleeds and four episodes of acute pancreatitis. No delayed bleeding occurred after cold polypectomy. Although, in one patient, one endoscopically resected duodenal polyp was diagnosed as being intramucosal carcinoma, none of the patients developed an advanced duodenal or jejunal cancer during the study period.

Conclusions Endoscopic resection of duodenal and jejunal polyposis using DBE in patients with FAP can be performed safely, efficiently, and effectively.



Publication History

Received: 29 December 2019

Accepted: 28 May 2020

Publication Date:
28 May 2020 (online)

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