Int J Sports Med 2021; 42(01): 3-18
DOI: 10.1055/a-1198-5496

Mapping Robust Genetic Variants Associated with Exercise Responses

Javier Alvarez-Romero
1   Institute for Health and Sport, Victoria University, Melbourne, Australia
Sarah Voisin
1   Institute for Health and Sport, Victoria University, Melbourne, Australia
Nir Eynon
1   Institute for Health and Sport, Victoria University, Melbourne, Australia
2   MCRI, Murdoch Childrens Research Institute, Parkville, Australia
1   Institute for Health and Sport, Victoria University, Melbourne, Australia
› Author Affiliations


This review summarised robust and consistent genetic variants associated with aerobic-related and resistance-related phenotypes. In total we highlight 12 SNPs and 7 SNPs that are robustly associated with variance in aerobic-related and resistance-related phenotypes respectively. To date, there is very little literature ascribed to understanding the interplay between genes and environmental factors and the development of physiological traits. We discuss future directions, including large-scale exercise studies to elucidate the functional relevance of the discovered genomic markers. This approach will allow more rigour and reproducible research in the field of exercise genomics.

Publication History

Received: 24 January 2020

Accepted: 01 June 2020

Article published online:
21 July 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

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