COVID-19 and endoscopic management of superficial gastrointestinal neoplastic lesions: a multinational cross-sectional survey
Introduction We aimed to report the impact of the pandemic lockdown period on the treatment and prognosis of superficial gastrointestinal neoplastic lesions.
Methods A survey was completed by 11 centers from four continents regarding postponements during the early lockdown period of the pandemic, and the same period in 2019.
Results In 2020, 55 % of the scheduled procedures were deferred, which was 11 times higher than in 2019; the main reasons were directly related to COVID-19. In countries that were highly affected, this proportion rose to 76 % vs. 26 % in those where there was less impact. Despite the absolute reduction, the relative distribution in 2019 vs. 2020 was similar, the only exception being duodenal lesions (affected by a 92 % reduction in mucosectomies). Although it is expected that the majority of postponements will not affect the stage (based on the results from biopsies and/or endoscopic appearance), 3 % of delayed procedures will probably require surgery.
Conclusions The lockdown period caused by the SARS-CoV-2 pandemic led to a substantial reduction in the number of endoscopic resections for neoplastic lesions. Nevertheless, based on clinical judgment, the planned median delay will not worsen the prognosis of the affected patients.
Eingereicht: 23. Mai 2020
Angenommen: 11. August 2020
11. August 2020 (online)
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- 1 WHO Director-General’s opening remarks at the media briefing on COVID-19. Available at (Accessed 2 September 2020): https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---29-april-2020
- 2 Heymann DL, Shindo N. WHO Scientific and Technical Advisory Group for Infectious Hazards. COVID-19: What is next for public health?. Lancet 2020; 395: 542-545
- 3 Zhang H, Kang Z, Gong H. et al. Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process. Gut 2020; DOI: 10.1136/ gutjnl-2020-320953.
- 4 Lin L, Jiangx X, Zhang Z. et al. Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut 2020; 69: 997-1001
- 5 Gu J, Han B, Wang J. COVID-19: Gastrointestinal manifestations and potential fecal-oral transmission. Gastroenterology 2020; 158: 1518-1519
- 6 Gralnek IM, Hassan C, Beilenhoff U. et al. ESGE and ESGENA Position Statement on Gastrointestinal Endoscopy and the COVID-19 Pandemic. Endoscopy 2020; 52: 483-490
- 7 WHO situation report – 95. Available at (Accessed 2 September 2020): www.who.int/docs/default-source/coronaviruse/situation-reports/20200424-sitrep-95-covid-19.pdf?sfvrsn=e8065831_4
- 8 The Government of the Hong Kong Special Administrative Region. Latest Situation of Coronavirus Disease (COVID-19) in Hong Kong. Available at (Accessed: 4 September 2020): https://chp-dashboard.geodata.gov.hk/covid-19/en.html
- 9 Repici A, Pace F, Gabbiadini R. et al. Endoscopy units and the COVID-19 outbreak: a multi-center experience from Italy. Gastroenterology 2020; 159: 363-366