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Cerebral Imaging in Patients with COVID-19 and Neurological Symptoms: First Experience from two University Hospitals in Northern GermanyArticle in several languages: English | deutsch
Purpose To describe findings on cerebral imaging in patients with COVID-19 and neurological symptoms at two German university hospitals.
Materials and Methods Patients with COVID-19 and neurological symptoms and cerebral imaging (CT or MRI) were included. A chart review regarding neurological symptoms, COVID-19 and imaging findings was conducted.
Results 12 patients (4 females, age 68 ± 12 years) could be included. Three patients had acute findings. Two patients had acute and subacute cerebral ischemia, one patient had additional intracranial hemorrhages and presumed central pontine myelinolysis. One patient had presumed COVID-19-associated pansinusitis.
Conclusion Findings on cerebral imaging in patients with COVID-19 are uncommon and nonspecific. However, cerebral ischemia is regularly encountered and patients should be evaluated for stroke symptoms.
Approx. 20 % of patients with COVID-19 develop neurological symptoms.
Findings on cerebral imaging in patients with COVID-19 are heterogeneous and nonspecific.
The most common findings are cerebral ischemia and hemorrhages.
Jensen-Kondering U, Neumann A, Margraf N et al. Cerebral Imaging in Patients with COVID-19 and Neurological Symptoms: First Experience from two University Hospitals in Northern Germany. Fortschr Röntgenstr 2021; 193: 667 – 671
Received: 18 July 2020
Accepted: 04 September 2020
19 November 2020 (online)
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- 1 Guan W, Ni Z, Hu Y. et al. Clinical characteristics of coronavirus disease 2019 in China. New England Journal of Medicine 2020; 382: 1708-1720
- 2 Puelles VG, Lütgehetmann M, Lindenmeyer MT. et al. Multiorgan and Renal Tropism of SARS-CoV-2. N Engl J Med 2020; DOI: 10.1056/NEJMc2011400.
- 3 Mao L, Jin H, Wang M. et al. Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China. JAMA Neurol 2020; 77 (06) 683-690
- 4 Tsai LK, Hsieh ST, Chang YC. Neurological manifestations in severe acute respiratory syndrome. Acta Neurol Taiwan 2005; 14: 113-119
- 5 Kim JE, Heo JH, Kim HO. et al. Neurological Complications during Treatment of Middle East Respiratory Syndrome. J Clin Neurol 2017; 13: 227-233
- 6 Helms J, Kremer S, Merdji H. et al. Neurologic Features in Severe SARS-CoV-2 Infection. N Engl J Med 2020; 382 (23) 2268-2270
- 7 Kandemirli SG, Dogan L, Sarikaya ZT. et al. Brain MRI Findings in Patients in the Intensive Care Unit with COVID-19 Infection. Radiology 2020; 297: 201697
- 8 Radmanesh A, Raz E, Zan E. et al. Brain Imaging Use and Findings in COVID-19: A Single Academic Center Experience in the Epicenter of Disease in the United States. AJNR Am J Neuroradiol 2020; DOI: 10.3174/ajnr.A6610.
- 9 Escalard S, Maïer B, Redjem H. et al. Treatment of Acute Ischemic Stroke due to Large Vessel Occlusion With COVID-19: Experience From Paris. Stroke 2020; DOI: STROKEAHA120030574.
- 10 Yaghi S, Ishida K, Torres J. et al. SARS-CoV-2 and Stroke in a New York Healthcare System. Stroke 2020; 51 (07) 2002-2011
- 11 Benussi A, Pilotto A, Premi E. et al. Clinical characteristics and outcomes of inpatients with neurologic disease and COVID-19 in Brescia, Lombardy, Italy. Neurology 2020; DOI: 10.1212/WNL.0000000000009848.
- 12 Belani P, Schefflein J, Kihira S. et al. COVID-19 Is an Independent Risk Factor for Acute Ischemic Stroke. AJNR Am J Neuroradiol 2020; DOI: 10.3174/ajnr.A6650.
- 13 Wu Y, Xu X, Chen Z. et al. Nervous system involvement after infection with COVID-19 and other coronaviruses. Brain Behav Immun 2020; DOI: S0889-1591(20)30357-3.
- 14 Nicholson P, Alshafai L, Krings T. Neuroimaging Findings in Patients with COVID-19. AJNR Am J Neuroradiol 2020; DOI: 10.3174/ajnr.A6630.
- 15 Solomon IH, Normandin E, Bhattacharyya S. et al. Neuropathological Features of COVID-19. N Engl J Med 2020; DOI: NEJMc2019373.