Drug Res (Stuttg) 2021; 71(06): 317-325
DOI: 10.1055/a-1302-7649
Original Article

Synthesis of N2, N6-bis(5-methylthiazol-2-yl)pyridine-2,6-dicarboxamide fluoroscent sensor for detection of Cu2+ and Ni2+ Ions

Anuroop Kumar
1   Department of Chemistry, Meerut College, Meerut, India
Netrapal Singh
2   Department of Chemistry, D. D. U Gorakhpur University, Gorakhpur, India
Mordhwaj Kumar
3   ACBR, North Campus, University of Delhi, Delhi, India
Uma Agarwal
1   Department of Chemistry, Meerut College, Meerut, India
› Author Affiliations


This article reports an amide based Chemosensor used for selective detection of divalent Cu+2 and Ni+2 ions via Fluorescence turn off. The selective sensing ability of Chemosensor was investigated in presence of different metal ions Mg2+, Ag+, Fe2+, K+, Cu2+, Ni2+, Hg2+, Pb2+, Mn2+, Pd2+, Cd2+ and Mn3+ as competitive ions. The receptor i. e. Chemosensor formed complexes with metal ions in 1:1 stoichiometric ratio. The detection limit and binding constant calculated as 1.92×10–4 and 1.4×10–4 M and 2.16×103 M−1 and 3.09×103 M−1 for Cu2+ and Ni2+ions respectively. The complexes were characterized by UV/visible, FT-IR, 13C NMR and 1H NMR spectroscopy. Further the structure and Crystallinity were calculated by P-XRD spectral analysis. The crystallinity found to be 65.27 and 67.87% respectively

Supplementary Material

Publication History

Received: 27 August 2020

Accepted: 26 October 2020

Article published online:
22 April 2021

© 2021. Thieme. All rights reserved.

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