Handekzem – Gleiche Therapie für alle Formen?^[*]

Zusammenfassung

Es gibt nicht einen einzigen Typ des chronischen Handekzems (CHE) – weder morphologisch noch immunologisch. Schutz und Präventionsmaßnahmen können für alle Typen des CHE definiert werden. Die Therapie muss passen und zielgerichtet sein. Einige Therapien können jedoch für alle Typen des Handekzems angeboten werden wie topische Kortikosteroide, Calcineurinantagonisten, UV-Therapie und Alitretinoin, ggf. auch Dupilumab, was in größeren Studien untersucht werden sollte. Die Wahrnehmung des Handekzems sollte gerade in Zeiten der Irritation durch Desinfektion der Hände erhöht werden, damit Prävention und frühzeitige Therapie erfolgen können.

Abstract

There is not just one type of chronic hand dermatitis (CHD) – neither morphologically nor immunologically. Protective measures must be used for all types of CHD. Therapies have to aim for the individual type of dermatitis. Nevertheless, some therapies are generally used for CHD like topical corticosteroids, calcineurin inhibitors, ultraviolet therapies and alitretinoin, probably dupilumab as well. The latter should be studied in clinical controlled trials for CHD. Awareness of CHD should be increased especially in times of irritation of the hands by desinfection. Prevention and early therapy are mandatory.

^* Vortrag anlässlich der Korting-Gedächtnisvorlesung, 6. November 2020 beim digitalen Symposium anlässlich des 25-jährigen Bestehens der GD, Gesellschaft für Dermopharmazie e. V.

Publication History

Article published online:
14 April 2021

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