CC BY-NC-ND 4.0 · Laryngorhinootologie 2021; 100(S 01): S1-S30
DOI: 10.1055/a-1347-4171
Referat

Seltene Erkrankungen des Mittelohres und der lateralen Schädelbasis

Article in several languages: deutsch | English
Nora M. Weiss
1   Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie „Otto Körner“ der Universitätsmedizin Rostock, Deutschland
› Author Affiliations

Zusammenfassung

Otalgie, Otorrhoe, Tinnitus und Hörminderung zählen zu den häufigsten ohrbezogenen Symptomen, die zum Aufsuchen eines Hals-Nasen-Ohrenarztes führen. Weiterhin spielen Gleichgewichtsstörungen und Affektionen der Hirnnervenfunktion für eine Konsultation eine Rolle. In großen akademischen Zentren, aber auch in der HNO-ärztlichen Grundversorgung kommt der Erkennung von seltenen Erkrankungen des Mittelohres und der lateralen Schädelbasis eine zentrale Rolle zu, da sie häufig eine interdisziplinäre Zusammenarbeit erfordern um die korrekte Diagnose zu stellen und eine adäquate Behandlung zu initiieren. Die folgende Arbeit gibt einerseits eine Übersicht über seltene Formen von osteologischen, neoplastischen, hämatologischen, autoimmunologischen und infektiologischen Erkrankungen sowie Fehlbildungen, die sich im Mittelohr und der lateralen Schädelbasis manifestieren können, andererseits soll ein Überblick über internistische Erkrankungen gegeben werden, deren Manifestation im Mittelohr selten ist.

Die Kenntnis von seltenen Erkrankungen des Mittelohrs und der Schädelbasis ist für die Qualitätssicherung in der Patientenversorgung und insbesondere auch bei entsprechenden chirurgischen Maßnahmen wesentlich. Insbesondere bei untypischen, komplizierten und langwierigeren Krankheitsverläufen muss an seltene Differenzialdiagnosen gedacht werden.



Publication History

Article published online:
30 April 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • Literature

  • 1 Jahrsdoerfer RA, Yeakley JW, Aguilar EA, Cole RR, Gray LC. Grading system for the selection of patients with congenital aural atresia. Am J Otol 1992; 13: 6-12
  • 2 Jahrsdoerfer RA. Congenital atresia of the ear. Laryngoscope. 1978; 88: 1-48
  • 3 Weerda H. Classification of congenital deformities of the auricle. Facial Plast Surg 1988; 5: 385-388
  • 4 Patterson ME, Linthicum FHJ. Congenital hearing impairment. Otolaryngol Clin North Am 1970; 3: 201-219
  • 5 Gerhardt HJ, Otto HD. Stapedial malformation. Acta Otolaryngol 1970; 70: 35-44
  • 6 Teunissen EB, Cremers WR. Classification of congenital middle ear anomalies. Report on 144 ears. Ann Otol Rhinol Laryngol 1993; 102: 606-612
  • 7 Fu Y, Dai P, Zhang T. The location of the mastoid portion of the facial nerve in patients with congenital aural atresia. Eur Arch Otorhinolaryngol 2014; 271: 1451-1455
  • 8 Mündnich K, Terrahe K. Missbildungen des Ohres. In: Berendes J, Link R, Zöllner F Eds. Ohr I, Band 5; Stuttgart: 1979: 1-49
  • 9 Chang SO, Min YG, Kim CS, Koh TY. Surgical management of congenital aural atresia. Laryngoscope 1994; 104: 606-611
  • 10 Gorlin R, Pindborg J, Cohen M. Oculoauriculovertebral dysplasia. In: Syndromes of the head and neck 2nd ed. New York: 1976: 546-552
  • 11 Phelps PD, Poswillo D, Lloyd GA. The ear deformities in mandibulofacial dysostosis (Treacher Collins syndrome). Clin Otolaryngol Allied Sci 1981; 6: 15-28
  • 12 Jahrsdoerfer RA, Aguilar EA, Yeakley JW, Cole RR. Treacher Collins syndrome: an otologic challenge. Ann Otol Rhinol Laryngol 1989; 98: 807-812
  • 13 Boggering B. Oto-vertebral syndrome. Fortschr Med 1975; 93: 1452-1455
  • 14 Frenzel H. Hearing Rehabilitation in Congenital Middle Ear Malformation. Adv Otorhinolaryngol 2018; 81: 32-42
  • 15 Mlynski R, Schwager K. Funktionelle Rekonstruktion bei Ohrfehlbildungen. In: Bumm K editor. Korrektur und Rekonstruktion der Ohrmuschel 1st ed.. Saarbrücken; 2016: 275-291
  • 16 Beutner D, Delb W, Frenzel H, Hoppe U, Hüttenbrink KB, Mlynski R. et al. Guideline “Implantable hearing aids”– short version: German S2k guideline of the Working Group of German-Speaking Audiologists, Neurootologists and Otologists (ADANO), of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (DGHNO) in colla. HNO 2018; 66: 71-76
  • 17 Thompson H, Ohazama A, Sharpe PT, Tucker AS. The origin of the stapes and relationship to the otic capsule and oval window. Dev Dyn 2012; 241: 1396-1404
  • 18 Herther C, Schindler RA. Mondini’s dysplasia with recurrent meningitis. Laryngoscope 1985; 95: 655-658
  • 19 Tandon S, Singh S, Sharma S, Lahiri AK. Use of Intrathecal Fluorescein in Recurrent Meningitis after Cochlear Implantation. Vol. 28 Iranian journal of otorhinolaryngology. Iran 2016; 221-226
  • 20 Weiss NM, Andus I, Schneider A, Langner S, Schroder S, Schraven SP. et al. Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation. J Vis Exp. 2020
  • 21 Frenzel H, Sprinzl G, Widmann G, Petersen D, Wollenberg B, Mohr C. Grading system for the selection of patients with congenital aural atresia for active middle ear implants. Neuroradiology 2013; 55: 895-911
  • 22 Schuknecht H. Gavin Livingstone Memorial Lecture. Anatomical variants and anomalies of surgical significance. J Laryngol Otol 1971; 85: 1238-1241
  • 23 Hogg ID, Stephens CB, Arnold GE. Theoretical anomalies of the stapedial artery. Ann Otol Rhinol Laryngol 1972; 81: 860-870
  • 24 Lyu A-R, Park SJ, Kim D, Lee HY, Park Y-H. Radiologic features of vascular pulsatile tinnitus – suggestion of optimal diagnostic image workup modalities. Acta Otolaryngol 2018; 138: 128-134
  • 25 Hofmann E, Behr R, Neumann-Haefelin T, Schwager K. Pulsatile tinnitus: imaging and differential diagnosis. Dtsch Arztebl Int 2013; 110: 451-458
  • 26 Friedmann DR, Eubig J, McGill M, Babb JS, Pramanik BK, Lalwani AK. Development of the jugular bulb: a radiologic study. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc [and] Eur Acad. Otol Neurotol 2011; 32: 1389-1395
  • 27 Merchant SN, Rosowski JJ. Conductive hearing loss caused by third-window lesions of the inner ear. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc [and] Eur Acad. Otol Neurotol 2008; 29: 282-289
  • 28 Sayit AT, Gunbey HP, Fethallah B, Gunbey E, Karabulut E. Radiological and audiometric evaluation of high jugular bulb and dehiscent high jugular bulb. J Laryngol Otol 2016; 130: 1059-1063
  • 29 Koo YH, Lee JY, Lee JD, Hong HS. Dehiscent high-riding jugular bulb presenting as conductive hearing loss: A case report. Medicine (Baltimore) 2018; 97: e11067
  • 30 Friedmann DR, Le BT, Pramanik BK, Lalwani AK. Clinical spectrum of patients with erosion of the inner ear by jugular bulb abnormalities. Laryngoscope 2010; 120: 365-372
  • 31 Maroldi R, Farina D, Palvarini L, Marconi A, Gadola E, Menni K. et al. Computed tomography and magnetic resonance imaging of pathologic conditions of the middle ear. Eur J Radiol 2001; 40: 78-93
  • 32 Kaftan S, Sarach V, Kahle G. Vascular structure in the middle ear. Aberrant course of the internal carotid artery in the left tympanic membrane. HNO 2002; 50: 864-865
  • 33 Heimlich F, Dörfler A, Wallner F. An aberrant course of the internal carotid artery through the middle ear. HNO 1999; 47: 986-989
  • 34 Sun W, Germans MR, Sebök M, Fierstra J, Kulcsar Z, Keller A. et al. Outcome Comparison Between Surgically Treated Brain Arteriovenous Malformation Hemorrhage and Spontaneous Intracerebral Hemorrhage. World Neurosurg 2020; 139: e807-e811
  • 35 Mohr JP, Overbey JR, Hartmann A, Kummer von R, Al-Shahi Salman R, Kim H. et al. Medical management with interventional therapy versus medical management alone for unruptured brain arteriovenous malformations (ARUBA): final follow-up of a multicentre, non-blinded, randomised controlled trial. Lancet Neurol 2020; 19: 573-581
  • 36 Zipfel GJ, Shah MN, Refai D, Dacey RGJ, Derdeyn CP. Cranial dural arteriovenous fistulas: modification of angiographic classification scales based on new natural history data. Neurosurg Focus 2009; 26: E14
  • 37 Paget J. On a form of chronic inflammation of bones (osteitis deformans). Med Chir Trans 1877; 60: 37-64
  • 38 Paget J. Additional cases of osteitis deformans. Med Chir Trans 1882; 65: 225-236
  • 39 Mills BG, Singer FR, Weiner LP, Holst PA. Immunohistological demonstration of respiratory syncytial virus antigens in Paget disease of bone. Proc Natl Acad Sci U S A 1981; 78: 1209-1213
  • 40 Siris ES. Seeking the elusive etiology of Paget disease: a progress report. Vol. 11 Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research. United States 1996; 1599-1601
  • 41 Eekhoff EWM, Karperien M, Houtsma D, Zwinderman AH, Dragoiescu C, Kneppers ALJ. et al. Familial Paget’s disease in The Netherlands: occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations. Arthritis Rheum 2004; 50: 1650-1654
  • 42 Koller F. Über die Heredität der ostitis deformans. Helv Med Acta 1946; 13: 389-400
  • 43 Schmorl G. Über ostitis deformans Paget. Virchows Arch 1932; 283: 694-751
  • 44 Bozorg Grayeli A. Progressive hearing loss with stapes fixation [Internet]. 2006 Available from https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=3235
  • 45 Lindsay JR, Suga F. Paget’s disease and sensori-neural deafness: temporal bone histopathology of Paget’s disease. Laryngoscope 1976; 86: 1029-1042
  • 46 Nager GT. Paget’s disease of the temporal bone. Ann Otol Rhinol Laryngol 1975; 84: 1-32
  • 47 Waltner JG. Stapedectomy in Paget’s disease. Histological and clinical studies. Arch Otolaryngol 1965; 82: 355-358
  • 48 McKenna MJ, Merchant SN. 15. Disorders of Bone. In: Merchant SN, Nadol JBJ editors, Schuknechts’s Pathology of the ear 3rd ed. 2010: 715-774
  • 49 Khetarpal U, Schuknecht HF. In search of pathologic correlates for hearing loss and vertigo in Paget’s disease. A clinical and histopathologic study of 26 temporal bones. Ann Otol Rhinol Laryngol Suppl 1990; 145: 1-16
  • 50 Monsell EM. The mechanism of hearing loss in Paget’s disease of bone. Laryngoscope 2004; 114: 598-606
  • 51 Monsell EM, Bone HG, Cody DD, Jacobson GP, Newman CW, Patel SC. et al. Hearing loss in Paget’s disease of bone: evidence of auditory nerve integrity. Am J Otol 1995; 16: 27-33
  • 52 Dlugaiczyk J. Seltene Erkrankungen des vestibulären Labyrinths: von Zebras, Chamäleons und Wölfen im Schafspelz (accepted for publication). Laryngorhinootologie. 2021
  • 53 Applebaum EL, Clemis JD. Temporal bone histopathology of Paget’s disease with sensorineural hearing loss and narrowing of the internal auditory canal. Laryngoscope 1977; 87: 1753-1759
  • 54 Kösling S, Plontke SK, Bartel S. Imaging of otosclerosis. Rofo. 2020
  • 55 Sillence DO, Senn A, Danks DM. Genetic heterogeneity in osteogenesis imperfecta. J Med Genet 1979; 16: 101-116
  • 56 Sillence DO, Rimoin DL, Danks DM. Clinical variability in osteogenesis imperfecta-variable expressivity or genetic heterogeneity. Birth Defects Orig Artic Ser 1979; 15: 113-129
  • 57 Armstrong BW. Stapes surgery in patients with osteogenesis imperfecta. Ann Otol Rhinol Laryngol 1984; 93: 634-635
  • 58 Garretsen TJ, Cremers CW. Stapes surgery in osteogenesis imperfecta: analysis of postoperative hearing loss. Ann Otol Rhinol Laryngol 1991; 100: 120-130
  • 59 Patterson CN, Stone HB. Stapedectomy in Van der Hoeve’s syndrome. Laryngoscope 1970; 80: 544-558
  • 60 Opheim O. Loss of hearing following the syndrome of Van der Hoeve-de Kleyn. Acta Otolaryngol 1968; 65: 337-344
  • 61 Sinder BP, Novak S, Wee NKY, Basile M, Maye P, Matthews BG. et al. Engraftment of skeletal progenitor cells by bone-directed transplantation improves osteogenesis imperfecta murine bone phenotype. Stem Cells 2020; 38: 530-541
  • 62 Lee LR, Peacock L, Ginn SL, Cantrill LC, Cheng TL, Little DG. et al. Bone Marrow Transplantation for Treatment of the Col1a2(+/G610C) Osteogenesis Imperfecta Mouse Model. Calcif Tissue Int 2019; 104: 426-436
  • 63 Gotherstrom C, Westgren M, Shaw SWS, Astrom E, Biswas A, Byers PH. et al. Pre- and postnatal transplantation of fetal mesenchymal stem cells in osteogenesis imperfecta: a two-center experience. Stem Cells Transl Med 2014; 3: 255-264
  • 64 Perosky JE, Khoury BM, Jenks TN, Ward FS, Cortright K, Meyer B. et al. Single dose of bisphosphonate preserves gains in bone mass following cessation of sclerostin antibody in Brtl/+ osteogenesis imperfecta model. Bone 2016; 93: 79-85
  • 65 Cosman F, Crittenden DB, Adachi JD, Binkley N, Czerwinski E, Ferrari S. et al. Romosozumab Treatment in Postmenopausal Women with Osteoporosis. N Engl J Med 2016; 375: 1532-1543
  • 66 Bacon S, Crowley R. Developments in rare bone diseases and mineral disorders. Ther Adv Chronic Dis 2018; 9: 51-60
  • 67 Weil A. Pubertas praecox und Knochenbrüchigkeit.In: Pubertas praecox und Knochenbrüchigkeit. 1st ed. Klin: Wschr; 1922: 2114–2115
  • 68 Albright F, Butler A, Hampton A, Smith P. Syndrome characterized by osteitis fibrosa disseminata, areas of pigmentation and endocrine dysfunction, with precocious puberty in females. N Engl J Med 1937; 216: 727-746
  • 69 Marie PJ. Cellular and molecular basis of fibrous dysplasia. Histol Histopathol 2001; 16: 981-988
  • 70 Weinstein LS. G(s)alpha mutations in fibrous dysplasia and McCune-Albright syndrome. J Bone Miner Res. 2006: 21P120-4
  • 71 Cheng MH, Chen YR. Malignant fibrous histiocytoma degeneration in a patient with facial fibrous dysplasia. Ann Plast Surg 1997; 39: 638-642
  • 72 Van Rossem C, Pauwels P, Somville J, Camerlinck M, Bogaerts P, Van Schil PE. Sarcomatous degeneration in fibrous dysplasia of the rib cage. Ann Thorac Surg 2013; 96: e89-e90
  • 73 Yabut SMJ, Kenan S, Sissons HA, Lewis MM. Malignant transformation of fibrous dysplasia. A case report and review of the literature. Clin Orthop Relat Res 1988; 228: 281-289
  • 74 Hartley I, Zhadina M, Collins MT, Boyce AM. Fibrous Dysplasia of Bone and McCune-Albright Syndrome: A Bench to Bedside Review. Calcif Tissue Int 2019; 104: 517-529
  • 75 Pritchard JE. Fibrous dysplasia of the bones. Am J Med Sci 1951; 222: 313-332
  • 76 Cleiren E, Benichou O, Van Hul E, Gram J, Bollerslev J, Singer FR. et al. Albers-Schonberg disease (autosomal dominant osteopetrosis, type II) results from mutations in the ClCN7 chloride channel gene. Hum Mol Genet 2001; 10: 2861-2867
  • 77 de Vernejoul MC, Benichou O. Human osteopetrosis and other sclerosing disorders: recent genetic developments. Calcif Tissue Int 2001; 69: 1-6
  • 78 Stark Z, Savarirayan R. Osteopetrosis. Orphanet J Rare Dis 2009; 4: 5
  • 79 Myers EN, Stool S. The temporal bone in osteopetrosis. Arch Otolaryngol 1969; 89: 460-469
  • 80 Wong ML, Balkany TJ, Reeves J, Jafek BW. Head and neck manifestations of malignant osteopetrosis. Otolaryngology 1978; 86 ORL 585-594
  • 81 Dozier TS, Duncan IM, Klein AJ, Lambert PR, Key LLJ. Otologic manifestations of malignant osteopetrosis. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc [and] Eur Acad. Otol Neurotol 2005; 26: 762-766
  • 82 Coccia PF, Krivit W, Cervenka J, Clawson C, Kersey JH, Kim TH. et al. Successful bone-marrow transplantation for infantile malignant osteopetrosis. N Engl J Med 1980; 302: 701-708
  • 83 Hamersma H. Osteopetrosis (Marble bone disease) of the temporal bone. Laryngoscope 1970; 80: 1518-1539
  • 84 Jones MD, Mulcahy ND. Osteopathia striata, osteopetrosis, and impaired hearing. A case report. Arch Otolaryngol 1968; 87: 116-118
  • 85 Milroy CM, Michaels L. Temporal bone pathology of adult-type osteopetrosis. Arch Otolaryngol Head Neck Surg 1990; 116: 79-84
  • 86 Yarington CTJ, Sprinkle PM. Facial palsy in osteopetrosis. Relief by endotemporal decompression. JAMA 1967; 202: 549
  • 87 Hamersma H, Hofmeyr L. Too much bone: the middle ear in sclerosing bone dysplasias. Adv Otorhinolaryngol 2007; 65: 61-67
  • 88 Schmitz L, Favara BE. Nosology and pathology of Langerhans cell histiocytosis. Hematol Oncol Clin North Am 1998; 12: 221-246
  • 89 Valladeau J, Ravel O, Dezutter-Dambuyant C, Moore K, Kleijmeer M, Liu Y. et al. Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Immunity 2000; 12: 71-81
  • 90 Greenberger JS, Crocker AC, Vawter G, Jaffe N, Cassady JR. Results of treatment of 127 patients with systemic histiocytosis. Medicine (Baltimore) 1981; 60: 311-338
  • 91 Smith DG, Nesbit MEJ, D’Angio GJ, Levitt SH. Histiocytosis X: role of radiation therapy in management with special reference to dose levels employed. Radiology 1973; 106: 419-422
  • 92 Sims DG, Histiocytosis X. follow-up of 43 cases. Arch Dis Child 1977; 52: 433-440
  • 93 Arceci RJ, Brenner MK, Pritchard J. Controversies and new approaches to treatment of Langerhans cell histiocytosis. Hematol Oncol Clin North Am 1998; 12: 339-357
  • 94 McCaffrey TV, McDonald TJ. Histiocytosis X of the ear and temporal bone: review of 22 cases. Laryngoscope 1979; 89: 1735-1742
  • 95 Tos M. A survey of Hand-Schuller-Christian’s disease in otolaryngology. Acta Otolaryngol 1966; 62: 217-228
  • 96 Schuknecht HF, Perlman HB. Hand-Schuller-Christian disease and eosinophilic granuloma of the skull. Ann Otol Rhinol Laryngol 1948; 57: 643-676
  • 97 Dingley AR. Eosinophil granuloma of the temporal bone. J Laryngol Otol 1952; 66: 285-287
  • 98 Falkinburg LW, Littleton TR, Hunt RR, Horwitz M. Bilateral eosinophilic granulomas of the mastoid processes. Report of a case in a two-year-old boy, with review. AMA Arch Otolaryngol 1959; 70: 292-296
  • 99 Martin TH. Solitary eosinophilic granuloma of the temporal bone. A case report. Laryngoscope 1969; 79: 2165-2171
  • 100 Sweet RM, Kornblut AD, Hyams VJ. Eosinophilic granuloma in the temporal bone. Laryngoscope 1979; 89: 1545-1552
  • 101 Cunningham MJ, Curtin HD, Jaffe R, Stool SE. Otologic manifestations of Langerhans’ cell histiocytosis. Arch Otolaryngol Head Neck Surg 1989; 115: 807-813
  • 102 Chisolm JJ. Otorhinologic aspects of Hand-Schuller-Christian’s disease. Laryngoscope 1954; 64: 486-496
  • 103 Levy R, Sarfaty SM, Schindel J. Eosinophilic granuloma of the temporal bone. Two cases with bilateral involvement. Arch Otolaryngol 1980; 106: 167-171
  • 104 Hudson WR, Kenan PD. Otologic manifestations of histiocytosis X. Laryngoscope 1969; 79: 678-693
  • 105 Schuknecht HF. Histiocytosis X Otolaryngol Head Neck Surg (1979). 1980; 88: 544-547
  • 106 Levine S, Stone J. Pathogenesis of Wegener’s granulomatosis and related vasculitides. 2007 p. www.uptodate.com version 15.3.
  • 107 Calonius IH, Christensen CK. Hearing impairment and facial palsy as initial signs of Wegener’s granulomatosis. J Laryngol Otol 1980; 94: 649-657
  • 108 Karmody CS. Wegener’s granulomatosis: presentation as an otologic problem. Otolaryngology 1978; 86 ORL 573-584
  • 109 Kornblut AD, Wolff SM, deFries HO, Fauci AS. Wegener’s granulomatosis. Otolaryngol Clin North Am 1982; 15: 673-683
  • 110 Blatt I, Lawrence M. otologic manifestations of fatal granulomatosis of respiratory tract: Lethal midline granuloma – Wegener’s granulomatosis. Arch Otolaryngol 1961; 73: 639-643
  • 111 Ohtani I, Baba Y, Suzuki C, Sakuma H, Kano M. Temporal bone pathology in Wegener’s granulomatosis. Fukushima J Med Sci 2000; 46: 31-39
  • 112 McDonald TJ, DeRemee RA. Wegener’s granulomatosis. Laryngoscope 1983; 93: 220-231
  • 113 Amiraraghi N, Robertson S, Iyer A. Primary otological manifestations of granulomatosis with polyangiitis: a case series. J Laryngol Otol 2015; 129: 179-182
  • 114 Bacciu A, Bacciu S, Mercante G, Ingegnoli F, Grasselli C, Vaglio A. et al. Ear, nose and throat manifestations of Churg-Strauss syndrome. Acta Otolaryngol 2006; 126: 503-509
  • 115 Rahne T, Plontke S, Keyßer G. Vasculitis and the ear: a literature review. Curr Opin Rheumatol 2020; 32: 47-52
  • 116 Ishiyama A, Canalis RF. Otological manifestations of Churg-Strauss syndrome. Laryngoscope 2001; 111: 1619-1624
  • 117 Jaksch-Wartenhorst. Polychondropathia. Wien Arch 1923; 6: 93-100
  • 118 Herman JH, Dennis MV. Immunopathologic studies in relapsing polychondritis. J Clin Invest 1973; 52: 549-558
  • 119 Michet CJ. Etiology and pathogenesis of relapsing polychondritis [Internet]. 2020 Available from https://www.uptodate.com/contents/etiology-and-pathogenesis-of-relapsing-polychondritis
  • 120 Bachor E, Blevins NH, Karmody C, Kuhnel T. Otologic manifestations of relapsing polychondritis. Review of literature and report of nine cases. Auris Nasus Larynx 2006; 33: 135-141
  • 121 McAdam LP, O’Hanlan MA, Bluestone R, Pearson CM. Relapsing polychondritis: prospective study of 23 patients and a review of the literature. Medicine (Baltimore) 1976; 55: 193-215
  • 122 Hoffman RA, Horten B. Rheumatoid nodule of the temporal bone. J Laryngol Otol 1989; 103: 768-770
  • 123 Gussen R. Atypical ossicle joint lesions in rheumatoid arthritis with sicca syndrome (Sjogren syndrome). Arch Otolaryngol 1977; 103: 284-286
  • 124 Castillo Bustamante M, Gandhi D, Kozin E, Remenschneider A. Otopathological changes of the middle and inner ear in rheumatoid arthritis. In Boston. 2019
  • 125 Swerdlow S, Campo E, Harris N. World Health Organization Classification of Tumors of Haematopoietic and Lymphoid Tissues. IARC Press; 2008
  • 126 Freedman A, Friedberg J, Aster J. Classification of the hematopoietic neoplasms [Internet]. 2020 Available from: www.uptodate.com
  • 127 Zechner G, Altmann F. The temporal bone in leukemia. Histological studies. Ann Otol Rhinol Laryngol 1969; 78: 375-387
  • 128 Schuknecht HF, Igarashi M, Chasin WD. Inner Ear Hemorrhage in Leukemia. A Case Report. Laryngoscope 1965; 75: 662-668
  • 129 Hallpike CS, Harrison MS. Clinical and pathological observations of a case of leukaemia with deafness and vertigo. J Laryngol Otol 1950; 64: 427-430
  • 130 Druss JG. Aural manifestations of leukemia. Arch Otolaryngol 1945; 42: 267-274
  • 131 Thompson DH, Ross DG, Reid JW. Granulocytic sarcoma (chloroma) initially seen as acute mastoiditis. Arch Otolaryngol 1982; 108: 388-391
  • 132 Li W, Schachern PA, Morizono T, Paparella MM. The temporal bone in multiple myeloma. Laryngoscope 1994; 104: 675-680
  • 133 LEWIS JS. Cancer of the ear: a report of 150 cases. Laryngoscope. 1960; 70: 551-579
  • 134 Broders AC. SQUAMOUS-CELL EPITHELIOMA OFTHE SKIN: A STUDY OF 256 CASES. Ann Surg 1921; 73: 141-160
  • 135 Maxwell AK, Takeda H, Gubbels SP. Primary Middle Ear Mucosal Melanoma: Case Report and Comprehensive Literature Review of 21 Cases of Primary Middle Ear and Eustachian Tube Melanoma. Ann Otol Rhinol Laryngol 2018; 127: 856-863
  • 136 Bradeley WH, Maxwell JH. Neoplasms of the middle ear and mastoid: report of fifty-four cases. Laryngoscope 1954; 64: 533-556
  • 137 Applebaum EL. Radiation-induced carcinoma of the temporal bone. Otolaryngol Head Neck Surg 1979; 87: 604-609
  • 138 Lustig LR, Jackler RK, Lanser MJ. Radiation-induced tumors of the temporal bone. Am J Otol 1997; 18: 230-235
  • 139 Ruben RJ, Thaler SU, Holzer N. Radiation induced carcinoma of the temporal bone. Laryngoscope 1977; 87: 1613-1621
  • 140 Beal DD, Lindsay JR, Ward PH. Radiation-Induced Carcinoma of the Mastoid. Arch Otolaryngol 1965; 81: 9-16
  • 141 Dehner LP, Chen KT. Primary tumors of the external and middle ear. Benign and malignant glandular neoplasms. Arch Otolaryngol 1980; 106: 13-19
  • 142 Murphy GF, Pilch BZ, Dickersin GR, Goodman ML, Nadol JBJ. Carcinoid tumor of the middle ear. Am J Clin Pathol 1980; 73: 816-823
  • 143 Thompson LDR, Nelson BL, Barnes EL. Ceruminous adenomas: a clinicopathologic study of 41 cases with a review of the literature. Am J Surg Pathol 2004; 28: 308-318
  • 144 Hyams VJ, Michaels L. Benign adenomatous neoplasm (adenoma) of the middle ear. Clin Otolaryngol Allied Sci 1976; 1: 17-26
  • 145 Zahtz GD, Zielinski B, Abramson AL. Benign adenoma of the middle ear cavity causing facial paralysis. Otolaryngol Head Neck Surg 1981; 89: 624-627
  • 146 Sudhoff H, Gehl H-B, Brasch F, Riemann R, Todt I. A rare pathology of the petrous part of the temporal bone: adenoma of the middle ear. HNO 2020; 68: 55-58
  • 147 SMITH HW, DUARTE I. Mixed tumors of the external auditory canal. Arch Otolaryngol 1962; 75: 108-113
  • 148 Baker BB, DeBlanc GB. Pleomorphic adenoma of the external auditory canal. Ear Nose Throat J 1977; 56: 81-83
  • 149 Collins RJ, Yu HC. Pleomorphic adenoma of the external auditory canal. An immunohistochemical and ultrastructural study. Cancer 1989; 64: 870-875
  • 150 Haraguchi H, Hentona H, Tanaka H, Komatuzaki A. Pleomorphic adenoma of the external auditory canal: a case report and review of the literature. J Laryngol Otol 1996; 110: 52-56
  • 151 Tsukahara K, Suzuki M, Tokashiki R, Motohashi R, Iwaya K. Pleomorphic adenoma of the external auditory canal complicated by hearing loss secondary to chronic otitis media. Auris Nasus Larynx 2006; 33: 183-186
  • 152 Markou K, Karasmanis I, Vlachtsis K, Petridis D, Nikolaou A, Vital V. Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review. Am J Otolaryngol 2008; 29: 142-146
  • 153 Mosby C. Pathology. 4th ed. Anderson W editor. 1961: 113-117
  • 154 Dong F, Gidley PW, Ho T, Luna MA, Ginsberg LE, Sturgis EM. Adenoid cystic carcinoma of the external auditory canal. Laryngoscope 2008; 118: 1591-1596
  • 155 Furstenberg A. Primary adenocarcinoma of the middle ear and mastoid. Ann Otol Rhinol Laryngol 1924; 33: 677-689
  • 156 Michel RG, Woodard BH, Shelburne JD, Bossen EH. Ceruminous gland adenocarcinoma: a light and electron microscopic study. Cancer 1978; 41: 545-553
  • 157 Jan J-C, Wang C-P, Kwan P-C, Wu S-H, Shu H-F. Ceruminous adenocarcinoma with extensive parotid, cervical, and distant metastases: case report and review of literature. Arch Otolaryngol Head Neck Surg 2008; 134: 663-666
  • 158 Doble HP, Snyder GG. Carpenter RJ 3rd. Sebaceous cell carcinoma of the external auditory canal. Otolaryngol Head Neck Surg 1981; 89: 685-688
  • 159 Ray J, Worley GA, Schofield JB, Shotton JC, al-Ayoubi A. Rapidly invading sebaceous carcinoma of the external auditory canal. J Laryngol Otol 1999; 113: 578-580
  • 160 Schuller DE, Conley JJ, Goodman JH, Clausen KP, Miller WJ. Primary adenocarcinoma of the middle ear. Otolaryngol Head Neck Surg 1983; 91: 280-283
  • 161 Glasscock ME, McKennan KX, Levine SC, Jackson CG. Primary adenocarcinoma of the middle ear and temporal bone. Arch Otolaryngol Head Neck Surg 1987; 113: 822-824
  • 162 Benecke JEJ, Noel FL, Carberry JN, House JW, Patterson M. Adenomatous tumors of the middle ear and mastoid. Am J Otol 1990; 11: 20-26
  • 163 Ramsey MJ, Nadol JBJ, Pilch BZ, McKenna MJ. Carcinoid tumor of the middle ear: clinical features, recurrences, and metastases. Laryngoscope 2005; 115: 1660-1666
  • 164 Devaney KO, Ferlito A, Rinaldo A. Epithelial tumors of the middle ear – are middle ear carcinoids really distinct from middle ear adenomas?. Acta Otolaryngol 2003; 123: 678-682
  • 165 Torske KR, Thompson LDR. Adenoma versus carcinoid tumor of the middle ear: a study of 48 cases and review of the literature. Mod Pathol an Off J United States Can Acad Pathol Inc 2002; 15: 543-555
  • 166 Wang LL, Gebhardt MC, Rainusso N. Osteosarcoma: Epidemiology, pathogenesis, clinical presentation, diagnosis, and histology [Internet]. 2009 p. www.uptodate.com version 17.2 Available from: https://www.uptodate.com/contents/osteosarcoma-epidemiology-pathogenesis-clinical-presentation-diagnosis-and-histology
  • 167 Mirabello L, Troisi RJ, Savage SA. Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer 2009; 115: 1531-43
  • 168 Papagelopoulos PJ, Galanis EC, Vlastou C, Nikiforidis PA, Vlamis JA, Boscainos PJ. et al. Current concepts in the evaluation and treatment of osteosarcoma. Orthopedics 2000; 23: 858-859
  • 169 Naufal PM. Primary sarcomas of the temporal bone. Arch Otolaryngol 1973; 98: 44-50
  • 170 Coventry MB, Dahlin DC. Osteogenic sarcoma; a critical analysis of 430 cases. J Bone Joint Surg Am 1957; 39-A: 741–57. discussion, 757–758.
  • 171 Gertner R, Podoshin L, Fradis M. Osteogenic sarcoma of the temporal bone. J Laryngol Otol 1983; 97: 627-631
  • 172 Sataloff RT, Myers DL, Spiegel JR, Roberts BR, Telian S. Total temporal bone resection for osteogenic sarcoma. Ear Nose Throat J 1988; 67: 626-627 630–632, 634 passim.
  • 173 Sharma SC, Handa KK, Panda N, Banerjee AK, Mann SB. Osteogenic sarcoma of the temporal bone. Am J Otolaryngol 1997; 18: 220-223
  • 174 Seely DR, Gates GA. Parosteal osteogenic sarcoma of the mastoid bone. Ann Otol Rhinol Laryngol 1997; 106: 729-732
  • 175 Goh YH, Chong VF, Low WK. Temporal bone tumours in patients irradiated for nasopharyngeal neoplasm. J Laryngol Otol 1999; 113: 222-228
  • 176 Isikdogan A, Buyukcelik A, Erekul S, Pamir A. De novo osteogenic sarcoma of mastoid bone. Sarcoma 2002; 6: 79-81
  • 177 Wiener ES. Head and neck rhabdomyosarcoma. Semin Pediatr Surg 1994; 3: 203-206
  • 178 Friedmann DR, Peng R, Fang Y, McMenomey SO, Roland JT, Waltzman SB. Effects of loss of residual hearing on speech performance with the CI422 and the Hybrid-L electrode. Cochlear Implants Int 2015; 16: 277-284
  • 179 Durve DV, Kanegaonkar RG, Albert D, Levitt G. Paediatric rhabdomyosarcoma of the ear and temporal bone. Clin Otolaryngol Allied Sci 2004; 29: 32-37
  • 180 Alexy Z. A case of rhabdomyosarcoma in the middle ear. Monatsschr Ohrenheilkd Laryngorhinol 1968; 102: 15-18
  • 181 Jaffe BF, Fox JE, Batsakis JG. Rhabdomyosarcoma of the middle ear and mastoid. Cancer 1971; 27: 29-37
  • 182 Karatay S. Rhabdomyosarcoma of the middle ear. Arch Otolaryngol 1949; 50: 330-334
  • 183 Myers EN, Stool S, Weltschew A. Rhabdomyosarcoma of the middle ear. Ann Otol Rhinol Laryngol 1968; 77: 949-958
  • 184 Wiatrak BJ, Pensak ML. Rhabdomyosarcoma of the ear and temporal bone. Laryngoscope 1989; 99: 1188-1192
  • 185 Hawkins DS, Anderson JR, Paidas CN, Wharam MD, Qualman SJ, Pappo AS. et al. Improved outcome for patients with middle ear rhabdomyosarcoma: a children’s oncology group study. J Clin Oncol 2001; 19: 3073-3079
  • 186 Reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones. J Bone Joint Surg Am 2007; 89: 2113-2123
  • 187 Lindbom A, Soderberg G, Spjut HJ. Primary chondrosarcoma of bone. Acta radiol 1961; 55: 81-96
  • 188 O’Neal LW, Ackerman LV. Chondrosarcoma of bone. Cancer 1952; 5: 551-577
  • 189 Coltrera MD, Googe PB, Harrist TJ, Hyams VJ, Schiller AL, Goodman ML. Chondrosarcoma of the temporal bone. Diagnosis and treatment of 13 cases and review of the literature. Cancer 1986; 58: 2689-2696
  • 190 Muckle RP, De la Cruz A, Lo WM. Petrous apex lesions. Am J Otol 1998; 19: 219-225
  • 191 Oghalai JS, Buxbaum JL, Jackler RK, McDermott MW. Skull base chondrosarcoma originating from the petroclival junction. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc [and] Eur Acad. Otol Neurotol 2005; 26: 1052-1060
  • 192 Worley GA, Wareing MJ, Sergeant RJ. Myxoid chondrosarcoma of the external auditory meatus. J Laryngol Otol 1999; 113: 742-743
  • 193 Guild S. A hitherto unrecignized structure, the glomus jugularis, in man. Anat Rec. 1941 79.
  • 194 Spector GJ, Maisel RH, Ogura JH. Glomus tumors in the middle ear. I. An analysis of 46 patients. Laryngoscope 1973; 83: 1652-1672
  • 195 Watzka M. Die Paraganglien. In: Mikr Handbuch Anat Mensch. 4th ed. 1943
  • 196 van Baars FM, Cremers CW, van den Broek P, Veldman JE. Familial glomus tumors: clinical and genetic aspects. Acta Otorhinolaryngol Belg 1981; 35: 50-55
  • 197 Baysal BE. Clinical and molecular progress in hereditary paraganglioma. J Med Genet 2008; 45: 689-694
  • 198 Al-Mefty O, Teixeira A. Complex tumors of the glomus jugulare: criteria, treatment, and outcome. J Neurosurg 2002; 97: 1356-1366
  • 199 Boedeker CC, Hensen EF, Neumann HPH, Maier W, van Nederveen FH, Suárez C. et al. Genetics of hereditary head and neck paragangliomas. Head Neck 2014; 36: 907-916
  • 200 Brown JS. Glomus jugulare tumors revisited: a ten-year statistical follow-up of 231 cases. Laryngoscope 1985; 95: 284-288
  • 201 Fisch U. Microsurgery of the skull base. In: Microsurgery of the skull base.Stuttgart: Thieme; 1988: p 149–153
  • 202 McCabe BF, Fletcher M. Selection of therapy of glomus jugulare tumors. Arch Otolaryngol 1969; 89: 156-159
  • 203 Alford BR, Guilford FR. A comprehensive study of tumors of the glomus jugulare. Laryngoscope 1962; 72: 765-805
  • 204 Megerian CA, McKenna MJ, Nadol JBJ. Non-paraganglioma jugular foramen lesions masquerading as glomus jugulare tumors. Am J Otol 1995; 16: 94-98
  • 205 House WF, Glasscock ME. Glomus tympanicum tumors. Arch Otolaryngol 1968; 87: 550-554
  • 206 Welander J, Söderkvist P, Gimm O. Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas. Endocr Relat Cancer 2011; 18: R253-R276
  • 207 Prades CA, Atassi B, Nazeer H. Metastatic Malignant Paraganglioma: A Case Report and Review of Literature. Vol. 8, World journal of oncology. 2017 p 92-95
  • 208 Brewis C, Bottrill ID, Wharton SB, Moffat DA. Metastases from glomus jugulare tumours. J Laryngol Otol 2000; 114: 17-23
  • 209 Glasscock ME, Harris PF, Newsome G. Glomus tumors: diagnosis and treatment. Laryngoscope 1974; 84: 2006-2032
  • 210 Olsen WL, Dillon WP, Kelly WM, Norman D, Brant-Zawadzki M, Newton TH. MR imaging of paragangliomas. AJR Am J Roentgenol 1987; 148: 201-204
  • 211 Itani M, Mhlanga J, Mariani-Costantini R. Imaging of Pheochromocytoma and Paraganglioma. [Internet]. Paraganglioma: A Multidisciplinary Approach. [Internet]. Brisbane (AU): Codon Publications; 2019. Chapter 3. 2019. Available from: www.ncbi.nlm.nih.gov/books/ NBK543223/. doi: 10.15586/paraganglioma.2019.ch3
  • 212 Taïeb D, Timmers HJ, Hindié E, Guillet BA, Neumann HP, Walz MK. et al. EANM 2012 guidelines for radionuclide imaging of phaeochromocytoma and paraganglioma. Eur J Nucl Med Mol Imaging 2012; 39: 1977-1995
  • 213 Reith W, Kettner M. Diagnosis and treatment of glomus tumors of the skull base and neck. Radiologe 2019; 59: 1051-1057
  • 214 Hafez RFA, Morgan MS, Fahmy OM, Hassan HT. Long-term effectiveness and safety of stereotactic gamma knife surgery as a primary sole treatment in the management of glomus jagulare tumor. Clin Neurol Neurosurg 2018; 168: 34-37
  • 215 Patel NS, Carlson ML, Pollock BE, Driscoll CLW, Neff BA, Foote RL. et al. Long-term tumor control following stereotactic radiosurgery for jugular paraganglioma using 3D volumetric segmentation. J Neurosurg 2018; 1-9
  • 216 Taïeb D, Jha A, Treglia G, Pacak K. Molecular imaging and radionuclide therapy of pheochromocytoma and paraganglioma in the era of genomic characterization of disease subgroups. Endocr Relat Cancer 2019; 26: R627-R652
  • 217 Gloria-Cruz TI, Schachern PA, Paparella MM, Adams GL, Fulton SE. Metastases to temporal bones from primary nonsystemic malignant neoplasms. Arch Otolaryngol Head Neck Surg 2000; 126: 209-214
  • 218 Schuknecht H. Temporal bone removal at autopsy. Preparation and uses. Arch Otolaryngol 1968; 87: 129-137
  • 219 Belal AJ. Metastatic tumours of the temporal bone. A histopathological report. J Laryngol Otol 1985; 99: 839-846
  • 220 Roubaud J-C, Leclere J-C, Mornet E, Marianowski R. Haemangioma of the temporal bone. Eur Ann Otorhinolaryngol Head Neck Dis. 2020
  • 221 Hirai R, Ikeda M, Kishi H, Nomura Y, Shigihara S. A case of middle-ear cavernous lymphangioma with facial palsy. J Laryngol Otol 2011; 125: 405-409
  • 222 Carli J, Andre J. Teratologicaltype dysembryoplastic tumor of the temporomastoid region. Ann Otolaryngol 1958; 75: 791-792
  • 223 Navratil J. Teratome der Paukenhöhle und der Tuba eustachii. Acta Otolaryngol 1965; 60: 360-366
  • 224 Lalwani AKXIV. Skull Base. In: Current Diagnosis & Treatment in Otolaryngology: Head & Neck Surgery. 3rd ed. McGraw-Hill Education; 2011: p 769–844
  • 225 Dazert S, Aletsee C, Brors D, Mlynski R, Sudhoff H, Hildmann H. et al. Rare tumors of the internal auditory canal. Eur Arch oto-rhino-laryngology Off J Eur Fed Oto-Rhino-Laryngological Soc Affil with Ger Soc Oto-Rhino-Laryngology. Head Neck Surg 2005; 262: 550-554
  • 226 Scherl C. Seltene Erkrankungen im Kopf-Hals-Bereich Teil III: Speicheldrüsen und Nervus Facialis (accepted for publication). Laryngorhinootologie. 2021
  • 227 Roosli C, Linthicum FHJ, Cureoglu S, Merchant SN. What is the site of origin of cochleovestibular schwannomas?. Audiol Neurootol 2012; 17: 121-125
  • 228 Rahne T, Plößl S, Plontke SK, Strauss C. Preoperative determination of nerve of origin in patients with vestibular schwannoma. HNO 2018; 66: 16-21
  • 229 Waterval J, Kania R, Somers T. EAONO Position Statement on Vestibular Schwannoma: Imaging Assessment. What are the Indications for Performing a Screening MRI Scan for a Potential Vestibular Schwannoma?. J Int Adv Otol 2018; 14: 95-99
  • 230 Hasso AN, Smith DS. The cerebellopontine angle. Semin Ultrasound CT MR 1989; 10: 280-301
  • 231 Somers T, Kania R, Waterval J, Van Havenbergh T. What is the Required Frequency of MRI Scanning in the Wait and Scan Management?. J Int Adv Otol 2018; 14: 85-89
  • 232 Sakamoto T, Fukuda S, Inuyama Y. Hearing loss and growth rate of acoustic neuromas in follow-up observation policy. Auris Nasus Larynx 2001; 28: S23-S27
  • 233 Paldor I, Chen AS, Kaye AH. Growth rate of vestibular schwannoma. J Clin Neurosci Off J Neurosurg Soc Australas 2016; 32: 1-8
  • 234 Kania R, Vérillaud B, Camous D, Hautefort C, Somers T, Waterval J. et al. EAONO position statement on Vestibular Schwannoma: Imaging Assessment Question: How should growth of Vestibular Schwannoma be defined?. J Int Adv Otol 2018; 14: 90-94
  • 235 Tieleman A, Casselman JW, Somers T, Delanote J, Kuhweide R, Ghekiere J. et al. Imaging of intralabyrinthine schwannomas: a retrospective study of 52 cases with emphasis on lesion growth. AJNR Am J Neuroradiol 2008; 29: 898-905
  • 236 Schulz C, Eßer D, Rosahl S, Baljić I, Kösling S, Plontke SK. Management of vestibular schwannomas. Laryngorhinootologie 2018; 97: 875-896
  • 237 Plontke SK, Rahne T, Pfister M, Götze G, Heider C, Pazaitis N. et al. Intralabyrinthine schwannomas: Surgical management and hearing rehabilitation with cochlear implants. HNO 2017; 65: 136-148
  • 238 Plontke SK, Caye-Thomasen P, Strauss C, Kösling S, Götze G, Siebolts U. et al. Management of transmodiolar and transmacular cochleovestibular schwannomas with and without cochlear implantation. German version. HNO 2020; 68: 734-748
  • 239 Lalwani AK. Meningiomas, epidermoids, and other nonacoustic tumors of the cerebellopontine angle. Otolaryngol Clin North Am 1992; 25: 707-728
  • 240 Lalwani AK, Jackler RK. Preoperative differentiation between meningioma of the cerebellopontine angle and acoustic neuroma using MRI. Otolaryngol neck Surg Off J Am Acad Otolaryngol Neck Surg 1993; 109: 88-95
  • 241 Renowden S. Imaging of the cerebellopontine angle. Pract Neurol 2014; 14: 299-309
  • 242 Roh TH, Park YS, Park YG, Kim SH, Chang JH. Intracranial squamous cell carcinoma arising in a cerebellopontine angle epidermoid cyst: A case report and literature review. Medicine (Baltimore) 2017; 96: e9423
  • 243 Faltaous AA, Leigh EC, Ray P, Wolbert TT. A Rare Transformation of Epidermoid Cyst into Squamous Cell Carcinoma: A Case Report with Literature Review. Am J Case Rep 2019; 20: 1141-1143
  • 244 Turner A, Fraser J. Tuberculosis of the middle-ear cleft in children: A clinical and pathological study. J Laryngol Rhinol Otol 1915; 30: 209-247
  • 245 Ognibene FP. Upper and lower airway manifestations of human immunodeficiency virus infection. Ear Nose Throat J 1990; 69: 424-431
  • 246 Saunders NC, Albert DM. Tuberculous mastoiditis: when is surgery indicated?. Int J Pediatr Otorhinolaryngol 2002; 65: 59-63
  • 247 Jeanes AL, Friedmann I. Tuberculosis of the middle ear. Tubercle. 1960; 41: 109-116
  • 248 Tamari MJ, Itkin P. Penicillin and syphilis of the ear. Eye Ear Nose Throat Mon 1951; 30: 358-366 passim
  • 249 Smith M, Canalis R. Otologic manifestations of AIDS: The otosyphilis connection. Laryngoscope 1989; 99: 365-372
  • 250 Nadol J. Hearing loss of aquired syphilis: Diagnosis confirmed by incudectomy. Laryngoscope 1975; 85: 1888-1897
  • 251 Peled C, El-Seid S, Bahat-Dinur A, Tzvi-Ran LR, Kraus M, Kaplan D. Necrotizing Otitis Externa-Analysis of 83 Cases: Clinical Findings and Course of Disease. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc [and] Eur Acad. Otol Neurotol 2019; 40: 56-62
  • 252 Abu Eta R, Gavriel H, Stephen K, Eviatar E, Yeheskeli E. The significance of tissue biopsy for fungi in necrotizing otitis externa. Eur Arch oto-rhino-laryngology Off J Eur Fed Oto-Rhino-Laryngological Soc Affil with Ger Soc Oto-Rhino-Laryngology – Head Neck Surg 2018; 275: 2941-2945
  • 253 Chandler JR. Malignant external otitis and facial paralysis. Otolaryngol Clin North Am 1974; 7: 375-383
  • 254 Chandler JR. Malignant external otitis. Laryngoscope 1968; 78: 1257-1294
  • 255 Chandler JR. Malignant external otitis: further considerations. Ann Otol Rhinol Laryngol 1977; 86: 417-428
  • 256 Nadol JBJ. Histopathology of Pseudomonas osteomyelitis of the temporal bone starting as malignant external otitis. Am J Otolaryngol 1980; 1: 359-371
  • 257 Kohut RI, Lindsay JR. Necrotizing (“malignant”) external otitis histopathologic processes. Ann Otol Rhinol Laryngol 1979; 88: 714-720
  • 258 Mahdyoun P, Pulcini C, Gahide I, Raffaelli C, Savoldelli C, Castillo L. et al. Necrotizing otitis externa: a systematic review. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc [and] Eur Acad. Otol Neurotol 2013; 34: 620-629
  • 259 Amaro CE, Espiney R, Radu L, Guerreiro F. Malignant (necrotizing) externa otitis: the experience of a single hyperbaric centre. Eur Arch oto-rhino-laryngology Off J Eur Fed Oto-Rhino-Laryngological Soc Affil with Ger Soc Oto-Rhino-Laryngology – Head Neck Surg 2019; 276: 1881-1887
  • 260 Harris JB, LaRocque RC, Qadri F, Ryan ET, Calderwood SB. Cholera. Lancet (London, England) 2012; 379: 2466-2476
  • 261 Pang B, Yan M, Cui Z, Ye X, Diao B, Ren Y et al. Genetic diversity of toxigenic and nontoxigenic Vibrio cholerae serogroups O1 and O139 revealed by array-based comparative genomic hybridization. J Bacteriol 2007; 189: 4837–4849
  • 262 Zhang X, Lu Y, Qian H, Liu G, Mei Y, Jin F. et al. Non-O1, Non-O139 Vibrio cholerae (NOVC) Bacteremia: Case Report and Literature Review, 2015–2019. Vol. 13, Infection and drug resistance. New Zealand p. 1009-1016
  • 263 Kechker P, Senderovich Y, Ken-Dror S, Laviad-Shitrit S, Arakawa E, Halpern M. Otitis Media Caused by V. cholerae O100: A Case Report and Review of the Literature. Front Microbiol 2017; 8: 1619
  • 264 Madeira JT, Summers GW. Epidural mastoid pneumatocele. Radiology 1977; 122: 727-728
  • 265 Krisht KM, Eli IM, Palmer CA, Schmidt RH. Giant Spontaneous Epidural Pneumatocele: Case Report and Review of the Literature. World Neurosurg 2015; 84: 2075. e7-12
  • 266 Schilde S, Plontke S, Seiwerth I, Kösling S. Abnormal mastoid pneumatization. HNO 2019; 67: 876-880
  • 267 Graf K. Spontaneous giant pneumatocele of the mastoid. Pract Otorhinolaryngol (Basel) 1955; 17: 462-466
  • 268 Keshet N, Abu-Tair J, Zaharia B, Abdalla-Aslan R, Aframian DJ, Zadik Y. Superficial oral mucoceles in cancer patient after radiation therapy: An overlooked yet imperative phenomenon. Vol. 52 Oral oncology. England 2016; e1-e2
  • 269 Mnejja M, Hammami B, Achour I, Chakroun A, Charfeddine I, Frikha M. et al. Post-radiation mucocele in two patients treated for nasopharyngeal cancer. Cancer Radiother 2011; 15: 254-256
  • 270 Mark IHW, Tan HKK. Sphenoid mucocele after radiation for the treatment of nasopharyngeal carcinoma. J Otolaryngol – head neck Surg = Le J d’oto-rhino-laryngologie Chir cervico-faciale 2008; 37: E28-E31
  • 271 Tonni D, Sessa M, Redaelli de Zinis LO. Primary mucocele of the mastoid: An incidental finding. Vol. 8, Clinical case reports. England. 2020 p 461-465
  • 272 Karandikar A, Goh J, Loke SC, Yeo SB, Tan TY. Mucous retention cyst of temporal bone: a mimic of cholesteatoma on DW-MRI. Am J Otolaryngol 2013; 34: 753-754
  • 273 Ata N, Erkilic S. Mucous retention cyst of mastoid bone mimicking cholesteatoma. Ear Nose Throat J 2017; 96: E41-E42
  • 274 Waltner JC, Karatay S. Cysts of the mastoid bone. Arch Otolaryngol 1947; 46: 398-404
  • 275 Richardson GS. A cyst of the mastoid; report of a case. Ann Otol Rhinol Laryngol 1956; 65: 214-217
  • 276 Nomura Y, Takemoto K, Komatsuzaki A. The mastoid cyst. Report of a case. Laryngoscope 1971; 81: 438-446
  • 277 Zimmerman BE, Proud GO. Primary cysts of the mastoid process. Laryngoscope 1983; 93: 805-807
  • 278 Kavanagh KT, Giltman LI, Babin RW. Erosive mucosal cysts of the temporal bone. A case report with review of the pathogenesis. Am J Otol 1986; 7: 270-274
  • 279 Tan CY, Chong S. Shaw C-KL. Primary mastoid cyst. J Laryngol Otol 2013; 127: S48-S50
  • 280 Hwang PH, Jackler RK. Facial nerve dysfunction associated with cystic lesions of the mastoid. Otolaryngol Head Neck Surg 1998; 119: 668-672
  • 281 Mohammed ER, Profant M. Spontaneous otogenic pneumocephalus. Acta Otolaryngol 2011; 131: 670-674
  • 282 Andrews JC, Canalis RF. Otogenic pneumocephalus. Laryngoscope. 1986; 96: 521-528
  • 283 Sanna M, Fois P, Russo A, Falcioni M. Management of meningoencephalic herniation of the temporal bone: Personal experience and literature review. Laryngoscope 2009; 119: 1579-1585
  • 284 Kenning TJ, Willcox TO, Artz GJ, Schiffmacher P, Farrell CJ, Evans JJ. Surgical management of temporal meningoencephaloceles, cerebrospinal fluid leaks, and intracranial hypertension: treatment paradigm and outcomes. Neurosurg Focus 2012; 32: E6
  • 285 Kutz JWJ, Tolisano AM. Diagnosis and management of spontaneous cerebrospinal fluid fistula and encephaloceles. Curr Opin Otolaryngol Head Neck Surg 2019; 27: 369-375
  • 286 Nelson RF, Roche JP, Gantz BJ, Hansen MR. Middle Cranial Fossa (MCF) Approach Without the Use of Lumbar Drain for the Management of Spontaneous Cerebral Spinal Fluid (CSF) Leaks. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc [and] Eur Acad. Otol Neurotol 2016; 37: 1625-1629
  • 287 Hernandez-Montero E, Caballero E, García-Ibanez L. Surgical management of middle cranial fossa bone defects: meningoencephalic herniation and cerebrospinal fluid leaks. Am J Otolaryngol 2020; 41: 102560
  • 288 BLACK BK, SMITH DE. Nasal glioma; 2 cases with recurrence. AMA Arch Neurol Psychiatry 1950; 64: 614-630
  • 289 Ofodile FA, Aghadiuno PU, Oyemade O, Adebonojo T. Heterotopic brain in the tongue. Plast Reconstr Surg 1982; 69: 120-124
  • 290 Scheiner AJ, Frayer WC, Rorke LB, Heher K. Ectopic brain tissue in the orbit. Eye (Lond) 1999; 13: 251-254
  • 291 Uğuz MZ, Arslanoğlu S, Terzi S, Etit D. Glial heterotopia of the middle ear. J Laryngol Otol 2007; 121: e4
  • 292 McGregor DH, Cherian R, Kepes JJ, Kepes M. Case reports: heterotopic brain tissue of middle ear associated with cholesteatoma. Am J Med Sci 1994; 308: 180-183
  • 293 Lee JI, Kim KK, Park YK, Eah KY, Kim JR. Glial choristoma in the middle ear and mastoid bone: a case report. J Korean Med Sci 2004; 19: 155-158
  • 294 Plontke SK, Preyer S, Pressler H, Mundinger PM, Plinkert PK. Glial lesion of the infratemporal fossa presenting as a soft tissue middle ear mass — rudimentary encephalocele or neural crest remnant? 2000; 56: 141-147
  • 295 Abrahams JJ, Eklund JA. Diagnostic radiology of the cranial base. Clin Plast Surg 1995; 22: 373-405
  • 296 Koch BL, Ball WSJ. Congenital malformations causing skull base changes. Neuroimaging Clin N Am 1994; 4: 479-498
  • 297 Lalwani AK, Jackler RK. Spontaneous hemotympanum associated with chronic middle ear effusion. Am J Otol 1991; 12: 455-458
  • 298 Maeta M, Saito R, Nakagawa F, Miyahara T. Surgical intervention in middle-ear cholesterol granuloma. J Laryngol Otol 2003; 117: 344-348
  • 299 Paparella MM, Lim DJ. Pathogenesis and pathology of the “idiopathic” blue ear drum. Arch Otolaryngol 1967; 85: 249-258
  • 300 Plontke S, Koitschev A, Ernemann U, Pressler H, Zimmermann R, Plasswilm L. Massive Gorham-Stout osteolysis of the temporal bone and the craniocervical transition. HNO 2002; 50: 354-357
  • 301 Gorham LW, Stout AP. Massive osteolysis (acute spontaneous absorption of bone, phantom bone, disappearing bone); its relation to hemangiomatosis. J Bone Joint Surg Am 1955; 37-A 5: 985-1004
  • 302 Patel DV. Gorham’s disease or massive osteolysis. Clin Med Res 2005; 3: 65-74
  • 303 Simon F, Luscan R, Khonsari RH, Toubiana J, Belhous K, James S. et al. Management of Gorham Stout disease with skull-base defects: Case series of six children and literature review. Int J Pediatr Otorhinolaryngol 2019; 124: 152-156
  • 304 Pace A, Iannella G, Riminucci M, Corsi A, Magliulo G. Tympano-Mastoid Cholesterol Granuloma: Case Report and Review of the Literature. Clin Med Insights Case Rep 2020; 13: 1179547620958728
  • 305 Gore MR, Zanation AM, Ebert CS, Senior BA. Cholesterol granuloma of the petrous apex. Otolaryngol Clin North Am 2011; 44: 1043-1058
  • 306 Olcott C, Strasnick B. A blue middle ear mass: Cholesterol granuloma mimicking a glomus tumor and endolymphatic sac tumor. Am J Otolaryngol 2017; 38: 100-102
  • 307 Kohanski MA, Palmer JN, Adappa ND. Indications and endonasal treatment of petrous apex cholesterol granulomas. Curr Opin Otolaryngol Head Neck Surg 2019; 27: 54-58
  • 308 Sanna M, Dispenza F, Mathur N, De Stefano A, De Donato G. Otoneurological management of petrous apex cholesterol granuloma. Am J Otolaryngol 2009; 30: 407-414
  • 309 Raghavan D, Lee TC, Curtin HD. Cholesterol Granuloma of the Petrous Apex: A 5-Year Review of Radiology Reports with Follow-Up of Progression and Treatment. J Neurol Surg B Skull Base 2015; 76: 266-271
  • 310 Boedeker CC, Kayser G, Ridder GJ, Maier W, Schipper J. Giant-cell reparative granuloma of the temporal bone: a case report and review of the literature. Ear Nose Throat J 2003; 82: 926-929 933-934, 936-937
  • 311 Jaffe HL. Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-oseous) dysplasia of the jawbones. Oral Surg Oral Med Oral Pathol 1953; 6: 159-175
  • 312 Dietz A, Duprez T, Lelotte J, Finet P, Wilms G. Letter to the editor: giant cell reparative granuloma of the temporal bone. Acta neurologica Belgica; Italy: 2020
  • 313 Bernard F, Troude L, Bouvier C, Roche P-H. “Giant cell reparative tumor: An exceptional differential diagnosis for a lytic lesion of the temporal bone”. Neurochirurgie 2016; 62: 332-335
  • 314 Menge M, Maier W, Feuerhake F, Kaminsky J, Pfeiffer J. Giant cell reparative granuloma of the temporal bone. Acta Neurochir (Wien) 2009; 151: 397-399
  • 315 Ciappetta P, Salvati M, Bernardi C, Raco A, Di Lorenzo N. Giant cell reparative granuloma of the skull base mimicking an intracranial tumor. Case report and review of the literature. Surg Neurol 1990; 33: 52-56
  • 316 Plontke SK-R, Adler C-P, Gawlowski J, Ernemann U, Friese SA, Plinkert PK. Recurrent giant cell reparative granuloma of the skull base and the paranasal sinuses presenting with acute one-sided blindness. Vol. 12, Skull base: official journal of North American Skull Base Society ... [et al.]. 2002 p 9-17
  • 317 Auclair PL, Cuenin P, Kratochvil FJ, Slater LJ, Ellis GL. A clinical and histomorphologic comparison of the central giant cell granuloma and the giant cell tumor. Oral Surg Oral Med Oral Pathol 1988; 66: 197-208
  • 318 Cho Y-S, Lee H-S, Kim S-W, Chung K-H, Lee D-K, Koh W-J. et al. Tuberculous otitis media: a clinical and radiologic analysis of 52 patients. Laryngoscope 2006; 116: 921-927
  • 319 Plontke SK, Kösling S, Schilde S, Wittlinger J, Kisser U. The infracochlear approach for diagnostic petrous apicotomy. HNO 2019; 67: 791-795
  • 320 Kleijwegt M, Ho V, Visser O, Godefroy W, van der Mey A. Real Incidence of Vestibular Schwannoma? Estimations From a National Registry. Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc [and] Eur Acad. Otol Neurotol 2016; 37: 1411-1417
  • 321 Quigley C, Deady S, Hughes E, McElnea E, Zgaga L, Chetty S. National incidence of eyelid cancer in Ireland (2005–2015). Eye (Lond) 2019; 33: 1534-1539
  • 322 Berner K, Zaikova O, Johannesen TB, Hall KS, Bruland ØS. Validity and completeness of the Scandinavian Sarcoma Group Central Register by comparison with a nationwide cohort of patients with osteosarcoma in Norway. Vol. 118, Journal of surgical oncology. United States. 2018: 246-247
  • 323 Heller J, Kraus F, Scheich M, Mlynski R. Therapie der traumatischen Stapesverletzung. In: 80th Annual Meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery. 2009