Download PDF
Endoscopy 2021; 53(05): 522-534
DOI: 10.1055/a-1442-2395
Guideline

Endoscopic management of superficial nonampullary duodenal tumors: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Geoffroy Vanbiervliet
 1   Department of Digestive Endoscopy, Centre Hospitalier Universitaire de Nice, Nice, France
,
Alan Moss
 2   Department of Endoscopic Services, Western Health, Melbourne, Australia
 3   Department of Medicine - Western Health, Melbourne Medical School, The University of Melbourne, Victoria, Australia
,
Marianna Arvanitakis
 4   Gastroenterology, Hepatopancreatology, and Digestive Oncology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium
,
Urban Arnelo
 5   Department of Surgery, Centre for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden
,
Torsten Beyna 
 6   Department of Gastroenterology, Evangelisches Krankenhaus Düsseldorf, Düsseldorf, Nordrhein-Westfalen, Germany
,
Olivier Busch
 7   Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
,
Pierre H. Deprez 
 8   Gastroenterology and Hepatology Department, Cliniques universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
,
Lumir Kunovsky 
 9   Department of Gastroenterology and Internal Medicine, University Hospital Brno, Faculty of Medicine, Masaryk University, Brno, Czech Republic
10   Department of Surgery, University Hospital Brno, Faculty of Medicine, Masaryk University, Brno, Czech Republic
,
Alberto Larghi
11   Digestive Endoscopy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
,
Gianpiero Manes 
12   Aziende Socio Sanitaria Territoriale Rhodense, Gastroenterology, Garbagnate Milanese, Italy
,
Bertrand Napoleon
13   Service de Gastroentérologie, Hôpital Privé Jean Mermoz, Ramsay Générale de Santé, Lyon, France
,
Kumanan Nalankilli
 2   Department of Endoscopic Services, Western Health, Melbourne, Australia
 3   Department of Medicine - Western Health, Melbourne Medical School, The University of Melbourne, Victoria, Australia
,
Manu Nayar
14   Department of Gastroenterology, Freeman Hospital, Newcastle upon Tyne, UK
,
Enrique Pérez-Cuadrado-Robles 
15   Department of Gastroenterology, Georges-Pompidou European Hospital, AP-HP Centre - Université de Paris, Paris, France
,
Stefan Seewald
16   Center of Gastroenterology Centre, Klinik Hirslanden, Zurich, Switzerland
,
Marin Strijker
17   Department of Gastroenterology, Hôpital Nord, Assistance publique des hôpitaux de Marseille, Marseille, France
,
Marc Barthet 
17   Department of Gastroenterology, Hôpital Nord, Assistance publique des hôpitaux de Marseille, Marseille, France
,
Jeanin E. van Hooft
18   Department of Gastroenterology and Hepatology, Leiden University Medical Center, The Netherlands
› Author Affiliations
› Further Information
Also available at
   Permissions and Reprints

Main recommendations

1 ESGE recommends that all duodenal adenomas should be considered for endoscopic resection as progression to invasive carcinoma is highly likely.
Strong recommendation, low quality evidence.

2 ESGE recommends performance of a colonoscopy, if that has not yet been done, in cases of duodenal adenoma.

Strong recommendation, low quality evidence.

3 ESGE recommends the use of the cap-assisted method when the location of the minor and/or major papilla and their relationship to a duodenal adenoma is not clearly established during forward-viewing endoscopy.

Strong recommendation, moderate quality evidence.

4 ESGE recommends the routine use of a side-viewing endoscope when a laterally spreading adenoma with extension to the minor and/or major papilla is suspected.

Strong recommendation, low quality evidence.

5 ESGE suggests cold snare polypectomy for small (< 6 mm in size) nonmalignant duodenal adenomas.

Weak recommendation, low quality evidence.

6 ESGE recommends endoscopic mucosal resection (EMR) as the first-line endoscopic resection technique for nonmalignant large nonampullary duodenal adenomas.
Strong recommendation, moderate quality evidence.

7 ESGE recommends that endoscopic submucosal dissection (ESD) for duodenal adenomas is an effective resection technique only in expert hands.

Strong recommendation, low quality evidence.

8 ESGE recommends using techniques that minimize adverse events such as immediate or delayed bleeding or perforation. These may include piecemeal resection, defect closure techniques, noncontact hemostasis, and other emerging techniques, and these should be considered on a case-by-case basis.

Strong recommendation, low quality evidence.

9 ESGE recommends endoscopic surveillance 3 months after the index treatment. In cases of no recurrence, a further follow-up endoscopy should be done 1 year later. Thereafter, surveillance intervals should be adapted to the lesion site, en bloc resection status, and initial histological result.

Strong recommendation, low quality evidence.

Appendix 1s



Publication History

Article published online:
01 April 2021

© 2021. European Society of Gastrointestinal Endoscopy. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • References

  • 1 Goda K, Kikuchi D, Yamamoto Y. et al. Endoscopic diagnosis of superficial non-ampullary duodenal epithelial tumors in Japan: Multicenter case series. Dig Endosc 2014; 26 (Suppl. 02) 23-29
    CrossrefPubMedGoogle Scholar
  • 2 van Leerdam ME, Roos VH, van Hooft JE. et al. Endoscopic management of polyposis syndromes: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2019; 51: 877-895
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 Jung SH, Chung WC, Kim EJ. et al. Evaluation of non-ampullary duodenal polyps: comparison of non-neoplastic and neoplastic lesions. World J Gastroenterol 2010; 16: 5474-5480
    CrossrefPubMedGoogle Scholar
  • 4 Höchter W, Weingart J, Seib HJ. et al. [Duodenal polyps. Incidence, histologic substrate and significance] [Article in German]. Dtsch Med Wochenschr 1984; 109: 1183-1186
    PubMedGoogle Scholar
  • 5 Jepsen JM, Persson M, Jakobsen NO. et al. Prospective study of prevalence and endoscopic and histopathologic characteristics of duodenal polyps in patients submitted to upper endoscopy. Scand J Gastroenterol 1994; 29: 483-487
    CrossrefPubMedGoogle Scholar
  • 6 Alkhatib AA. Sporadic nonampullary tubular adenoma of the duodenum: Prevalence and patients’ characteristics. Turk J Gastroenterol 2019; 30: 112-113
    PubMedGoogle Scholar
  • 7 Johnson MD, Mackey R, Brown N. et al. Outcome based on management for duodenal adenomas: sporadic versus familial disease. J Gastrointest Surg 2010; 14: 229-235
    CrossrefPubMedGoogle Scholar
  • 8 Syngal S, Brand RE, Church JM. et al. ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol 2015; 110: 223-262; quiz 263
    CrossrefPubMedGoogle Scholar
  • 9 Matsuzaki J, Suzuki H, Shimoda M. et al. Clinical and endoscopic findings to assist the early detection of duodenal adenoma and adenocarcinoma. United Eur Gastroenterol J 2019; 7: 250-260
    CrossrefPubMedGoogle Scholar
  • 10 Bisschops R, Areia M, Coron E. et al. Performance measures for upper gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative. Endoscopy 2016; 48: 843-864
    Article in Thieme ConnectPubMedGoogle Scholar
  • 11 Wu Z-J, Lin Y, Xiao J. et al. Clinical significance of colonoscopy in patients with upper gastrointestinal polyps and neoplasms: a meta-analysis. PloS One 2014; 9: e91810
    CrossrefPubMedGoogle Scholar
  • 12 Genta RM, Hurrell JM, Sonnenberg A. Duodenal adenomas coincide with colorectal neoplasia. Dig Dis Sci 2014; 59: 2249-2254
    CrossrefPubMedGoogle Scholar
  • 13 Okada K, Fujisaki J, Kasuga A. et al. Sporadic nonampullary duodenal adenoma in the natural history of duodenal cancer: a study of follow-up surveillance. Am J Gastroenterol 2011; 106: 357-364
    CrossrefPubMedGoogle Scholar
  • 14 Niwa A, Kuwano S, Tomita H. et al. The different pathogeneses of sporadic adenoma and adenocarcinoma in non-ampullary lesions of the proximal and distal duodenum. Oncotarget 2017; 8: 41078-41090
    CrossrefPubMedGoogle Scholar
  • 15 Toya Y, Endo M, Akasaka R. et al. Clinicopathological features and magnifying chromoendoscopic findings of non-ampullary duodenal epithelial tumors. Digestion 2018; 97: 219-227
    CrossrefPubMedGoogle Scholar
  • 16 Tsuji S, Doyama H, Tsuji K. et al. Preoperative endoscopic diagnosis of superficial non-ampullary duodenal epithelial tumors, including magnifying endoscopy. World J Gastroenterol 2015; 21: 11832-11841
    CrossrefPubMedGoogle Scholar
  • 17 Kuroki K, Sanomura Y, Oka S. et al. Clinical outcomes of endoscopic resection for superficial non-ampullary duodenal tumors. Endosc Int Open 2020; 8: E354-E359
    Article in Thieme ConnectPubMedGoogle Scholar
  • 18 Pérez-Cuadrado-Robles E, Quénéhervé L, Margos W. et al. ESD versus EMR in non-ampullary superficial duodenal tumors: a systematic review and meta-analysis. Endosc Int Open 2018; 6: E998-E1007
    Article in Thieme ConnectPubMedGoogle Scholar
  • 19 Klein A, Nayyar D, Bahin FF. et al. Endoscopic mucosal resection of large and giant lateral spreading lesions of the duodenum: success, adverse events, and long-term outcomes. Gastrointest Endosc 2016; 84: 688-696
    CrossrefPubMedGoogle Scholar
  • 20 Pérez-Cuadrado-Robles E, Quénéhervé L, Margos W. et al. Comparative analysis of ESD versus EMR in a large European series of non-ampullary superficial duodenal tumors. Endosc Int Open 2018; 6: E1008-E1014
    Article in Thieme ConnectPubMedGoogle Scholar
  • 21 Lopez-Ceron M, van den Broek FJC, Mathus-Vliegen EM. et al. The role of high-resolution endoscopy and narrow-band imaging in the evaluation of upper GI neoplasia in familial adenomatous polyposis. Gastrointest Endosc 2013; 77: 542-550
    CrossrefPubMedGoogle Scholar
  • 22 Yap CK, Ng HS. Cap-fitted gastroscopy improves visualization and targeting of lesions. Gastrointest Endosc 2001; 53: 93-95
    CrossrefPubMedGoogle Scholar
  • 23 Choi YR, Han J-H, Cho YS. et al. Efficacy of cap-assisted endoscopy for routine examining the ampulla of Vater. World J Gastroenterol 2013; 19: 2037-2043
    CrossrefPubMedGoogle Scholar
  • 24 Kallenberg FGJ, Bastiaansen BAJ, Dekker E. Cap-assisted forward-viewing endoscopy to visualize the ampulla of Vater and the duodenum in patients with familial adenomatous polyposis. Endoscopy 2017; 49: 181-185
    Article in Thieme ConnectPubMedGoogle Scholar
  • 25 Abdelhafez M, Phillip V, Hapfelmeier A. et al. Cap assisted upper endoscopy for examination of the major duodenal papilla: a randomized, blinded, controlled crossover study (CAPPA Study). Am J Gastroenterol 2017; 112: 725-733
    CrossrefPubMedGoogle Scholar
  • 26 Abdelhafez M, Phillip V, Hapfelmeier A. et al. Comparison of cap-assisted endoscopy vs. side-viewing endoscopy for examination of the major duodenal papilla: a randomized, controlled, non-inferiority crossover study. . Endoscopy 2019; 51: 419-426
    Article in Thieme ConnectPubMedGoogle Scholar
  • 27 Shi X, Luo H, Ning B. et al. Effect of cap-assisted esophagogastroduodenoscopy on examination of the major duodenal papilla: a non-inferior, randomized controlled trial. Endoscopy 2019; 51: 427-435
    Article in Thieme ConnectPubMedGoogle Scholar
  • 28 Kiesslich R, Mergener K, Naumann C. et al. Value of chromoendoscopy and magnification endoscopy in the evaluation of duodenal abnormalities: a prospective, randomized comparison. Endoscopy 2003; 35: 559-563
    Article in Thieme ConnectPubMedGoogle Scholar
  • 29 Picasso M, Filiberti R, Blanchi S. et al. The role of chromoendoscopy in the surveillance of the duodenum of patients with familial adenomatous polyposis. Dig Dis Sci 2007; 52: 1906-1909
    CrossrefPubMedGoogle Scholar
  • 30 Dekker E, Boparai KS, Poley JW. et al. High resolution endoscopy and the additional value of chromoendoscopy in the evaluation of duodenal adenomatosis in patients with familial adenomatous polyposis. Endoscopy 2009; 41: 666-669
    Article in Thieme ConnectPubMedGoogle Scholar
  • 31 Hurley JJ, Thomas LE, Walton S-J. et al. The impact of chromoendoscopy for surveillance of the duodenum in patients with MUTYH-associated polyposis and familial adenomatous polyposis. Gastrointest Endosc 2018; 88: 665-673
    CrossrefPubMedGoogle Scholar
  • 32 Shahid MW, Buchner A, Gomez V. et al. Diagnostic accuracy of probe-based confocal laser endomicroscopy and narrow band imaging in detection of dysplasia in duodenal polyps. J Clin Gastroenterol 2012; 46: 382-389
    CrossrefPubMedGoogle Scholar
  • 33 Yamasaki Y, Takeuchi Y, Kanesaka T. et al. Differentiation between duodenal neoplasms and non-neoplasms using magnifying narrow-band imaging – Do we still need biopsies for duodenal lesions?. Dig Endosc 2020; 32: 84-95
    CrossrefPubMedGoogle Scholar
  • 34 Yoshimura N, Goda K, Tajiri H. et al. Endoscopic features of nonampullary duodenal tumors with narrow-band imaging. Hepatogastroenterology 2010; 57: 462-467
    PubMedGoogle Scholar
  • 35 Kikuchi D, Hoteya S, Iizuka T. et al. Diagnostic algorithm of magnifying endoscopy with narrow band imaging for superficial non-ampullary duodenal epithelial tumors. Dig Endosc 2014; 26 (Suppl. 02) 16-22
    CrossrefPubMedGoogle Scholar
  • 36 Kakushima N, Yoshida M, Yamaguchi Y. et al. Magnified endoscopy with narrow-band imaging for the differential diagnosis of superficial non-ampullary duodenal epithelial tumors. Scand J Gastroenterol 2019; 54: 128-134
    CrossrefPubMedGoogle Scholar
  • 37 Toya Y, Endo M, Oizumi T. et al. Diagnostic algorithm of magnifying endoscopy with crystal violet staining for non-ampullary duodenal epithelial tumors. Dig Endosc 2020; 32: 1066-1073
    CrossrefPubMedGoogle Scholar
  • 38 Mizumoto T, Sanomura Y, Tanaka S. et al. Clinical usefulness of magnifying endoscopy for non-ampullary duodenal tumors. Endosc Int Open 2017; 5: E297-E302
    Article in Thieme ConnectPubMedGoogle Scholar
  • 39 Kakushima N, Kanemoto H, Sasaki K. et al. Endoscopic and biopsy diagnoses of superficial, nonampullary, duodenal adenocarcinomas. World J Gastroenterol 2015; 21: 5560-5567
    CrossrefPubMedGoogle Scholar
  • 40 Kinoshita S, Nishizawa T, Ochiai Y. et al. Accuracy of biopsy for the preoperative diagnosis of superficial nonampullary duodenal adenocarcinoma. Gastrointest Endosc 2017; 86: 329-332
    CrossrefPubMedGoogle Scholar
  • 41 Ma MX, Bourke MJ. Management of duodenal polyps. Best Pract Res Clin Gastroenterol 2017; 31: 389-399
    CrossrefPubMedGoogle Scholar
  • 42 Chen W-C, Wallace MB. Endoscopic management of mucosal lesions in the gastrointestinal tract. Expert Rev Gastroenterol Hepatol 2016; 10: 481-495
    CrossrefPubMedGoogle Scholar
  • 43 Ferlitsch M, Moss A, Hassan C. et al. Colorectal polypectomy and endoscopic mucosal resection (EMR): European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy 2017; 49: 270-297
    Article in Thieme ConnectPubMedGoogle Scholar
  • 44 Hamada K, Takeuchi Y, Ishikawa H. et al. Feasibility of cold snare polypectomy for multiple duodenal adenomas in patients with familial adenomatous polyposis: a pilot study. Dig Dis Sci 2016; 61: 2755-2759
    CrossrefPubMedGoogle Scholar
  • 45 Patel NJ, Ponugoti PL, Rex DK. Cold snare polypectomy effectively reduces polyp burden in familial adenomatous polyposis. Endosc Int Open 2016; 4: E472-474
    Article in Thieme ConnectPubMedGoogle Scholar
  • 46 Hamada K, Takeuchi Y, Ishikawa H. et al. Safety of cold snare polypectomy for duodenal adenomas in familial adenomatous polyposis: a prospective exploratory study. Endoscopy 2018; 50: 511-517
    Article in Thieme ConnectPubMedGoogle Scholar
  • 47 Maruoka D, Matsumura T, Kasamatsu S. et al. Cold polypectomy for duodenal adenomas: a prospective clinical trial. Endoscopy 2017; 49: 776-783
    Article in Thieme ConnectPubMedGoogle Scholar
  • 48 Probst A, Freund S, Neuhaus L. et al. Complication risk despite preventive endoscopic measures in patients undergoing endoscopic mucosal resection of large duodenal adenomas. Endoscopy 2020; 52: 847-855
    Article in Thieme ConnectPubMedGoogle Scholar
  • 49 Fanning SB, Bourke MJ, Williams SJ. et al. Giant laterally spreading tumors of the duodenum: endoscopic resection outcomes, limitations, and caveats. Gastrointest Endosc 2012; 75: 805-812
    CrossrefPubMedGoogle Scholar
  • 50 Lépilliez V, Chemaly M, Ponchon T. et al. Endoscopic resection of sporadic duodenal adenomas: an efficient technique with a substantial risk of delayed bleeding. Endoscopy 2008; 40: 806-810
    Article in Thieme ConnectPubMedGoogle Scholar
  • 51 Bourke MJ. Endoscopic resection in the duodenum: current limitations and future directions. Endoscopy 2013; 45: 127-132
    Article in Thieme ConnectPubMedGoogle Scholar
  • 52 Navaneethan U, Hasan MK, Lourdusamy V. et al. Efficacy and safety of endoscopic mucosal resection of non-ampullary duodenal polyps: a systematic review. Endosc Int Open 2016; 4: E699-708
    Article in Thieme ConnectPubMedGoogle Scholar
  • 53 Jamil LH, Kashani A, Peter N. et al. Safety and efficacy of cap-assisted EMR for sporadic nonampullary duodenal adenomas. Gastrointest Endosc 2017; 86: 666-672
    CrossrefPubMedGoogle Scholar
  • 54 Valerii G, Tringali A, Landi R. et al. Endoscopic mucosal resection of non-ampullary sporadic duodenal adenomas: a retrospective analysis with long-term follow-up. Scand J Gastroenterol 2018; 53: 490-494
    CrossrefPubMedGoogle Scholar
  • 55 Tomizawa Y, Ginsberg GG. Clinical outcome of EMR of sporadic, non-ampullary, duodenal adenomas: a 10-year retrospective. Gastrointest Endosc 2018; 87: 1270-1278
    CrossrefPubMedGoogle Scholar
  • 56 Valli PV, Mertens JC, Sonnenberg A. et al. Nonampullary duodenal adenomas rarely recur after complete endoscopic resection: a Swiss experience including a literature review. Digestion 2017; 96: 149-157
    CrossrefPubMedGoogle Scholar
  • 57 Singh A, Siddiqui UD, Konda VJ. et al. Safety and efficacy of EMR for sporadic, nonampullary duodenal adenomas: a single U.S. center experience (with video). Gastrointest Endosc 2016; 84: 700-8
    CrossrefPubMedGoogle Scholar
  • 58 Zou J, Chai N, Linghu E. et al. Clinical outcomes of endoscopic resection for non-ampullary duodenal laterally spreading tumors. Surg Endosc 2019; 33: 4048-4056
    CrossrefPubMedGoogle Scholar
  • 59 Kiguchi Y, Kato M, Nakayama A. et al. Feasibility study comparing underwater endoscopic mucosal resection and conventional endoscopic mucosal resection for superficial non-ampullary duodenal epithelial tumor < 20 mm. Dig Endosc 2020; 32: 753-760
    CrossrefPubMedGoogle Scholar
  • 60 Cosgrove N, Siddiqui AA, Kistler CA. et al. Endoscopic mucosal resection of large non-ampullary duodenal polyps: technical aspects and long-term therapeutic outcomes. Minerva Gastroenterol Dietol 2016; 62: 131-137
    PubMedGoogle Scholar
  • 61 Na HK, Kim DH, Ahn JY. et al. Clinical outcomes following endoscopic treatment for sporadic nonampullary duodenal adenoma. Dig Dis 2020; 38: 364-372
    CrossrefPubMedGoogle Scholar
  • 62 Cassani LS, Lanke G, Chen H-C. et al. Comparison of nonampullary duodenal adenomas in patients with familial adenomatous polyposis versus patients with sporadic adenomas. Gastrointest Endosc 2017; 85: 803-812
    CrossrefPubMedGoogle Scholar
  • 63 Klein A, Ahlenstiel G, Tate DJ. et al. Endoscopic resection of large duodenal and papillary lateral spreading lesions is clinically and economically advantageous compared with surgery. Endoscopy 2017; 49: 659-667
    Article in Thieme ConnectPubMedGoogle Scholar
  • 64 Yamasaki Y, Uedo N, Takeuchi Y. et al. Underwater endoscopic mucosal resection for superficial nonampullary duodenal adenomas. Endoscopy 2018; 50: 154-158
    PubMedGoogle Scholar
  • 65 Shibukawa G, Irisawa A, Sato A. et al. Endoscopic mucosal resection performed underwater for nonampullary duodenal epithelial tumor: evaluation of feasibility and safety. Gastroenterol Res Pract 2018; DOI: 10.1155/2018/7490961.
    CrossrefPubMedGoogle Scholar
  • 66 Javia SB, Chathadi K. Cold snare piecemeal endoscopic mucosal resection of a very large duodenal adenoma. Endoscopy 2019; 51: E217-E218
    Article in Thieme ConnectPubMedGoogle Scholar
  • 67 Choksi N, Elmunzer BJ, Stidham RW. et al. Cold snare piecemeal resection of colonic and duodenal polyps ≥1 cm. Endosc Int Open 2015; 3: E508-E513
    Article in Thieme ConnectPubMedGoogle Scholar
  • 68 Ochiai Y, Kato M, Kiguchi Y. et al. Current status and challenges of endoscopic treatments for duodenal tumors. Digestion 2019; 99: 21-26
    CrossrefPubMedGoogle Scholar
  • 69 Shibagaki K, Ishimura N, Kinoshita Y. Endoscopic submucosal dissection for duodenal tumors. Ann Transl Med 2017; 5: 188
    CrossrefPubMedGoogle Scholar
  • 70 Yamamoto Y, Yoshizawa N, Tomida H. et al. Therapeutic outcomes of endoscopic resection for superficial non-ampullary duodenal tumor. Dig Endosc 2014; 26 (Suppl. 02) 50-56
    CrossrefPubMedGoogle Scholar
  • 71 Maple JT, Abu Dayyeh BK, Chauhan SS. et al. Endoscopic submucosal dissection. Gastrointest Endosc 2015; 81: 1311-1325
    CrossrefPubMedGoogle Scholar
  • 72 Deprez PH, Bergman JJ, Meisner S. et al. Current practice with endoscopic submucosal dissection in Europe: position statement from a panel of experts. Endoscopy 2010; 42: 853-858
    Article in Thieme ConnectPubMedGoogle Scholar
  • 73 Jung JH, Choi KD, Ahn JY. et al. Endoscopic submucosal dissection for sessile, non-ampullary duodenal adenomas. Endoscopy 2013; 45: 133-135
    Article in Thieme ConnectPubMedGoogle Scholar
  • 74 Matsumoto S, Yoshida Y. Selection of appropriate endoscopic therapies for duodenal tumors: an open-label study, single-center experience. World J Gastroenterol 2014; 20: 8624-8630
    CrossrefPubMedGoogle Scholar
  • 75 Yahagi N, Kato M, Ochiai Y. et al. Outcomes of endoscopic resection for superficial duodenal epithelial neoplasia. Gastrointest Endosc 2018; 88: 676-682
    CrossrefPubMedGoogle Scholar
  • 76 Honda T, Yamamoto H, Osawa H. et al. Endoscopic submucosal dissection for superficial duodenal neoplasms. Dig Endosc 2009; 21: 270-274
    CrossrefPubMedGoogle Scholar
  • 77 Hoteya S, Furuhata T, Takahito T. et al. Endoscopic submucosal dissection and endoscopic mucosal resection for non-ampullary superficial duodenal tumor. Digestion 2017; 95: 36-42
    CrossrefPubMedGoogle Scholar
  • 78 Hoteya S, Yahagi N, Iizuka T. et al. Endoscopic submucosal dissection for non-ampullary large superficial adenocarcinoma/adenoma of the duodenum: feasibility and long-term outcomes. Endosc Int Open 2013; 1: 2-7
    Article in Thieme ConnectPubMedGoogle Scholar
  • 79 Nonaka S, Oda I, Tada K. et al. Clinical outcome of endoscopic resection for nonampullary duodenal tumors. Endoscopy 2015; 47: 129-135
    Article in Thieme ConnectPubMedGoogle Scholar
  • 80 Pimentel-Nunes P, Dinis-Ribeiro M, Ponchon T. et al. Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 2015; 47: 829-854
    Article in Thieme ConnectPubMedGoogle Scholar
  • 81 Basford PJ, George R, Nixon E. et al. Endoscopic resection of sporadic duodenal adenomas: comparison of endoscopic mucosal resection (EMR) with hybrid endoscopic submucosal dissection (ESD) techniques and the risks of late delayed bleeding. Surg Endosc 2014; 28: 1594-1600
    CrossrefPubMedGoogle Scholar
  • 82 Santos-Antunes J, Baldaque-Silva F, Marques M. et al. Real-life evaluation of the safety, efficacy and therapeutic outcomes of endoscopic submucosal dissection in a Western tertiary centre. United Eur Gastroenterol J 2018; 6: 702-709
    CrossrefPubMedGoogle Scholar
  • 83 Esaki M, Haraguchi K, Akahoshi K. et al. Endoscopic mucosal resection vs endoscopic submucosal dissection for superficial non-ampullary duodenal tumors. World J Gastrointest Oncol 2020; 12: 918-930
    CrossrefPubMedGoogle Scholar
  • 84 Andrisani G, Di Matteo FM. Endoscopic full-thickness resection of duodenal lesions (with video). Surg Endosc 2020; 34: 1876-1881
    CrossrefPubMedGoogle Scholar
  • 85 Bauder M, Schmidt A, Caca K. Endoscopic full-thickness resection of duodenal lesions-a retrospective analysis of 20 FTRD cases. United Eur Gastroenterol J 2018; 6: 1015-1021
    CrossrefPubMedGoogle Scholar
  • 86 Schmidt A, Meier B, Cahyadi O. et al. Duodenal endoscopic full-thickness resection (with video). Gastrointest Endosc 2015; 82: 728-733
    CrossrefPubMedGoogle Scholar
  • 87 Schmidt A, Beyna T, Schumacher B. et al. Colonoscopic full-thickness resection using an over-the-scope device: a prospective multicentre study in various indications. Gut 2018; 67: 1280-1289
    CrossrefPubMedGoogle Scholar
  • 88 Ohata K, Nonaka K, Sakai E. et al. Novel technique of endoscopic full-thickness resection for superficial nonampullary duodenal neoplasms to avoid intraperitoneal tumor dissemination. Endosc Int Open 2016; 4: E784-E787
    Article in Thieme ConnectPubMedGoogle Scholar
  • 89 Irino T, Nunobe S, Hiki N. et al. Laparoscopic-endoscopic cooperative surgery for duodenal tumors: a unique procedure that helps ensure the safety of endoscopic submucosal dissection. Endoscopy 2015; 47: 349-351
    PubMedGoogle Scholar
  • 90 Kakushima N, Yoshida M, Yabuuchi Y. et al. Present status of endoscopic submucosal dissection for non-ampullary duodenal epithelial tumors. Clin Endosc 2020; 53: 652-658
    CrossrefPubMedGoogle Scholar
  • 91 Ojima T, Nakamori M, Nakamura M. et al. Laparoscopic and endoscopic cooperative surgery versus endoscopic submucosal dissection for the treatment of low-risk tumors of the duodenum. J Gastrointest Surg 2018; 22: 935-940
    CrossrefPubMedGoogle Scholar
  • 92 Ichikawa D, Komatsu S, Dohi O. et al. Laparoscopic and endoscopic co-operative surgery for non-ampullary duodenal tumors. World J Gastroenterol 2016; 22: 10424-10431
    CrossrefPubMedGoogle Scholar
  • 93 Ghilain JM, Dive C. Endoscopic laser therapy for small villous adenomas of the duodenum. Endoscopy 1994; 26: 308-310
    Article in Thieme ConnectPubMedGoogle Scholar
  • 94 Paraf F, Naveau S, Zourabichvili O. et al. Endoscopic laser therapy for duodenal villous adenoma. Dig Dis Sci 1989; 34: 1466-1467
    CrossrefPubMedGoogle Scholar
  • 95 Norton ID, Geller A, Petersen BT. et al. Endoscopic surveillance and ablative therapy for periampullary adenomas. Am J Gastroenterol 2001; 96: 101-106
    CrossrefPubMedGoogle Scholar
  • 96 Mlkvy P, Messmann H, Debinski H. et al. Photodynamic therapy for polyps in familial adenomatous polyposis – a pilot study. Eur J Cancer 1995; 31A: 1160-1165
    PubMedGoogle Scholar
  • 97 Ooka K, Celli R, Farrell JJ. Cryoablation of a duodenal adenoma with intramucosal carcinoma. VideoGIE 2017; 2: 244-246
    CrossrefPubMedGoogle Scholar
  • 98 Raphael KL, Benias PC, Trindade AJ. Salvage CryoBalloon cryotherapy ablation for a duodenal adenoma. Endoscopy 2020; 52: E189-E190
    Article in Thieme ConnectPubMedGoogle Scholar
  • 99 Apel D, Jakobs R, Spiethoff A. et al. Follow-up after endoscopic snare resection of duodenal adenomas. Endoscopy 2005; 37: 444-448
    Article in Thieme ConnectPubMedGoogle Scholar
  • 100 Alexander S, Bourke MJ, Williams SJ. et al. EMR of large, sessile, sporadic non-ampullary duodenal adenomas: technical aspects and long-term outcome (with videos). Gastrointest Endosc 2009; 69: 66-73
    CrossrefPubMedGoogle Scholar
  • 101 Koritala T, Zolotarevsky E, Bartley AN. et al. Efficacy and safety of the band and slough technique for endoscopic therapy of non-ampullary duodenal adenomas: a case series. Gastrointest Endosc 2015; 81: 985-988
    CrossrefPubMedGoogle Scholar
  • 102 Jaganmohan S, Lynch PM, Raju RP. et al. Endoscopic management of duodenal adenomas in familial adenomatous polyposis--a single-center experience. Dig Dis Sci 2012; 57: 732-737
    CrossrefPubMedGoogle Scholar
  • 103 Fawal H, Gambiez L, Raad A. et al. Management of duodenal adenomatosis in patients with familial adenomatous polyposis. Ann Chir 2003; 128: 594-598
    CrossrefPubMedGoogle Scholar
  • 104 Min YW, Min B-H, Kim ER. et al. Efficacy and safety of endoscopic treatment for nonampullary sporadic duodenal adenomas. Dig Dis Sci 2013; 58: 2926-2932
    CrossrefPubMedGoogle Scholar
  • 105 Navaneethan U, Lourdusamy D, Mehta D. et al. Endoscopic resection of large sporadic non-ampullary duodenal polyps: efficacy and long-term recurrence. Surg Endosc 2014; 28: 2616-2622
    CrossrefPubMedGoogle Scholar
  • 106 Abbass R, Rigaux J, Al-Kawas FH. Non-ampullary duodenal polyps: characteristics and endoscopic management. Gastrointest Endosc 2010; 71: 754-759
    CrossrefPubMedGoogle Scholar
  • 107 Aschmoneit-Messer I, Richl J, Pohl J. et al. Prospective study of acute complication rates and associated risk factors in endoscopic therapy for duodenal adenomas. Surg Endosc 2015; 29: 1823-1830
    CrossrefPubMedGoogle Scholar
  • 108 Tsiamoulos ZP, Peake ST, Bourikas LA. et al. Endoscopic mucosal ablation: a novel technique for a giant non-ampullary duodenal adenoma. Endoscopy 2013; 45 (Suppl. 02) E12-E13
    Article in Thieme ConnectPubMedGoogle Scholar
  • 109 Kedia P, Brensinger C, Ginsberg G. Endoscopic predictors of successful endoluminal eradication in sporadic duodenal adenomas and its acute complications. Gastrointest Endosc 2010; 72: 1297-1301
    CrossrefPubMedGoogle Scholar
  • 110 Manner H, May A, Rabenstein T. et al. Prospective evaluation of a new high-power argon plasma coagulation system (hp-APC) in therapeutic gastrointestinal endoscopy. Scand J Gastroenterol 2007; 42: 397-405
    CrossrefPubMedGoogle Scholar
  • 111 Eswaran SL, Sanders M, Bernadino KP. et al. Success and complications of endoscopic removal of giant duodenal and ampullary polyps: a comparative series. Gastrointest Endosc 2006; 64: 925-932
    CrossrefPubMedGoogle Scholar
  • 112 Leblanc S, Vienne A, Dhooge M. et al. Early experience with a novel hemostatic powder used to treat upper GI bleeding related to malignancies or after therapeutic interventions (with videos). Gastrointest Endosc 2013; 78: 169-175
    CrossrefPubMedGoogle Scholar
  • 113 Naseer M, Lambert K, Hamed A. et al. Endoscopic advances in the management of non-variceal upper gastrointestinal bleeding: A review. World J Gastrointest Endosc 2020; 12: 1-16
    CrossrefPubMedGoogle Scholar
  • 114 Kato M, Sasaki M, Mizutani M. et al. Predictors of technical difficulty with duodenal ESD. Endosc Int Open 2019; 7: E1755-E1760
    Article in Thieme ConnectPubMedGoogle Scholar
  • 115 Kato M, Ochiai Y, Fukuhara S. et al. Clinical impact of closure of the mucosal defect after duodenal endoscopic submucosal dissection. Gastrointest Endosc 2019; 89: 87-93
    CrossrefPubMedGoogle Scholar
  • 116 Hoteya S, Kaise M, Iizuka T. et al. Delayed bleeding after endoscopic submucosal dissection for non-ampullary superficial duodenal neoplasias might be prevented by prophylactic endoscopic closure: analysis of risk factors. Dig Endosc 2015; 27: 323-330
    CrossrefPubMedGoogle Scholar
  • 117 Tashima T, Ohata K, Sakai E. et al. Efficacy of an over-the-scope clip for preventing adverse events after duodenal endoscopic submucosal dissection: a prospective interventional study. Endoscopy 2018; 50: 487-496
    Article in Thieme ConnectPubMedGoogle Scholar
  • 118 Ohata K, Sakai E, Suzuki Y. et al. Risk factors of delayed bleeding after endoscopic resection of superficial non-ampullary duodenal epithelial tumors and prevention by over-the-scope and conventional clipping. Dig Endosc 20.05.2020; DOI: 10.1111/den.13729.
    CrossrefPubMedGoogle Scholar
  • 119 Kakushima N, Kanemoto H, Tanaka M. et al. Treatment for superficial non-ampullary duodenal epithelial tumors. World J Gastroenterol 2014; 20: 12501-12508
    CrossrefPubMedGoogle Scholar
  • 120 Gaspar JP, Stelow EB, Wang AY. Approach to the endoscopic resection of duodenal lesions. World J Gastroenterol 2016; 22: 600-617
    CrossrefPubMedGoogle Scholar
  • 121 Farnell MB, Sakorafas GH, Sarr MG. et al. Villous tumors of the duodenum: reappraisal of local vs. extended resection. . J Gastrointest Surg 2000; 4: 13-21, discussion 22-23
    CrossrefPubMedGoogle Scholar
  • 122 Perez A, Saltzman JR, Carr-Locke DL. et al. Benign non-ampullary duodenal neoplasms. J Gastrointest Surg 2003; 7: 536-541
    CrossrefPubMedGoogle Scholar
  • 123 Bjork KJ, Davis CJ, Nagorney DM. et al. Duodenal villous tumors. Arch Surg 1990; 125: 961-965
    CrossrefPubMedGoogle Scholar
  • 124 Xu M, Wu J, Yu L. et al. Surgical versus endoscopic resection of large sessile duodenal and papillary lesions. Eur J Gastroenterol Hepatol 2020; 32: 48-53
    CrossrefPubMedGoogle Scholar
  • 125 Bartel MJ, Puri R, Brahmbhatt B. et al. Endoscopic and surgical management of nonampullary duodenal neoplasms. Surg Endosc 2018; 32: 2859-2869
    CrossrefPubMedGoogle Scholar
  • 126 Hassan C, Ponchon T, Bisschops R. et al. European Society of Gastrointestinal Endoscopy (ESGE) Publications Policy – Update 2020. Endoscopy 2020; 52: 123-126
    Article in Thieme ConnectPubMedGoogle Scholar