Treatment of non-ampullary duodenal epithelial tumors: Does phenotype matter?

10.1055/a-1477-3186Although non-ampullary duodenal epithelial tumors (NADETs) are relatively rare in the general population, opportunities for endoscopic detection and treatment of them have been increasing due to advances in endoscopic equipment and awareness of the disease [1]. Because the prognosis for invasive duodenal carcinoma is dismal and surgical treatment with pancreatoduodenectomy can result in morbidity and death, less invasive prophylactic treatment of NADETs with endoscopic resection significantly benefits patients. Nevertheless, endoscopic treatment of NADETs is often difficult because the narrow and tortuous duodenal lumen restricts endoscopic maneuvers and thin duodenal walls and secretion of bile and pancreatic juice into the duodenal lumen induce severe delayed adverse events (AEs), such as bleeding and perforation [2]. Accordingly, it is important to establish practical indications for when NADETs should or should need be treated with endoscopic resection.

Publikationsverlauf

Artikel online veröffentlicht:
16. August 2021

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