Subscribe to RSS
Endoscopic management of postesophagectomy leak with modified clip-and-loop technique
A 75-year-old woman with carcinoma of the lower esophagus underwent esophagectomy with proximal gastrectomy. On the 6th day after surgery, she developed breathlessness with chest pain and high-grade fever. Computed tomography (CT) of the chest showed a leak from the anastomotic site tracking into the right pleura ([Fig. 1]). Upper gastrointestinal endoscopy showed dehiscence of approximately 1 cm at the anastomotic site ([Fig. 2]). After multidisciplinary discussion, endoscopic rent closure was planned. The edges of the defect were ablated using argon plasma coagulation. Due to angulation, complete apposition of the defect using clips was not feasible. Resolution clips (Boston Scientific, Marlborough, Massachusetts, USA) were applied to the edges of the defect. An endoloop (Olympus Medical, Tokyo, Japan) was applied to tie the clips together to close the defect completely ([Video 1]) ([Fig. 3]). There was a decrease in the right pleural drain output, with contrast swallow showing no leak on day 5 ([Fig. 4]). Repeat endoscopy on day 14 showed a completely healed defect at the anastomotic site ([Fig. 5]).
Video 1 Closure of postesophagectomy leak using a modified clip-and-loop technique.
The “loop clip” technique for closure of defects after endoscopic submucosal dissection was initially described by Sakamoto et al. in 2008, where a loop is attached to the edges of a defect with clips and subsequently tightened to close the defect  . Other techniques that have been described for gastrotomy closure are the King technique and Queen technique  , in which a double-channel endoscope or multiple loops are required. The modified clip-and-loop technique we used has been described by Luigiano et al. for closure of tracheo-esophageal fistula . In our patient the size of the defect was small, making it difficult to attach a loop to the edges of the defect. Complete closure using clips was difficult due to the angulation and free lower edge. Hence the clips were tied together to ensure approximation and complete closure of the defect.
Endoscopy E-Videos is an open access online section, reporting on interesting cases and new techniques in gastroenterological endoscopy. All papers include a high quality video and all contributions are freely accessible online. Processing charges apply (currently EUR 375), discounts and wavers acc. to HINARI are available.
This section has its own submission website at https://mc.manuscriptcentral.com/e-videos
Article published online:
08 October 2021
© 2021. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
- 1 Sakamoto N, Beppu K, Matsumoto K. et al. “Loop Clip”, a new closure device for large mucosal defects after EMR and ESD. Endoscopy 2008; 40: E97-E98
- 2 Nomura T, Kobayashi M, Morikawa T. et al. Clip-fixed endoloop: an efficacious new method for mucosal defect closure. Endoscopy 2018; 50: E126-E127
- 3 Hookey LC, Khokhotva V, Bielawska B. et al. The Queen’s closure: a novel technique for closure of endoscopic gastrotomy for natural-orifice transluminal endoscopic surgery. Endoscopy 2009; 41: 149-153
- 4 Ryska O, Martinek J, Filipkova T. et al. Single loop-and-clips technique (KING closure) for gastrotomy closure after transgastric ovariectomy: a survival experiment. Wideochir Inne Tech Maloinwazyjne 2012; 7: 233-239
- 5 Luigiano C, Ferrara F, Polifemo AM. et al. Endoscopic closure of esophageal fistula using a novel “clips and loop” method. Endoscopy 2009; 41: E249-E250