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Synlett 2022; 33(07): 694-698
DOI: 10.1055/a-1770-7922
DOI: 10.1055/a-1770-7922
letter
Bismuth(III) Triflate-Catalyzed Intermolecular Cyclization of Phenols with Diols: Direct Access to O-Heterocycles
Authors
This work was supported by Mitsubishi Chemical Corporation.
Abstract
A direct access to O-heterocycles by Bi(OTf)3-catalyzed intermolecular cyclization of phenols with diols is described. Catalytic dehydrative tandem formation of C–O and C–C bonds was achieved by using a Bi(OTf)3 catalyst without any additives. The catalytic intermolecular cyclization of phenols with various diols proceeded to give the corresponding chromanes in up to 91% yield and/or pyran derivatives in up to 66% yield.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-1770-7922.
- Supporting Information (PDF)
Publication History
Received: 20 January 2022
Accepted after revision: 14 February 2022
Accepted Manuscript online:
14 February 2022
Article published online:
10 March 2022
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For syntheses of ethers by Bi(OTf)3 catalysis, see:
For acid-catalyzed 1,3-shifts, see:
For Bi(OTf)3-catalyzed cyclizations, see: