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DOI: 10.1055/a-1916-8878
To screen or not to screen: Reply to “Long-term results of an endoscopic screening program for superficial esophageal cancer in patients with head and neck squamous cell carcinoma”
Esophageal second primary tumors (ESPTs) frequently occur in patients with head and neck squamous cell carcinoma (HNSCC), with strongly varying incidences worldwide [1] [2]. Therefore, different screening strategies are used, from annual screening for every patient with HNSCC in some countries, including Brazil, to no standardized esophageal screening in Western countries. With great interest, we have read the article by Nobre Moura et al. [3] investigating endoscopic screening for superficial esophageal cancer in patients with HNSCC in Brazil. We compliment the authors for the large sample size of 1,888 patients with HNSCC with a relatively long median follow-up time. The authors reported a detection rate of 7.9 % ESPTs by annual endoscopic screening and most ESPTs (77.8 %) were early-stage lesions. The detection of advanced ESPTs was associated with a significantly shorter overall survival in patients with HNSCC, while early ESPTs showed no survival difference compared to those with HNSCC only. These results are promising and emphasize the need for further studies about screening patients with HNSCC for ESPTs.
Publikationsverlauf
Artikel online veröffentlicht:
17. Oktober 2022
© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
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