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CC BY-NC-ND 4.0 · Endosc Int Open 2022; 10(12): E1583-E1588
DOI: 10.1055/a-1954-0110
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Endoscopic treatment of intussusception due to small intestine polyps in patients with Peutz-Jeghers Syndrome

Kunihiko Oguro
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Hirotsugu Sakamoto
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Tomonori Yano
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Yohei Funayama
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Masafumi Kitamura
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Manabu Nagayama
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Keijiro Sunada
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Alan Kawarai Lefor
2   Department of Surgery, Jichi Medical University, Tochigi, Japan
,
Hironori Yamamoto
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
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Abstract

Background and study aims Intussusception caused by intestinal polyps in patients with Peutz-Jeghers syndrome usually requires laparotomy. Patients following successful endoscopic reduction using double-balloon endoscopy (DBE) have been reported. The aim of this study was to evaluate the feasibility of endoscopic treatment of intussusception.

Patients and methods We retrospectively reviewed patients who underwent DBE for intussusception due to small intestine polyps in patients with Peutz-Jeghers syndrome from January 2004 to June 2020.

Results Twenty-seven (antegrade 22, retrograde 5) DBEs were performed in 19 patients with 25 sites of intussusception identified during the study period. If the intussusception remained once the endoscope reached the site, endoscopic reduction of the intussusception was performed as needed (15 sites). Ultimately, endoscopic resections (8 sites) or ischemic polypectomies (16 sites) of the polyp causing the intussusception were completed at 24 sites. Only one site could not be treated endoscopically and was treated surgically. The final per-site and per-patient success rates of endoscopic treatment were 96 % (24/25) and 95 % (18/19) respectively. Two patients developed mild acute pancreatitis and one patient developed intussusception after the procedures, both of which were treated non-operatively.

Conclusions Endoscopic treatment of intussusception is feasible to avoid laparotomy in patients with Peutz-Jeghers syndrome.



Publication History

Received: 16 May 2022

Accepted after revision: 30 September 2022

Accepted Manuscript online:
30 September 2022

Article published online:
15 December 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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Comment to this article:

Endoscopy International Open – recently publishedEndoscopy 2023; 55(01): 105-105
DOI: 10.1055/a-1966-9237

 

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