Successful omental patch for huge colonic perforation using regraspable clip

A 79-year-old woman with a 20-mm early-stage colorectal cancer of the ascending colon underwent endoscopic submucosal dissection (ESD). A novel complete closure using a regraspable clip (Sureclip; Micro-Tech Co., Ltd, Nanjing, China) ([Fig. 1]) was applied for a large perforation that occurred during procedure.

Fig. 1 The clip is re-graspable and re-openable.

Initially the intra-abdominal fatty tissue of the greater omentum was grasped and pulled by the clip into the colon lumen. Subsequently, the clip was opened, and the mucosa re-grasped at both ends of the perforation with the retracting omentum. After confirmation that the omentum and mucosa at both ends were grasped together, the clip was released.

The first clip was then used as an anchor, and it was held down with a transparent attachment to narrow the shape of the perforated site and shorten the diameter. Then, additional clips were placed one after another with fatty tissue drawn into the colon lumen in the same manner ([Video 1], [Fig. 2]). In this way, we succeeded in completing the closure ([Fig. 3]).

Video 1 Successful omental patch for huge colonic perforation using regraspable clip.

Fig. 2 Shema of this procedure. a Intra-abdominal fat tissue was pulled into the lumen. b Both ends of the mucosa were clipped with drawn fat tissue. c The first clip was pressed down with a transparent attachment to narrow the shape of the perforation site. d Then, after fat was drawn with sufficient suction, mucosa was clipped at both ends with fat. e Additional clips were applied in the same manner. f Successfully completed closure.

Fig. 3 Endoscopic views. a A large perforation occurred. b The omentum from within the abdomen was grasped. c Omentum was pulled into the colon lumen. d Mucosa was re-grasped at both ends together with omentum. e Additional clipping in the same manner. f Complete closure.

Postoperatively, the patient was conservatively managed and discharged 6 days after ESD. We also confirmed complete closure by follow-up endoscopy performed 2 months later ([Fig. 4]).

Fig. 4 Follow-up endoscopy (2 months later) showed complete closure and epithelialization.

During the ESD, a large perforation of more than 10 mm occurred, but using the Sureclip, the perforation was closed completely by drawing fatty tissue into the lumen of the colon, and the patient was managed conservatively without any major problems.

There have been several reports showing complete closure of colonic perforations. However, all of them required the use of specific devices such as the endoloop [1], endoscopic band ligation [2], and the OTSC clip [3]. In our case, it was simpler to use only Sureclips. This method may be useful in sites where the scope can easily approach fatty tissue of the greater omentum.

Endoscopy_UCTN_Code_CPL_1AJ_2AD

Publication History

Article published online:
09 February 2023

• References

• 1 Galtieri PA, Auriemma F, Maselli R. et al. Omental patch for closure of a cecal perforation during endoscopic resection of a laterally spreading tumor. Endoscopy 2019; 51: E237-E238
• 2 Angsuwatcharakon P, Thienchanachaiya P, Pantongrag-Brown L. Endoscopic band ligation to create an omental patch for closure of a colonic perforation. Endoscopy 2012; 44: E90-E91
• 3 Parodi A, Repici A, Pedroni A. et al. Endoscopic management of GI perforations with a new over-the-scope clip device. Gastrointest Endosc 2010; 72: 881-886