Abstract
α-Haloboron compounds are very versatile synthons in organic synthesis. They can be
transformed into several kinds of skeletons via Matteson homologation reaction, cross-coupling
or other strategies based on the carbon–halo or carbon–boron bond. In recent years,
many important advances have been achieved in the upstream and downstream chemistry
of these compounds. This review comprehensively summarizes their current synthetic
methods and asymmetric couplings with nickel catalysts.
1 Introduction
2 The Preparation of α-Haloboron Compounds
3 The Asymmetric Transformation of α-Haloboron Compounds
4 Conclusion
Key words
boron chemistry - α-haloboron compounds - asymmetric coupling - nickel catalysis -
homologation reaction
