Endoscopic ultrasound-guided drainage of a complex kidney abscess penetrating to the gallbladder and right liver lobe

A 64-year-old woman with a past medical history of poorly controlled diabetes, morbid obesity, hypertension, and status post-oncological treatment for metastatic sigmoid colon cancer was admitted to the surgery department due to a 50 × 40 × 43-mm abscess in the right kidney on computed tomography (CT) ([Fig. 1]). The abscess penetrated the gallbladder, causing its perforation. It also penetrated the liver and was causing renal artery infiltration with pseudoaneurysm formation (21 mm and 16 mm in diameter) ([Fig. 2]). The patient was clinically and biochemically septic. CT ruled out other sites of abscess. Due to significant associated co-morbidities, poor general status, and poor percutaneous access, neither a standard surgical intervention nor percutaneous drainage was feasible.

Fig. 1 The 50 × 40 × 43-mm abscess in the right kidney, penetrating into the gallbladder causing its perforation.

Fig. 2 Endoscopic ultrasound-guided lumen-apposing metal stent (20 mm × 16 mm) placement for left kidney drainage through the gallbladder, followed by nasogastric tube placement.

As there was a connection between the kidney abscess and perforated gallbladder, endoscopic ultrasound (EUS)-guided drainage was performed under general anesthesia using a linear echoendoscope ([Video 1]). Through transduodenal access after endosonographic visualization of the gallbladder, fine-needle aspiration (FNA) with a 19G FNA needle was performed. The aspired purulent content mixed with bile of the gallbladder confirmed the position. A 0.035-inch guidewire was advanced through the needle and looped in the abscess cavity under X-ray control. Then, the tract was dilated with a 10-Fr cystotome, followed by placement of a 20  ×  16-mm cautery-enhanced lumen-apposing metal stent (LAMS). Immediately, purulent content outflow was observed from the stent lumen. The procedure was concluded with placement of a 7-Fr nasogastric tube through the LAMS lumen for active abscess lavage (50 ml of saline every 6 hours).

Video 1 Endoscopic ultrasound-guided drainage of a complex kidney abscess through perforated gallbladder using lumen-apposing metal stent with double pigtail.

After 3 weeks of active transmural drainage, symptoms resolved and laboratory parameters normalized. CT showed a collection decrease to 3 mm, given that the nasogastric tube was replaced with a 7-Fr × 7-cm double-pigtail stent. The patient was discharged and followed up in outpatient settings. After 5 months, CT showed a collection size of 21 × 10 mm (decrease> 50 %) and a healed gallbladder wall during follow-up endoscopic assessment ([Fig. 3]). One year after the procedure, the patient remains asymptomatic, without collection, on LAMS stent and permanent double-pigtail drainage to prevent recurrence ([Fig. 4]).

Fig. 3 Computed tomography performed 5 months after the procedure: successful endoscopic treatment (collection size 21 × 10 mm; decrement > 50 %).

Fig. 4 Surveillance esophagogastroduodenoscopy 12 months after the procedure: healed gallbladder wall; patient remains asymptomatic.

This case is important for three reasons. First, we show how a complex kidney abscess penetrating the gallbladder and liver can be successfully managed endoscopically. Second, EUS-guided drainage of a peritoneal cavity abscess might be an optimal alternative therapy for patients with multiple comorbidities, at high risk for life-threatening recurrent sepsis, and are poor surgical candidates. Lastly, similar to the management of other types of recurrent collections, long-term transmural drainage with an indwelling double-pigtail plastic stent seems to be an option for this group of patients [1].

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Artikel online veröffentlicht:
24. Oktober 2023

• Reference

• 1 Gkolfakis P, Bourguignon A, Arvanitakis M. et al. Indwelling double-pigtail plastic stents for treating disconnected pancreatic duct syndrome-associated peripancreatic fluid collections: long-term safety and efficacy. Endoscopy 2021; 53: 1141-1149