Abstract
Background This study aimed to assess the feasibility and safety of performing cholangiopancreatoscopy-assisted
endoscopic mucosal resection (CA-EMR) for biliopancreatic intraductal lesions.
Methods Special electrocautery snares and injection needles that can pass through the working
channel of a single-operator cholangiopancreatoscope were developed. Between November
2023 and April 2024, we performed CA-EMR for two patients with gallbladder polyps,
one patient with a neoplastic lesion in the common bile duct (CBD), and one patient
with a neoplastic lesion in the main pancreatic duct. The technical success rate and
adverse events were recorded.
Results All four CA-EMR procedures were performed successfully. Postoperative pathology revealed
inflammatory gallbladder polyps in two patients, low grade intraepithelial neoplasia
of the CBD in one patient, and intraductal papillary mucinous neoplasm (IPMN) in one
patient. The patient with IPMN experienced mild postoperative pancreatitis and recovered
after conservative treatment. No adverse events were encountered in the other three
CA-EMR procedures.
Conclusion This study preliminarily confirmed the feasibility and safety of CA-EMR for treating
biliopancreatic intraductal lesions.
