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CC BY 4.0 · Sustainability & Circularity NOW 2025; 02: a25398742
DOI: 10.1055/a-2539-8742
Original Article

Phosphate Recovery at “A Campingflight to Lowlands Paradise”: Organic Micropollutant Uptake and Environmental Risk Assessment

Authors

  • Steven Beijer

    1   Van ‘t Hoff Institute for Molecular Sciences, University of Amsterdam, PO Box 94157, 1090 GD Amsterdam, the Netherlands

  • Noelia Salgueiro-Gonzalez

    2   Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri - IRCCS, Via Mario Negri 2, 20156 Milan, Italy

  • Sara Castiglioni

    2   Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri - IRCCS, Via Mario Negri 2, 20156 Milan, Italy

  • Juan C. Gerlein

    3   SEMiLLA Sanitation, Innovatieweg 4, 7007 CD Doetinchem, the Netherlands

  • Peter Scheer

    3   SEMiLLA Sanitation, Innovatieweg 4, 7007 CD Doetinchem, the Netherlands

  • G Bas de Jong

    1   Van ‘t Hoff Institute for Molecular Sciences, University of Amsterdam, PO Box 94157, 1090 GD Amsterdam, the Netherlands

  • J Chris Slootweg 

    1   Van ‘t Hoff Institute for Molecular Sciences, University of Amsterdam, PO Box 94157, 1090 GD Amsterdam, the Netherlands

Funding information We gratefully acknowledge funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No. 818309 (www.lex4bio.eu) and the European Union’s Justice Programme – Drugs Policy under grant agreement No. 861602 (www.euseme.eu).
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Abstract

Despite increasing interest in struvite as a renewable phosphate source and fertilizer, research into real-world cases of organic micropollutant contamination in struvite is limited, with no studies addressing the inclusion of illicit substances. Urine is an ideal matrix to precipitate struvite from and study its organic contamination, as it contains the majority of organic contaminants as well as nutrients excreted by humans. As such, we devised a worst-case scenario in terms of organic contamination by collecting urine at the Dutch festival “A Campingflight to Lowlands Paradise” and precipitating struvite on-site in three batches. This festival setting provided a highly contaminated urine source, offering extreme conditions to evaluate to what extent such contamination translates to struvite and if that struvite would be safe to use as fertilizer. Surveys on consumed pharmaceuticals and illicit drugs by participants guided subsequent analysis of urine and struvite samples, which was performed using liquid chromatography–tandem mass spectrometry (LC–MS/MS). Concentrations of organic contaminants in the urine corresponded well with the survey results and were found in a broad range from <1 to over 34,000 ng mL−1. Concentrations found in the struvite precipitates generally showed a correlation proportional to contaminant K oc values with those found in their respective urine source and were predominantly in the range of 1–100 ng g−1, with an outlier at 1081 ng g−1. Based on these numbers, the environmental risk associated with using the precipitated struvite as renewable phosphate fertilizer was classified as insignificant in all cases. After 100 years of hypothetical Lowlands-struvite application as fertilizer, only paracetamol and MDMA would be classified as having low risk. All other analytes remain an insignificant environmental risk, showing struvite to be a safe, renewable phosphate source in terms of organic contamination.

Keywords

Nutrient recycling - Struvite recovery - Target analysis - Organic micropollutants - Environmental risk assessment

Supplementary Material



Publication History

Received: 27 November 2024

Accepted after revision: 12 February 2025

Accepted Manuscript online:
14 February 2025

Article published online:
05 March 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

Bibliographical Record
Steven Beijer, Noelia Salgueiro-Gonzalez, Sara Castiglioni, Juan C. Gerlein, Peter Scheer, G Bas de Jong, J Chris Slootweg. Phosphate Recovery at “A Campingflight to Lowlands Paradise”: Organic Micropollutant Uptake and Environmental Risk Assessment. Sustainability & Circularity NOW 2025; 02: a25398742.
DOI: 10.1055/a-2539-8742
 

  • References

  • 1 Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. Garland Science; New York: 2008
    Search in Google Scholar
  • 2 Jupp AR, Beijer S, Narain GC, Schipper W, Slootweg JC. Chem. Soc. Rev. 2021; 50: 87-101
    Search in Google Scholar
  • 3 Filipelli GM. Elements 2008; 4: 89-95
    Search in Google Scholar
  • 4 Asimov I. In Mag. Fantasy Sci. Fict.. Mercury Press; Oklahoma City: 1959
    Search in Google Scholar
  • 5 Cordell D, Drangert J, White S. Glob. Environ. Chang. 2009; 19: 292-305
    Search in Google Scholar
  • 6 van Kauwenbergh SJ, Stewart M, Mikkelsen R. Better Crop. 2013; 97: 18-20
    Search in Google Scholar
  • 7 European Commission. Critical Raw Materials Resilience: Charting a Path towards Greater Security and Sustainability. European Commission; 2020
    Search in Google Scholar
  • 8 Rittmann BE, Mayer B, Westerhoff P, Edwards M. Chemosphere 2011; 84: 846-853
    Search in Google Scholar
  • 9 Gustavsson J, Cederberg C, Sonesson U, van Otterdijk R, Meybeck A. Global Food Losses and Food Wastes: Extent, Causes and Prevention. Rome: 2011
    Search in Google Scholar
  • 10 Scherhaufer S, Moates G, Hartikainen H, Waldron K, Obersteiner G. Waste Manage. 2018; 77: 98-113
    Search in Google Scholar
  • 11 Cordell D, White S. Sustainability 2011; 3: 2027-2049
    Search in Google Scholar
  • 12 van Dijk KC, Lesschen JP, Oenema O. Sci. Total Environ. 2016; 542: 1078-1093
    Search in Google Scholar
  • 13 Withers PJ. A, van Dijk KC, Neset TS. S, Nesme T, Oenema O, Rubæk GH, Schoumans OF, Smit B, Pellerin S. Ambio 2015; 44: 193-206
    Search in Google Scholar
  • 14 Egle L, Rechberger H, Krampe J, Zessner M. Sci. Total Environ. 2016; 571: 522-542
    Search in Google Scholar
  • 15 Talboys PJ, Heppell J, Roose T, Healey JR, Jones DL, Withers PJ. A. Plant Soil 2016; 401: 109-123
    Search in Google Scholar
  • 16 Huygens D, Saveyn H, Tonini D, Eder P, Sancho LD. Technical Proposals for Selected New Fertilising Materials under the Fertilising Products Regulation (Regulation (EU) 2019/1009): Process and Quality Criteria, and Assessment of Environmental and Market Impacts for Precipitated Phosphate Salts & Derivates. 2019
    Search in Google Scholar
  • 17 Shaddel S, Bakhtiary-Davijany H, Kabbe C, Dadgar F, Østerhus SW. Sustainability 2019; 11: 1-12
    Search in Google Scholar
  • 18 Muys M, Phukan R, Brader G, Samad A, Moretti M, Haiden B, Pluchon S, Roest K, Vlaeminck SE, Spiller M. Sci. Total Environ. 2021; 756: 143726
    Search in Google Scholar
  • 19 Snoeyink VL, Jenkins D. Water Chemistry. John Wiley & Sons, Inc.; New York: 1980
    Search in Google Scholar
  • 20 Ohlinger KN, Young TM, Schroeder ED. Water Res. 1998; 32: 3607-3614
    Search in Google Scholar
  • 21 Booker NA, Priestley AJ, Fraser IH. Environ. Technol. 1999; 20: 777-782
    Search in Google Scholar
  • 22 Buchanan JR, Mote CR, Robinson RB. Trans. Am. Soc. Agric. Eng. 1994; 37: 617-621
    Search in Google Scholar
  • 23 Kehrein P, Van Loosdrecht M, Osseweijer P, Garfí M, Dewulf J, Posada J. Environ. Sci.: Water Res. Technol. 2020; 6: 877-910
    Search in Google Scholar
  • 24 Cornel P, Schaum C. Water Sci. Technol. 2009; 59: 1069-1076
    Search in Google Scholar
  • 25 Doyle JD, Parsons SA. Water Res. 2002; 36: 3925-3940
    Search in Google Scholar
  • 26 Le Corre KS, Valsami-Jones E, Hobbs P, Parsons SA. Crit. Rev. Environ. Sci. Technol. 2009; 39: 433-477
    Search in Google Scholar
  • 27 Crutchik D, Garrido JM. Chemosphere 2016; 154: 567-572
    Search in Google Scholar
  • 28 Ronteltap M, Maurer M, Gujer W. Water Res. 2007; 41: 1859-1868
    Search in Google Scholar
  • 29 de Boer MA, Hammerton M, Slootweg JC. Water Res. 2018; 133: 19-26
    Search in Google Scholar
  • 30 STOWA. Verkenning van de Kwaliteit van Struviet Uit de Communale Afvalwaterketen. 2015
    Search in Google Scholar
  • 31 Friedler E, Butler D, Alfiya Y. In Source Sep. Decentralization Wastewater Manag. Larsen TA, Udert KM, Lienert J. Eds IWA Publishing; 2013. pp 241-257
    Search in Google Scholar
  • 32 Udert KM, Larsen TA, Gujer W. Water Sci. Technol. 2006; 54: 413-420
    Search in Google Scholar
  • 33 Larsen TA, Gujer W. Water Sci. Technol. 1996; 34: 87-94
    Search in Google Scholar
  • 34 Lienert J, Bürki T, Escher BI. Water Sci. Technol. 2007; 56: 87-96
    Search in Google Scholar
  • 35 Liu Z, Zhao Q, Wang K, Lee D, Qiu W, Wang J. J. Environ. Sci. 2008; 20: 1018-1024
    Search in Google Scholar
  • 36 Etter B, Tilley E, Khadka R, Udert KM. Water Res. 2011; 45: 852-862
    Search in Google Scholar
  • 37 Liu X, Hu Z, Mu J, Zang H, Liu L. Environ. Technol. 2014; 35: 2781-2787
    Search in Google Scholar
  • 38 Petrie B, Youdan J, Barden R, Kasprzyk-Hordern B. J. Chromatogr. A 2016; 1431: 64-78
    Search in Google Scholar
  • 39 Drugbank, webpage on cocaethylene, can be found under https://go.drugbank.com/metabolites/DBMET00645
  • 40 Grabic R, Ivanová L, Kodešová R, Grabicová K, Vojs Staňová A, Imreová Z, Drtil M, Bodík I. Water Res. 2022; 220 118651
    Search in Google Scholar
  • 41 Dinis-Oliveira RJ. Forensic Sci. Res. 2017; 2: 2-10
    Search in Google Scholar
  • 42 Drugbank, webpage on norKetamine, can be found under https://go.drugbank.com/metabolites/DBMET00189
  • 43 Avdeef A, Berger CM, Brownell C. Pharm. Res. 2000; 17: 85-89
    Search in Google Scholar
  • 44 Settimo L, Bellman K, Knegtel RM. A. Pharm. Res. 2014; 31: 1082-1095
    Search in Google Scholar
  • 45 Malev O, Lovrić M, Stipaničev D, Repec S, Martinović-Weigelt D, Zanella D, Ivanković T, Sindičić Đuretec V, Barišić J, Li M, Klobučar G. Environ. Pollut. 2020; 266 115162
    Search in Google Scholar
  • 46 Ahjel SW, Lupuleasa D. Farmacia 2009; 57: 290-300
    Search in Google Scholar
  • 47 Drugbank, webpage on atorvastatine, can be found under https://go.drugbank.com/drugs/DB01076
  • 48 Kirla KT, Erhart C, Groh KJ, Stadnicka-Michalak J, Eggen RI. L, Schirmer K, Kraemer T. Toxicol. Appl. Pharmacol. 2021; 419: 115483
    Search in Google Scholar
  • 49 Bijlsma L, Celma A, Castiglioni S, Salgueiro-González N, Bou-Iserte L, Baz-Lomba JA, Reid MJ, Dias MJ, Lopes A, Matias J, Pastor-Alcañiz L, Radonić J, Turk Sekulic M, Shine T, van Nuijs AL. N, Hernandez F, Zuccato E. Sci. Total Environ. 2020; 725 138376
    Search in Google Scholar
  • 50 Helfer AG, Michely JA, Weber AA, Meyer MR, Maurer HH. Anal. Chim. Acta 2015; 891: 221-233
    Search in Google Scholar
  • 51 Castiglioni S, Zuccato E, Crisci E, Chiabrando C, Fanelli R, Bagnati R. Anal. Chem. 2006; 78: 8421-8429
    Search in Google Scholar
  • 52 Castiglioni S, Davoli E, Riva F, Palmiotto M, Camporini P, Manenti A, Zuccato E. Water Res. 2018; 131: 287-298
    Search in Google Scholar
  • 53 Salgueiro-González N, Zuccato E, Castiglioni S. Sci. Total Environ. 2022; 843: 156982
    Search in Google Scholar
  • 54 Rijksdienst voor Ondernemend Nederland. Hoeveel Mest Gebruiken. Hoe Rekent u Dat Uit?. 2019
    Search in Google Scholar
  • 55 Commissie Deskundigen Meststoffenwet. Protocol Beoordeling Stoffen Meststoffenwet. Versie 3.2. Wageningen: 2016
    Search in Google Scholar
  • 56 European Commission. Technical Guidance Document on Risk Assessment Part III, Version 2, 2003. 2003
    Search in Google Scholar
  • 57 NORMAN. Deriving Environmental Quality Standards for Chemical Substances in Surface Waters. 2022
    Search in Google Scholar
  • 58 Thomaidi VS, Stasinakis AS, Borova VL, Thomaidis NS. J. Hazard. Mater. 2015; 283: 740-747
    Search in Google Scholar
  • 59 Smit CE. Effecten van Drugs Op Het Waterecosysteem. 2015
    Search in Google Scholar
  • 60 Janssen MP. M, Traas TP, Rila J.-P, van Vlaardingen PL. A. 2004: 1-35
  • 61 Wennmalm Å, Gunnarsson B. Environ. Int. 2009; 35: 775-777
    Search in Google Scholar
  • 62 Trimbos. Webpage on use of drugs in the Netherlands in 2022, can be found under https://www.trimbos.nl/actueel/nieuws/nieuwe-cijfers-drugsgebruik-in-nederland-in-2022/?vgo_ee=GHN8IKYaWucDAsBHzK4f%2BIpsVVpzmcBI7c0sAXfy0nK99w%3D%3D%3AqDCW%2BlhIAMXLpf6cImugTGNCz3WQ1ezO
  • 63 Yadav MK, Short MD, Aryal R, Gerber C, van den Akker B, Saint CP. Water Res. 2017; 124: 713-727
    Search in Google Scholar
  • 64 Bijlsma L, Emke E, Hernández F, De Voogt P. Chemosphere 2012; 89: 1399-1406
    Search in Google Scholar
  • 65 Khasawneh OF. S, Palaniandy P. Process Saf. Environ. Prot. 2021; 150: 532-556
    Search in Google Scholar
  • 66 Kemacheevakul P, Otani S, Matsuda T, Shimizu Y. Water Sci. Technol. 2012; 66: 2194-2201
    Search in Google Scholar
  • 67 Kasprzyk-Hordern B, Dinsdale RM, Guwy AJ. Water Res. 2009; 43: 363-380
    Search in Google Scholar
  • 68 Kemacheevakul P, Chuangchote S, Otani S, Matsuda T, Shimizu Y. Water Sci. Technol. 2015; 72: 1102-1110
    Search in Google Scholar
  • 69 de Boer MA, Kabbe C, Slootweg JC. Environ. Sci. Technol. 2018; 52: 14564-14565
    Search in Google Scholar
  • 70 Butkovskyi A, Leal LH, Zeeman G, Rijnaarts HH. M. Environ. Res. 2017; 156: 434-442
    Search in Google Scholar
  • 71 Ye ZL, Deng Y, Lou Y, Ye X, Chen S. Front. Environ. Sci. Eng. 2018; 12: 1-7
    Search in Google Scholar
  • 72 European Commission. Regulation (EU) 2019/1009 of the European Parliament and of the Council of 5 June 2019 Laying down Rules on the Making Available on the Market of EU Fertilising Products and Amending Regulations (EC) No 1069/2009 and (EC) No 1107/2009 and Repealing Regula. European Commission; 2019
    Search in Google Scholar
  • 73 Fu Q, Fedrizzi D, Kosfeld V, Schlechtriem C, Ganz V, Derrer S, Rentsch D, Hollender J. Environ. Sci. Technol. 2020; 54: 4400-4408
    Search in Google Scholar