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DOI: 10.1055/a-2573-9069
Efficacy and safety of endoscopic intraperitoneal subserosal dissection for gastric submucosal tumors with extraluminal growth pattern
Authors
Supported by: Biomedical Support Project of Shanghai 21S31904000
Supported by: China Postdoctoral Science Foundation 2023M730664
Clinical Trial:
Registration number (trial ID): ChiCTR2200067022, Trial registry: Chinese Clinical Trial Registry (http://www.chictr.org/), Type of Study: Prospective single center study
Abstract
Background
Endoscopic intraperitoneal subserosal dissection (EISD) has been reported to be a promising modified tunneling technique for gastric submucosal tumors (SMTs) with a predominantly extraluminal growth pattern. We evaluated the safety and efficacy of EISD for gastric extraluminal SMTs.
Methods
We prospectively enrolled consecutive patients who underwent EISD for gastric extraluminal SMTs between October 2018 and March 2024. Clinicopathological characteristics and procedure-related parameters were analyzed.
Results
10 patients with 11 gastric extraluminal SMTs were included. The mean (SD) longest and shortest specimen diameters were 2.1 (0.9) cm (range 0.5–4.0) and 1.8 (0.7) cm (range 0.4–3.0), respectively. All SMTs (100%) were resected en bloc, and 10 (90.9%) were retrieved en bloc. The mean (SD) resection and suture times were 58.9 (31.5) minutes (range 26–125) and 12.4 (10.1) minutes (range 3–25), respectively. Two patients experienced type I mucosal injury at the tumor site, and no major adverse events occurred. The mean postoperative hospital stay was 3.4 (SD 0.8) days (range 3–5). No recurrence or metastasis occurred during a mean follow-up period of 32.1 (SD 18.8) months (range 7–71).
Conclusions
EISD appeared to be a feasible and safe method for removing gastric extraluminal SMTs in selected patients.
Publication History
Received: 09 December 2024
Accepted after revision: 02 April 2025
Accepted Manuscript online:
03 April 2025
Article published online:
15 May 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
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