Endoscopic treatment of Zenker’s diverticulum: how can the size affect the selection of the technique?

Endoscopy 2025; 57(09): 1074
DOI: 10.1055/a-2614-8465

Letter to the editor

Konstantina Dimopoulou

¹Department of Gastroenterology, Red Cross Hospital, Athens, Greece

,

Marianna Spinou

¹Department of Gastroenterology, Red Cross Hospital, Athens, Greece

,

Magdalini Velegraki

²Department of Gastroenterology, Venizeleion General Hospital, Heraklion, Crete, Greece

,

Petros Zormpas

¹Department of Gastroenterology, Red Cross Hospital, Athens, Greece

,

Gregorios A. Paspatis

²Department of Gastroenterology, Venizeleion General Hospital, Heraklion, Crete, Greece

,

¹Department of Gastroenterology, Red Cross Hospital, Athens, Greece

References
1 Almario JA, Mehta A, Shrigiriwar A. et al. Short-term clinical and technical outcomes of a modified Zenker’s peroral endoscopic myotomy with mucosal flap incision. Endoscopy 2025; 57: 348-353
2 Tribonias G, Dimopoulou K, Zormpas P. et al. eP584 Prospective comparison of Z-POEM + Mucosectomy (Z-POEM + M) with flexible endoscopic septotomy (FES) in large (>4cm) zenker’s diverticula. Endoscopy 2025; 57: s489
3 Al Ghamdi SS, Farha J, Moran RA. et al. Zenker’s peroral endoscopic myotomy, or flexible or rigid septotomy for Zenker’s diverticulum: a multicenter retrospective comparison. Endoscopy 2022; 54: 345-351
4 Delgado LM, Meine GC, Santo P. et al. Endoscopic submucosal tunneling techniques versus flexible endoscopic septotomy for Zenker’s diverticulum: a systematic review and meta-analysis. Gastrointest Endosc 2025; 101: 751-761 e730
5 Spadaccini M, Maselli R, Chandrasekar VT. et al. Submucosal tunnelling techniques for Zenker’s diverticulum: a systematic review of early outcomes with pooled analysis. Eur J Gastroenterol Hepatol 2021; 33: e78-e83