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DOI: 10.1055/a-2648-7338
An anatomically designed duodenal stent with physiological drainage: effective endoscopic rescue in persistent perforation
Authors
Gefördert durch: “Pioneer” and “Leading Goose” R&D Program of Zhejiang 2025C02139
Gefördert durch: Program of Taizhou Science and Technology Grant 23ywa33
Gefördert durch: Scientific Research Foundation of Taizhou Enze Medical Center Grant 24EZCG02
Gefördert durch: Major Research Program of Taizhou Enze Medical Center Grant 19EZZDA2
Gefördert durch: Open Project Program of Key Laboratory of Minimally Invasive Techniques and Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province 21SZDSYS01
Gefördert durch: Doctoral Fund of Taizhou Enze Medical Center Grant 2018BSKYQDJJ14
Gefördert durch: Medical Science and Technology Project of Zhejiang Province 2024KY1788, 2022PY101

A 70-year-old woman with a refractory duodenal ulcer developed a 1.5-cm perforation at the duodenal bulb following two failed attempts at endoscopic hemostasis ([Fig. 1]). Placement of an over-the-scope clip for closure was unsuccessful, and resulted in sepsis.


A nitinol duodenal covered stent (22 mm in diameter, 10 cm in length) was deployed endoscopically ([Fig. 2], [Video 1]). This stent integrates three key innovations: (i) a tripartite anchoring system – an umbrella-shaped gastric component for antral apposition, a cylindrical pyloric segment for radial fixation, and a bulbous duodenal anchor for coaptation; (ii) a papilla-aligned fenestration within the membranous mid-section to preserve physiological pancreatobiliary drainage; and (iii) optimized radial force distribution across segmented zones to minimize migration. Follow-up at 15 days confirmed closure of the complete perforation, and the stent was safely retrieved.


Duodenal perforations are challenging owing to anatomical fragility and the enzyme-rich secretions [1] [2]. Conventional stents risk migration and obstructing drainage, thereby exacerbating leaks [3]. An anatomically designed duodenal stent uniquely addresses these limitations: its anchoring system ensures stable positioning without tissue injury, while the fenestration aligns precisely with the papilla, allowing continuous biliary/pancreatic flow into the bowel lumen. This design prevents reflux-related complications and promotes fistula healing by isolating the defect from digestive enzymes. The case underscores the stent’s dual role as a mechanical sealant and physiological conduit, which may be particularly critical in elderly patients with impaired healing.
Endoscopy_UCTN_Code_TTT_1AO_2AZ
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Publikationsverlauf
Artikel online veröffentlicht:
20. August 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
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References
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