ABSTRACT
Despite emerging evidence from randomized controlled trials and meta-analyses questioning
its use, mechanical bowel preparation (MBP) continues to hold an accepted place among
surgeons. MBP has been administered to patients for over a century, and though the
methods and agents used for intestinal cleansing have evolved over time, many surgeons
still embrace MBP as a necessary, essential regimen. The accepted rationale for MBP
includes evacuation of stool to allow visualization of the luminal surfaces as well
as to reduce the fecal flora, which is believed to translate into lower risk of infectious
and anastomotic complications at surgery. The authors describe the history of MBP
as it relates to colorectal surgery and review the agents currently used for mechanical
bowel preparation. Additionally, they summarize the recent trials, meta-analyses,
and other emerging data from the medical literature that suggest MBP offers no benefit
as a preoperative measure and question its place in current surgical practice.
KEYWORDS
Mechanical bowel preparation - colorectal surgery - polyethylene glycol - sodium phosphate
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James E DuncanM.D.
Department of Surgery, National Naval Medical Center (NNMC)
8901 Wisconsin Ave., Bethesda, MD 20889
Email: james.duncan@med.navy.mil