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Semin Plast Surg 2009; 23(2): 141-147
DOI: 10.1055/s-0029-1214166
© Thieme Medical Publishers

Adjunctive Therapies in the Treatment of Osteomyelitis

Robert C. Fang1 , Robert D. Galiano1
  • 1Division of Plastic and Reconstructive Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois
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Publication History

Publication Date:
30 April 2009 (online)

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ABSTRACT

The current management for chronic osteomyelitis centers on adequate antibiotic coverage and surgical debridement of nonviable tissue. The eradication of osteomyelitis, however, often involves a prolonged and frustrating course of management. Nonsurgical adjunctive modalities have not been widely used, mostly due to a lack of perceived efficacy, and have remained in a state of infancy. In this article, we will outline the rationale, current status, and evidence for several potential adjuncts to osteomyelitis management.

KEYWORDS

Osteomyelitis - adjunctive therapy - hyperbaric oxygen therapy - biofilm - growth factor

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Robert D GalianoM.D. 

Assistant Professor of Surgery, Division of Plastic and Reconstructive Surgery, Department of Surgery

Northwestern University Feinberg School of Medicine, Galter Pavilion 19-250, 675 N. St. Clair Street, Chicago, IL 60611

Email: rgaliano@nmh.org