Four-Component Synthesis of
Imidazolinium-Fused Heterocycles from Ugi-Smiles
Couplings

Anaëlle Barthelon; Xavier-Frédéric Legoff; Laurent El Kaim; Laurence Grimaud

doi:10.1055/s-0029-1218550

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Synlett 2010(1): 153-157
DOI: 10.1055/s-0029-1218550

LETTER

Four-Component Synthesis of Imidazolinium-Fused Heterocycles from Ugi-Smiles Couplings

Anaëlle Barthelon^a, Xavier-Frédéric Legoff^b, Laurent El Kaim*^a, Laurence Grimaud*^a
^a Laboratoire Chimie et Procédés, Ecole Nationale Supérieure de Techniques Avancées, 32 Bd Victor, 75739 Paris Cedex 15, France
^b Laboratoire Hétéroéléments et Coordination, Ecole Polytechnique, CNRS, Route de Saclay, 91128 Palaiseau Cedex, France
Fax: +33(1)45528322; e-Mail: laurent.elkaim@ensta.fr; e-Mail: laurence.grimaud@ensta.fr;

Further Information

Publication History

Received 8 October 2009
Publication Date:
14 December 2009 (online)

Abstract
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Abstract

New imidazolinium-fused scaffolds are synthesized via a one-pot, two-step procedure involving a Ugi-Smiles coupling of mercaptotriazine derivatives with an isocyanide, an aldehyde, and a primary amine.

Key words

triazine - mercaptan - Ugi-Smiles - multicomponent reaction - thioamide

References and Notes

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The crystallographic data can be obtained free of charge under the reference CCDC 730687 at the Cambridge Crystallographic Data Centre (www.ccdc.cam.ac.uk/data_request_cif).