Endoscopy 2010; 42(3): 228-231
DOI: 10.1055/s-0029-1243859
Case report/series

© Georg Thieme Verlag KG Stuttgart · New York

Endoscopic ultrasound-guided fine-needle aspiration with or without flow cytometry for the diagnosis of primary pancreatic lymphoma – a case series

M.  Khashab1 , M.  Mokadem1 , J.  DeWitt1 , R.  Emerson2 , S.  Sherman1 , J.  LeBlanc1 , L.  McHenry1 , A.  Al-Rashdan1 , M.  Al-Haddad1
  • 1Department of Medicine, and Clarian/IU Digestive Diseases Center, Indiana University School of Medicine, Indianapolis, Indiana, USA
  • 2Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA
Further Information

Publication History

submitted 2 September 2009

accepted after revision 12 November 2009

Publication Date:
25 January 2010 (online)

The role of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) with flow cytometry for the diagnosis of primary pancreatic lymphoma (PPL) has not been previously described. Our aims were to describe the EUS features of PPL and the role of EUS-FNA with and without flow cytometry in the diagnosis of 16 patients. When EUS-FNA with flow cytometry was compared with EUS-FNA without flow cytometry, the sensitivities for diagnosing non-Hodgkin’s lymphoma were 84.6 % versus 30.8 %, respectively (P = 0.01). EUS-FNA with flow cytometry is a valuable tool to diagnose PPL. Flow cytometry analysis complements traditional assessment by standard cytology.

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M. Al-HaddadMD 

Assistant Professor of Clinical Medicine
Indiana University School of Medicine

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Email: moalhadd@iupui.edu