Endoscopy 2011; 43(6): 545-548
DOI: 10.1055/s-0030-1256196
Case report/series

© Georg Thieme Verlag KG Stuttgart · New York

Endoscopic treatment of gastrointestinal fistulas using an over-the-scope clip (OTSC) device: Case series from a tertiary referral center

R.  Manta1 , M.  Manno1 , H.  Bertani1 , C.  Barbera1 , F.  Pigò1 , V.  Mirante2 , E.  Longinotti2 , G.  Bassotti3 , R.  Conigliaro1
  • 1Gastroenterology and Endoscopy Unit, S. Agostino Estense Civil Hospital, Modena, Italy
  • 2Department of Surgery, S. Agostino Estense Civil Hospital, Modena, Italy
  • 3Gastroenterology and Hepatology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy
Further Information

Publication History

submitted 15 September 2010

accepted after revision 9 December 2010

Publication Date:
15 March 2011 (online)

Gastrointestinal perforations and post-surgical fistulas are dreaded complications that dramatically increase morbidity and mortality. A new endoscopic over-the-scope clip (OTSC) system may be potentially useful for sealing visceral perforations in several clinical settings. We evaluated the advantages and clinical impact of the placement of OTSCs on the management of non-malignant gut leaks in 12 consecutive patients. OTSCs of 9.5 or 10.5 mm were used, according to the diameter of the defect within the wall. The indications for treatment were mainly related to post-surgical fistulas. Healing of the fistula was assessed by endoscopic or radiological means, and failed only once. No OTSC-related complications occurred. Endoscopic closure of perforations and post-surgical fistulas with the OTSC system is a simple and minimally invasive technique. This approach, when feasible, may be less expensive and more advantageous than a surgical approach.


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R. MantaMD 

Gastroenterology and Endoscopy Unit
Nuovo Ospedale Civile Sant’Agostino Estense

Viale Giardini 1355
Baggiovara, Modena, Italy

Fax: +39-059-3961216

Email: r.manta@libero.it