Neonatal Listeriosis: The Importance of Placenta Histological Examination—A Case Report

Abstract

Neonatal listeriosis is not a rare disease, but it is infrequently diagnosed and reported in the literature. Herein we report a case of listeria lethal sepsis, followed by increased cytokines levels in the cord blood, in which diagnosis was made possible by histological examination of the placenta.

Keywords

Neonatal listeriosis - chorioamnionitis - sepsis - Listeria monocytogenes - cytokine

• References

• 1 Bortolussi R. Listeriosis: a primer. CMAJ 2008; 179: 795-797
• 2 Reddy UM, Fry A, Pass R, Ghidini A. Infectious diseases and perinatal outcomes. Emerg Infect Dis; 2004. Available at: http://www.cdc.gov/NCIDOD/EID/vol10no11/04-0623_10.htm . Accessed February 23, 2010
• 3 Almeida GN, Gibbs PA, Hogg TA, Teixeira PC. Listeriosis in Portugal: an existing but under reported infection. BMC Infect Dis 2006; 6: 153-
• 4 Bennett L. Listeria monocytogenes. In: Mandel GL, Bennet JE, Dolin R, eds. Principles and Practice of Infectious Diseases. New York: Churchill Livingstone; 2005: 2478-2483
• 5 Romero R, Espinoza J, Gonçalves LF, Kusanovic JP, Friel LA, Nien JK. Inflammation in preterm and term labour and delivery. Semin Fetal Neonatal Med 2006; 11: 317-326
• 6 Paananen R, Husa AK, Vuolteenaho R, Herva R, Kaukola T, Hallman M. Blood cytokines during the perinatal period in very preterm infants: relationship of inflammatory response and bronchopulmonary dysplasia. J Pediatr 2009; 154: 39-43, e3
• 7 Cossart P, Toledo-Arana A. Listeria monocytogenes, a unique model in infection biology: an overview. Microbes Infect 2008; 10: 1041-1050
• 8 Williams D, Irvin EA, Chmielewski RA, Frank JF, Smith MA. Dose-response of Listeria monocytogenes after oral exposure in pregnant guinea pigs. J Food Prot 2007; 70: 1122-1128
• 9 Huang YT, Chen SU, Wu MZ , et al. Molecular evidence for vertical transmission of listeriosis, Taiwan. J Med Microbiol 2006; 55 (Pt 11) 1601-1603
• 10 Puopolo KM. Bacterial and fungal infections. In: Cloherty JP, Eichenwald EC, Stark AR, eds. Manual of Neonatal Care. Philadelphia: Lippincott Williams & Williams; 2008: 286-2872
• 11 Heras C, García-Patos V, Palacio L , et al. Listeriosis neonatal. Actas Dermosifiliogr 2006; 97: 59-61
• 12 Jackson KA, Iwamoto M, Swerdlow D. Pregnancy-associated listeriosis. Epidemiol Infect 2010; 138: 1503-1509 (Epub ahead of print)
• 13 Srivastava S, Sen MR, Kumar A, Anupurba S. Neonatal listeriosis. Indian J Pediatr 2005; 72: 1059-1060
• 14 Goulet V, Hedberg C, Le Monnier A, de Valk H. Increasing incidence of listeriosis in France and other European countries. Emerg Infect Dis 2008; 14: 734-740
• 15 Hsieh WS, Tsai LY, Jeng SF , et al. Neonatal listeriosis in Taiwan, 1990–2007. Int J Infect Dis 2009; 13: 193-195
• 16 Siegman-Igra Y, Levin R, Weinberger M , et al. Listeria monocytogenes infection in Israel and review of cases worldwide. Emerg Infect Dis 2002; 8: 305-310 Erratum in: Emerg Infec Dis 2002;8:554
• 17 Chen SY, Lu FL, Lee PI , et al. Neonatal listeriosis. J Formos Med Assoc 2007; 106: 161-164
• 18 Hof H. An update on the medical management of listeriosis. Expert Opin Pharmacother 2004; 5: 1727-1735
• 19 Faye-Petersen OM, Heller DS, Joshi VV. Lesions of the placenta as a whole or of the placenta disk. In: Faye-Petersen OM, Heller DS, Joshi VV, eds. Handbook of Placental Pathology. Boca Raton, FL: Taylor and Francis Group; 2006. 96.
• 20 Al-Adnani M, Sebire NJ. The role of perinatal pathological examination in subclinical infection in obstetrics. Best Pract Res Clin Obstet Gynaecol 2007; 21: 505-521
• 21 Driscoll SG, Gorbach A, Feldman D. Congenital listeriosis: diagnosis from placental studies. Oncologia 1962; 20: 216-220