Hebamme 2011; 24(1): 8-15
DOI: 10.1055/s-0031-1275539
Schwangerschaft
Übelkeit
© Hippokrates Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG

Sind Übelkeit und Erbrechen evolutionäre Mechanismen der Anpassung an die Schwangerschaft?

Sebastian Kohl1 , Franz Kainer2 , Wulf Schiefenhövel3
  • 1Innsbruck
  • 2München
  • 3Andechs
Further Information

Publication History

Publication Date:
22 March 2011 (online)

Übelkeit und Erbrechen während der Schwangerschaft sind ein häufiges und bisher uneinheitlich interpretiertes Phänomen. Wir führten dazu eine kulturenvergleichende Untersuchung an 565 Müttern in Südafrika, Guatemala und Deutschland durch. Die Ergebnisse liefern einen neuen Ansatz, der die möglichen evolutionären Vorteile des Phänomens erklärt.

Literatur

  • 1 Gadsby R, Barnie-Adshead A M, Jagger C. A prospective study of nausea and vomiting during pregnancy.  Br J Gen Pract. 1993;  43 245-48
  • 2 Flaxman S M, Sherman P W. Morning sickness: a mechanism for protecting mother and embryo.  Q Rev Biol. 2000;  75 113-48
  • 3 Jarnfelt-Samsioe A, Samsioe G, Velinder G M. Nausea and vomiting in pregnancy – a contribution to its epidemiology.  Gynecol Obstet Invest. 1983;  16 221-29
  • 4 Weigel R M, Weigel M M. Nausea and vomiting of early pregnancy and pregnancy outcome. A meta-analytical review.  Br J Obstet Gynaecol. 1989;  96 1312-18
  • 5 Klebanoff M A, Koslowe P A, Kaslow R, Rhoads G G. Epidemiology of vomiting in early pregnancy.  Obstet Gynecol. 1985;  66 612-16
  • 6 Tierson F D, Olsen C L, Hook E B. Nausea and vomiting of pregnancy and association with pregnancy outcome.  Am J Obstet Gynecol. 1986;  155 1017-22
  • 7 Safari H R, Fassett M J, Souter I C, Alsulyman O M, Goodwin T M. The efficacy of methylprednisolone in the treatment of hyperemesis gravidarum: a randomized, double-blind, controlled study.  Am J Obstet Gynecol. 1998;  179 921-24
  • 8 Broussard C N, Richter J E. Nausea and vomiting of pregnancy.  Gastroenterol Clin North Am. 1998;  27 123-51
  • 9 Tsang I S, Katz V L, Wells S D. Maternal and fetal outcomes in hyperemesis gravidarum.  Int J Gynaecol Obstet. 1996;  55 231-35
  • 10 Profet M. Pregnancy sickness as adaptation: An deterant to maternal ingestion of teratogens. In: Berkow J, Cosmides L, Tooby J, editors. The adapted mind. New York: Oxford University Press; 1992: p. 327-65
  • 11 Williams G C, Nesse R M. The dawn of Darwinian medicine.  Q Rev Biol. 1991;  66 1-22
  • 12 Fessler D M. Reproductive immunosupression and diet. An evolutionary perspective on pregnancy sickness and meat consumption.  Curr Anthropol. 2002;  43 19-61
  • 13 Hook E B. Dietary cravings and aversions during pregnancy.  Am J Clin Nutr. 1978;  31 1355-62
  • 14 Deutsch J A. Pregnancy sickness as an adaptation to concealed ovulation.  Riv Biol. 1994;  87 277-95
  • 15 Koren G, Boskovic R, Hard M, Maltepe C, Navioz Y, Einarson A. Motherisk-PUQE (pregnancy-unique quantification of emesis and nausea) scoring system for nausea and vomiting of pregnancy.  Am J Obstet Gynecol. 2002;  186 S228-S231
  • 16 Bowlby J. Attachment. London: Hogrth Press; 1969
  • 17 Tan P C, Jacob R, Quek K F, Omar S Z. Pregnancy outcome in hyperemesis gravidarum and the effect of laboratory clinical indicators of hyperemesis severity.  J Obstet Gynaecol Res. 2007;  33 457-64
  • 18 Depue R H, Bernstein L, Ross R K, Judd H L, Henderson B E. Hyperemesis gravidarum in relation to estradiol levels, pregnancy outcome, and other maternal factors: a seroepidemiologic study.  Am J Obstet Gynecol. 1987;  156 1137-41
  • 19 Kallen B. Hyperemesis during pregnancy and delivery outcome: a registry study.  Eur J Obstet Gynecol Reprod Biol. 1987;  26 291-302
  • 20 Koren G, Maltepe C, Navioz Y, Wolpin J. Recall bias of the symptoms of nausea and vomiting of pregnancy.  Am J Obstet Gynecol. 2004;  190 485-88
  • 21 Bayley T M, Dye L, Jones S, DeBono M, Hill A J. Food cravings and aversions during pregnancy: relationships with nausea and vomiting.  Appetite. 2002;  38 45-51
  • 22 Wijewardene K, Fonseka P, Goonaratne C. Dietary cravings and aversions during pregnancy.  Indian J Public Health. 1994;  38 95-98
  • 23 Knox B, Kremer J, Pearce J. Food fads during pregnancy: a question of taste?.  Appetite. 1994;  23 288
  • 24 Nordin S, Broman D A, Olofsson J K, Wulff M. A longitudinal descriptive study of self-reported abnormal smell and taste perception in pregnant women.  Chem Senses. 2004;  29 391-402
  • 25 Swallow B L, Lindow S W, Masson E A, Hay D M. Women with nausea and vomiting in pregnancy demonstrate worse health and are adversely affected by odours.  J Obstet Gynaecol. 2005;  25 544-49
  • 26 Deuchar N. Nausea and vomiting in pregnancy: a review of the problem with particular regard to psychological and social aspects.  Br J Obstet Gynaecol. 1995;  102 6-8
  • 27 Uddenberg N, Nilsson A, Almgren P. Nausea in Pregnancy: Psychological and Psychosomatic Aspects.  Journal of Psychosomatic Research. 1971;  15 269-76
  • 28 Leeners B, Sauer I, Rath W. Nausea and vomiting in early pregnancy/hyperemesis gravidarum. Current status of psychosomatic factors.  Z Geburtshilfe Neonatol. 2000;  204 128-34
  • 29 O’Brien B, Naber S. Nausea and vomiting during pregnancy: effects on the quality of women‘s lives.  Birth. 1992;  19 138-43
  • 30 Katon W J, Ries R K, Bokan J A, Kleinman A. Hyperemesis gravidarum: a biopsychosocial perspective.  Int J Psychiatry Med. 1980;  10 151-62
  • 31 Fait V, Sela S, Ophir E, Khoury S, Nissimov J, Tkach M. et al . Hyperemesis gravidarum is associated with oxidative stress.  Am J Perinatol. 2002;  19 93-98
  • 32 Askew E W. Work at high altitude and oxidative stress: antioxidant nutrients.  Toxicology. 2002;  180 107-19
  • 33 Pepper G V, Craig R S. Rates of nausea and vomiting in pregnancy and dietary characteristics across populations.  Proc Biol Sci. 2006;  273 2675-79
  • 34 de Silva N. Family medicine in the undergraduate curriculum.  Ceylon Med J. 1995;  40 148-50
  • 35 Bloom T, Curry M A, Durham L. Abuse and psychosocial stress as factors in high utilization of medical services during pregnancy.  Issues Ment Health Nurs. 2007;  28 849-66
  • 36 Weigel M M, Caiza M E, Lascano Y, Barreno G, Mosquera L. Early pregnancy nausea and vomiting in a high-altitude Andean population.  Int J Gynaecol Obstet. 2000;  69 9-21
  • 37 Chou F H, Avant K C, Kuo S H, Fetzer S J. Relationships between nausea and vomiting, perceived stress, social support, pregnancy planning, and psychosocial adaptation in a sample of mothers: a questionnaire survey.  Int J Nurs Stud. 2008;  45 1185-91
  • 38 Markl G E, Strunz-Lehner C, Egen-Lappe V, Lack N, Hasford J. The association of psychosocial factors with nausea and vomiting during pregnancy.  J Psychosom Obstet Gynaecol. 2008;  29 17-22
  • 39 David M, Borde T, Kenenich H. Is Hyperemisis gravidarum a Disease of Immigrants?.  Geburtsh Frauenheilk. 2002;  62 327-32
  • 40 Schiefenhövel W, Schiefenhövel-Barthel S. Das menschliche Leben zwischen Werden und Vergehen. Leipzig u. Mannheim: Brockhaus-Redaktion (Hrsg.); 1999: p. 32-91
  • 41 Fairweather D V. Nausea and vomiting in pregnancy.  Am J Obstet Gynecol. 1968;  102 135-75
  • 42 Gluckman P, Hanson M. The Fetal Matrix: Evolution, Development and Disease. Cambridge, United Kingdom; 2005
  • 43 Furneaux E C, Langley-Evans A J, Langley-Evans S C. Nausea and vomiting of pregnancy: endocrine basis and contribution to pregnancy outcome.  Obstet Gynecol Surv. 2001;  56 775-82

Anschrift des Autors:

Dr. med. Sebastian Kohl

Innere Medizin III

Universitätsklinik Innsbruck

Anichstraße 35

A-6020 Innsbruck

Email: kohl_sebastian@hotmail.com