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AJP Rep 2011; 01(02): 095-098
DOI: 10.1055/s-0031-1285982
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Acute Fetal Anemia Diagnosed by Middle Cerebral Artery Doppler Velocimetry in Stage V Twin–Twin Transfusion Syndrome

Jennifer Salcedo
1   Department of Obstetrics and Gynecology, Irvine, Orange, California
,
Esther Friedrich
2   Division of Maternal-Fetal Medicine, University of California, Irvine, Orange, California
,
Deborah A. Wing
2   Division of Maternal-Fetal Medicine, University of California, Irvine, Orange, California
,
Manuel Porto
2   Division of Maternal-Fetal Medicine, University of California, Irvine, Orange, California
› Author Affiliations
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Publication History

Publication Date:
03 August 2011 (online)

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Abstract

In stage V twin–twin transfusion syndrome (TTTS), up to 50% of surviving twins die or experience permanent disabilities, likely due to acute intertwin hemorrhage resulting in sudden severe anemia of the survivor. Although fetal middle cerebral artery (MCA) Doppler studies demonstrate strong correlation with fetal hemoglobin values, acute hemorrhagic events are more difficult to diagnose, and optimal timing of delivery of the survivor poses an obstetric dilemma. We report a case of newly diagnosed stage V TTTS at 28 weeks gestation, complicated by acute severe anemia diagnosed by significantly abnormal fetal MCA Doppler studies. The anemic twin was urgently delivered and is doing well without significant sequelae.

Keywords

Fetal anemia - fetal demise - Doppler velocimetry - twin–twin transfusion syndrome
 

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