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AJP Rep 2013; 03(01): 005-008
DOI: 10.1055/s-0032-1329125
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Glucose-6-Phosphate Dehydrogenase Deficiency and Adrenal Hemorrhage in a Filipino Neonate with Hyperbilirubinemia

Akira Ohishi
1   Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu, Japan
,
Daizo Ueno
1   Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu, Japan
,
Tsutomu Ogata
1   Department of Pediatrics, Hamamatsu University School of Medicine, Hamamatsu, Japan
› Author Affiliations
Further Information

Publication History

03 December 2011

20 June 2012

Publication Date:
16 November 2012 (online)

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Abstract

We report on a Filipino neonate with early onset and prolonged hyperbilirubinemia who was delivered by a vacuum extraction due to a prolonged labor. Subsequent studies revealed adrenal hemorrhage and glucose-6-phosphate dehydrogenase (G6PD) deficiency. It is likely that asphyxia and resultant hypoxia underlie the occurrence of adrenal hemorrhage and the clinical manifestation of G6PD deficiency and that the presence of the two events explains the early onset and prolonged hyperbilirubinemia of this neonate. Our results represent the importance of examining possible underlying factors for the development of severe, early onset, or prolonged hyperbilirubinemia.

Keywords

adrenal hemorrhage - glucose-6-phosphate dehydrogenase deficiency - hyperbilirubinemia - neonate.
 

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