Nickel(0)-Promoted Carboxylation of Allenamides with Carbon Dioxide via a Nickelalactone Intermediate

Abstract

Nickel(0)-promoted carboxylation of N-allenylamides (allenamides) with carbon dioxide proceeded via a nickelalactone intermediate to give β-amino acid derivatives. It was also found that the regioselectivity at the oxidative addition stage was strongly affected by the substituents on the allene part.

Key words

nickel - allenamide - carbon dioxide - fixation - β-amino acid

• References and Notes


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