Endoscopy 2014; 46(12): 1116-1118
DOI: 10.1055/s-0034-1377630
Case series
© Georg Thieme Verlag KG Stuttgart · New York

Esophageal capsule endoscopy is a useful tool in patients with hemophilia

Anastasios Koulaouzidis
1   Centre for Liver and Digestive Disorders, Royal Infirmary of Edinburgh, Scotland, United Kingdom
Yun Lin Ang
2   Medical School, University of Edinburgh, Edinburgh, Scotland, United Kingdom
Sarah Douglas
1   Centre for Liver and Digestive Disorders, Royal Infirmary of Edinburgh, Scotland, United Kingdom
John N. Plevris
1   Centre for Liver and Digestive Disorders, Royal Infirmary of Edinburgh, Scotland, United Kingdom
3   Department of Haematology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom
› Author Affiliations
Further Information

Publication History

Publication Date:
10 September 2014 (online)

Esophageal capsule endoscopy (ECE) is considered to be an alternative to conventional esophagogastroduodenoscopy (EGD); however, its indications continue to expand. This report presents results from the use of ECE in patients with hemophilia at a tertiary referral academic center over a 7-year period. A total of 16 patients with hemophilia, who were all at risk of new-variant Creutzfeldt-Jakob disease due to previous treatment with UK plasma-derived pooled blood products, underwent a total of 28 ECE examinations. Main outcomes were the diagnostic yield of ECE, requirement for subsequent conventional EGD, and any variceal bleeding episodes during the follow-up period. The overall diagnostic yield was 67.8 % (19 /28 ECEs). Only one patient underwent conventional EGD, for esophageal biopsies. There were no variceal hemorrhage events in any of the patients on variceal screening follow-up. ECE is a useful and acceptable alternative to conventional endoscopy in selected patient groups (i. e. patients with hemophilia). In this group, ECE can eliminate the need for prior administration of clotting factors.

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