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Synlett 2015; 26(04): 461-466
DOI: 10.1055/s-0034-1378938
DOI: 10.1055/s-0034-1378938
letter
Click To Bind: Microwave-Assisted Solid-Phase Synthesis of Peptoids Incorporating Pyridine–Triazole Ligands and Their Copper(II) Complexes
Further Information
Publication History
Received: 08 September 2014
Accepted after revision: 20 October 2014
Publication Date:
21 November 2014 (online)
Abstract
We describe a fast and efficient incorporation of the ligands 2-(1H-1,2,3-triazol-4-yl)pyridine and 2-(1H-1,2,3-triazol-1-ylmethyl)-pyridine into N-substituted glycine peptoid oligomers by the azide–alkyne cycloaddition (click) reaction on a solid support under microwave irradiation. Peptoids bearing these ligands formed stable complexes with copper(II).
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1378938.
- Supporting Information
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