Dedicated to ‘uncle Peter’, in deep admiration for his marvelius contributions to
chemical synthesis, including Synlett.
A thermally promoted synthesis of 3,5-diketo esters via a Mukaiyama–Claisen reaction
of 4H-1,3-dioxin-4-one derivatives with silyl enolates has been developed. The desired
oligocarbonyl compounds were obtained with moderate to good yields.
Key words
3,5-diketo esters - Mukaiyama–Claisen reaction - thermal reaction - silylated nucleophiles