Endoscopy 2015; 47(05): 449-452
DOI: 10.1055/s-0034-1390766
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

Endoscopic sleeve gastroplasty for the treatment of obesity

Gontrand Lopez-Nava
1  Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain
,
Manoel P. Galvão
2  Gastro Obeso Center, Gastrointestinal Surgery, São Paulo, São Paulo, Brazil
,
Immacula da Bautista-Castaño
1  Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain
,
Amaya Jimenez
1  Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain
,
Teresa De Grado
1  Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain
,
Juan Pedro Fernandez-Corbelle
1  Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, Madrid, Spain
› Author Affiliations
Further Information

Publication History

submitted 12 April 2014

accepted after revision 15 September 2014

Publication Date:
07 November 2014 (eFirst)

Background and study aims: Emerging endoscopic techniques are minimally invasive and can mimic the anatomic alterations achieved by surgical sleeve gastrectomy. The objective of this study was to evaluate endoscopic sleeve gastroplasty.

Patients and methods: This was a prospective, single-center study of 20 patients who underwent flexible endoscopic suturing for endoluminal gastric volume reduction. A multidisciplinary team provided postprocedure care. Patient status and weight were recorded at baseline, and at 1, 3, and 6 months after the procedure.

Results: There were no adverse events and all patients were discharged in less than 24 hours. Baseline mean body mass index was 38.5 kg/m2, and mean age was 45.8 years. Initial body weight (108.5 ± 14.9 kg) was significantly reduced. Following the procedure, the mean body weight reduction was 8.2 ± 2.5 kg at 1 month (% of initial weight loss 7.6 %; P < 0.05), 13.6 ± 4.8 kg at 3 months (12.4 % weight loss; P < 0.05), and 19.3 ± 8.9 kg at 6 months (17.8 % weight loss; P < 0.05).

Conclusion: Endoscopic sleeve gastroplasty can be effective for the treatment of patients with obesity.