Endoscopy 2015; 47(02): 164-166
DOI: 10.1055/s-0034-1390773
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

Initial experience with endoscopic sleeve gastroplasty: technical success and reproducibility in the bariatric population

Reem Z. Sharaiha
Division of Gastroenterology & Hepatology, Department of Medicine, Weill Cornell Medical College, New York, USA
,
Prashant Kedia
Division of Gastroenterology & Hepatology, Department of Medicine, Weill Cornell Medical College, New York, USA
,
Nikhil Kumta
Division of Gastroenterology & Hepatology, Department of Medicine, Weill Cornell Medical College, New York, USA
,
Ersilia M. DeFilippis
Division of Gastroenterology & Hepatology, Department of Medicine, Weill Cornell Medical College, New York, USA
,
Monica Gaidhane
Division of Gastroenterology & Hepatology, Department of Medicine, Weill Cornell Medical College, New York, USA
,
Alpana Shukla
Division of Gastroenterology & Hepatology, Department of Medicine, Weill Cornell Medical College, New York, USA
,
Louis J. Aronne
Division of Gastroenterology & Hepatology, Department of Medicine, Weill Cornell Medical College, New York, USA
,
Michel Kahaleh
Division of Gastroenterology & Hepatology, Department of Medicine, Weill Cornell Medical College, New York, USA
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Publikationsverlauf

submitted 13. Juli 2014

accepted after revision 02. September 2014

Publikationsdatum:
07. November 2014 (online)

Background and aims: Novel endoscopic techniques have been developed as effective treatments for obesity. Recently, reduction of gastric volume via endoscopic placement of full-thickness sutures, termed endoscopic sleeve gastroplasty (ESG), has been described. Our aim was to evaluate the safety, technical feasibility, and clinical outcomes for ESG.

Patient and methods: Between August 2013 and May 2014, ESG was performed on 10 patients using an endoscopic suturing device. Their weight loss, waist circumference, and clinical outcomes were assessed.

Results: Mean patient age was 43.7 years and mean body mass index (BMI) was 45.2 kg/m2. There were no significant adverse events noted. After 1 month, 3 months, and 6 months, excess weight loss of 18 %, 26 %, and 30 %, and mean weight loss of 11.5 kg, 19.4 kg, and 33.0 kg, respectively, were observed. The differences observed in mean BMI and waist circumference were 4.9 kg/m2 (P = 0.0004) and 21.7 cm (P = 0.003), respectively.

Conclusions: ESG is effective in achieving weight loss with minimal adverse events. This approach may provide a cost-effective outpatient procedure to add to the steadily growing armamentarium available for treatment of this significant epidemic.