Synlett 2016; 27(06): 951-955
DOI: 10.1055/s-0035-1561291
letter
© Georg Thieme Verlag Stuttgart · New York

Copper-Catalyzed Amidation of Arylboronic Acids with Nitriles

He Huang
a  College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, P. R. of China   Email: xiangsk@hotmail.com   Email: wanbiqin1964@126.com
,
Zhong-Tao Jiang
a  College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, P. R. of China   Email: xiangsk@hotmail.com   Email: wanbiqin1964@126.com
,
Yang Wu
a  College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, P. R. of China   Email: xiangsk@hotmail.com   Email: wanbiqin1964@126.com
,
Cheng-Yan Gan
a  College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, P. R. of China   Email: xiangsk@hotmail.com   Email: wanbiqin1964@126.com
,
Jin-Mei Li
a  College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, P. R. of China   Email: xiangsk@hotmail.com   Email: wanbiqin1964@126.com
,
Shi-Kai Xiang*
a  College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, P. R. of China   Email: xiangsk@hotmail.com   Email: wanbiqin1964@126.com
,
Chun Feng
a  College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, P. R. of China   Email: xiangsk@hotmail.com   Email: wanbiqin1964@126.com
,
Bi-Qin Wang*
a  College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, 610068, P. R. of China   Email: xiangsk@hotmail.com   Email: wanbiqin1964@126.com
,
Wei-Te Yang
b  Department of Public Health, Chengdu Medical College, Chengdu, 610500, P. R. of China
› Author Affiliations
Further Information

Publication History

Received: 03 October 2015

Accepted after revision: 22 November 2015

Publication Date:
11 December 2015 (online)


Abstract

A copper-catalyzed amidation of arylboronic acids with nitriles has been developed. This reaction provides an efficient and complementary methodology for the synthesis of various N-arylamides with a broad substrate scope.

Supporting Information

 
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