Journal of Pediatric Biochemistry 2014; 04(02): 077-080
DOI: 10.1055/s-0036-1586464
Review Article
Georg Thieme Verlag KG Stuttgart – New York

Epidemiology of pediatric urolithiasis

Kemal Sarıca
a   Department of Urology, Dr. Lütfi Kırdar Kartal Research and Training Hospital, İstanbul, Turkey
,
Cihangir Çetinel
a   Department of Urology, Dr. Lütfi Kırdar Kartal Research and Training Hospital, İstanbul, Turkey
› Author Affiliations

Subject Editor:
Further Information

Publication History

17 April 2014

17 April 2014

Publication Date:
03 August 2016 (online)

Abstract

Pediatric urolithiasis is an endemic disease in certain parts of the world, namely Turkey and the Far East. As a recurrent pathology which may reveal functional as well and morphologic changes in the urinary tract, environmental factors together with urogenital abnormalities should be evaluated thoroughly in each patient. The aims of management should be complete clearance of stones, treatment of urinary tract infections, and preservation of renal function and prevention of stone recurrence. In addition to certain minimally invasive stone removal procedures, treatment of pediatric urolithiasis requires a detailed metabolic evaluation in all patients on an individual basis. Obstructive pathologies have to be corrected immediately and children with a positive family history should be followed carefully with respect to a high likelihood of stone re-growth and recurrence. Although specific management of each metabolic abnormality seems to be the key factor in the medical management of stone disease, as general advice each child should be forced to adequate fluid intake which will reveal the urine volume increase in accordance with the body mass index. Moreover, medical therapeutic agents that increase urine citrate levels should be encouraged.